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The map label for this gene is sctV

Identifier: 15834984

GI number: 15834984

Start: 424400

End: 426526

Strand: Reverse

Name: sctV

Synonym: TC0365

Alternate gene names: 15834984

Gene position: 426526-424400 (Counterclockwise)

Preceding gene: 15834985

Following gene: 15834983

Centisome position: 39.75

GC content: 41.42

Gene sequence:

>2127_bases
ATGAACAAGCTACTCAATTTTGTCAGTAGAACATTCGGGGGAGACGCGGCCCTGAACATGATAAACAAGTCCAGCGACCT
CATCCTTGCTATGTGGATGTTGGGCGTGGTCTTGATGATCATTATGCCATTGCCTCCAGTTATGGTGGATTTCATGATCA
CCATCAACTTGGCAATCTCCGTATTCCTGCTGATGGTTGCCTTATATATTCCTAGCGCATTGCAACTCTCGGTTTTCCCT
TCCCTACTCCTAATCACCACAATGTTCCGATTAGGAATTAACATCTCTTCTTCCAGACAAATTCTCCTTCATGCTTATGC
AGGGAACGTGATTCAGGCCTTCGGGGACTTCGTCGTTGGAGGAAACTATGTCGTTGGATTTATTATCTTCCTAATCATCA
CCATCATACAGTTTATTGTGGTTACTAAAGGTGCGGAAAGGGTCGCTGAGGTTGCTGCTCGATTCCGATTAGATGCGATG
CCTGGTAAACAGATGGCTATTGATGCTGACCTTCGTGCGGGGATGATTGATGCCACACAAGCTCGCGATAAACGAGCTCA
AATTCAGAAGGAAAGTGAACTTTACGGAGCCATGGACGGAGCCATGAAGTTCATCAAAGGAGACGTTATTGCCGGTATCG
TCATCTCCTTGATTAACATCGTCGGAGGGTTAGTCATTGGTGTCACAATGAAAGGCATGACAATGGCTCAAGCTGCTCAC
ATTTACACCCTCATTACTATTGGGGATGGATTAGTTTCCCAAATTCCCTCCCTATTGATCTCTTTAACCGCTGGTATCGT
AACTACTCGAGTATCTAGTGATAAAGATACAAACCTCGGGAAAGAAATTTCTAGCCAGTTGGTTAAAGAACCTAGAGCCT
TACTCCTCTCTGCGGTAGCTACCTTAGGAATCGGTTTTTTTAAAGGATTCCCTTTATGGTCATTTGCCCTAATGGCTGTT
GTTTTTGCAGTATTAGGTATTTTGTTAATCACCAAGAAAAATTCTCCTGGCAAAAAGGGAAGTTCCAGTTCTTCTACTAC
CGTAGGTGCTGCTGACGGAGCATCGGCCTCAGGAGAAAACTCCGATGATTATGCGCTTACTCTTCCTGTAATTCTCGAAC
TTGGTAAAGATCTTTCCAAACTTATTCAGCAAAGAACAAAATCAGGGCAAAGCTTTGTGGATGATATGATTCCTAAAATG
CGCCAAGCTCTTTATCAAGATATTGGAATTCGCTATCCAGGAATCCACGTACGAACAGATTCCCCTTCTTTAGAAGGGAA
TGATTATATGATTCTTCTTAACGAAGTCCCCTATGTTCGAGGGAAAATTCCTCCTAACCACGTTTTAACAAACGAAGTGG
AAGAAAACCTTTCTCGTTATAATCTACCTTTTATCACTTACAAAAATGCTGCAGGTTTGCCTTCAACTTGGGTCAGCACC
GATGCTCTTACTATTTTAGAAAAAGCAGCTATTAAGTACTGGTCTCCTTTGGAAGTGATTATTCTTCATCTTTCTTACTT
CTTCCATAGAAACTCTCAAGAGTTTCTAGGAATTCAGGAAGTTCGTTCTATGATTGAATTTATGGAACGATCTTTCCCTG
ATCTTGTTAAAGAAGTTACACGCCTTATTCCTCTGCAGAAGCTTACAGAAATTTTCAAGCGTTTAGTTCAGGAGCAAATT
TCCATCAAAGATTTGCGAACCATTTTAGAATCTTTAAGCGAATGGGCCCAAACTGAGAAAGATACTGTATTACTGACAGA
GTATGTACGTTCTTCCTTGAAACTTTATATCAGCTTCAAATTTTCTCAAGGGCAATCAGCAATTTCAGTCTACCTGTTAG
ATCCTGAAATTGAAGAGATGATTCGTGGCGCTATTAAACAAACTTCTGCGGGCTCTTATTTGGCCTTAGATCCAGATTCC
GTAAACCTCATTTTAAAATCCATGCGAATGACTATTACCCCAACACCTCCTGGAGGCCAACCCCCAGTACTGTTGACAGC
AATTGACGTCAGACGCTATGTACGAAAATTAATAGAGACAGAATTTCCTGATATTGCTGTGATTTCTTATCAAGAGGTCT
TACCTGAAATTAGAATCCAGCCTTTAGGAAGAATTCAAATTTTCTAA

Upstream 100 bases:

>100_bases
AGACCACATATGAAGCGGTTGGGGAAATCCTTCTTTACATTACTTCTCTTAATGCGCAAAACATTGAGAATAAAAACATT
AACCAATTCGATAATCTGTA

Downstream 100 bases:

>100_bases
CCGTGAGGTAAGAAGAGATGACTGCATCCGGAGGAGCTGGAGGGTTAGGCGGAACCCAAACAGTAAACGTAGCACAAGCG
CAAGCTGCAGCAGCTACTCA

Product: type III secretion inner membrane protein SctV

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 708; Mature: 708

Protein sequence:

>708_residues
MNKLLNFVSRTFGGDAALNMINKSSDLILAMWMLGVVLMIIMPLPPVMVDFMITINLAISVFLLMVALYIPSALQLSVFP
SLLLITTMFRLGINISSSRQILLHAYAGNVIQAFGDFVVGGNYVVGFIIFLIITIIQFIVVTKGAERVAEVAARFRLDAM
PGKQMAIDADLRAGMIDATQARDKRAQIQKESELYGAMDGAMKFIKGDVIAGIVISLINIVGGLVIGVTMKGMTMAQAAH
IYTLITIGDGLVSQIPSLLISLTAGIVTTRVSSDKDTNLGKEISSQLVKEPRALLLSAVATLGIGFFKGFPLWSFALMAV
VFAVLGILLITKKNSPGKKGSSSSSTTVGAADGASASGENSDDYALTLPVILELGKDLSKLIQQRTKSGQSFVDDMIPKM
RQALYQDIGIRYPGIHVRTDSPSLEGNDYMILLNEVPYVRGKIPPNHVLTNEVEENLSRYNLPFITYKNAAGLPSTWVST
DALTILEKAAIKYWSPLEVIILHLSYFFHRNSQEFLGIQEVRSMIEFMERSFPDLVKEVTRLIPLQKLTEIFKRLVQEQI
SIKDLRTILESLSEWAQTEKDTVLLTEYVRSSLKLYISFKFSQGQSAISVYLLDPEIEEMIRGAIKQTSAGSYLALDPDS
VNLILKSMRMTITPTPPGGQPPVLLTAIDVRRYVRKLIETEFPDIAVISYQEVLPEIRIQPLGRIQIF

Sequences:

>Translated_708_residues
MNKLLNFVSRTFGGDAALNMINKSSDLILAMWMLGVVLMIIMPLPPVMVDFMITINLAISVFLLMVALYIPSALQLSVFP
SLLLITTMFRLGINISSSRQILLHAYAGNVIQAFGDFVVGGNYVVGFIIFLIITIIQFIVVTKGAERVAEVAARFRLDAM
PGKQMAIDADLRAGMIDATQARDKRAQIQKESELYGAMDGAMKFIKGDVIAGIVISLINIVGGLVIGVTMKGMTMAQAAH
IYTLITIGDGLVSQIPSLLISLTAGIVTTRVSSDKDTNLGKEISSQLVKEPRALLLSAVATLGIGFFKGFPLWSFALMAV
VFAVLGILLITKKNSPGKKGSSSSSTTVGAADGASASGENSDDYALTLPVILELGKDLSKLIQQRTKSGQSFVDDMIPKM
RQALYQDIGIRYPGIHVRTDSPSLEGNDYMILLNEVPYVRGKIPPNHVLTNEVEENLSRYNLPFITYKNAAGLPSTWVST
DALTILEKAAIKYWSPLEVIILHLSYFFHRNSQEFLGIQEVRSMIEFMERSFPDLVKEVTRLIPLQKLTEIFKRLVQEQI
SIKDLRTILESLSEWAQTEKDTVLLTEYVRSSLKLYISFKFSQGQSAISVYLLDPEIEEMIRGAIKQTSAGSYLALDPDS
VNLILKSMRMTITPTPPGGQPPVLLTAIDVRRYVRKLIETEFPDIAVISYQEVLPEIRIQPLGRIQIF
>Mature_708_residues
MNKLLNFVSRTFGGDAALNMINKSSDLILAMWMLGVVLMIIMPLPPVMVDFMITINLAISVFLLMVALYIPSALQLSVFP
SLLLITTMFRLGINISSSRQILLHAYAGNVIQAFGDFVVGGNYVVGFIIFLIITIIQFIVVTKGAERVAEVAARFRLDAM
PGKQMAIDADLRAGMIDATQARDKRAQIQKESELYGAMDGAMKFIKGDVIAGIVISLINIVGGLVIGVTMKGMTMAQAAH
IYTLITIGDGLVSQIPSLLISLTAGIVTTRVSSDKDTNLGKEISSQLVKEPRALLLSAVATLGIGFFKGFPLWSFALMAV
VFAVLGILLITKKNSPGKKGSSSSSTTVGAADGASASGENSDDYALTLPVILELGKDLSKLIQQRTKSGQSFVDDMIPKM
RQALYQDIGIRYPGIHVRTDSPSLEGNDYMILLNEVPYVRGKIPPNHVLTNEVEENLSRYNLPFITYKNAAGLPSTWVST
DALTILEKAAIKYWSPLEVIILHLSYFFHRNSQEFLGIQEVRSMIEFMERSFPDLVKEVTRLIPLQKLTEIFKRLVQEQI
SIKDLRTILESLSEWAQTEKDTVLLTEYVRSSLKLYISFKFSQGQSAISVYLLDPEIEEMIRGAIKQTSAGSYLALDPDS
VNLILKSMRMTITPTPPGGQPPVLLTAIDVRRYVRKLIETEFPDIAVISYQEVLPEIRIQPLGRIQIF

Specific function: Could be involved in the secretion of the yop virulence proteins [H]

COG id: COG4789

COG function: function code U; Type III secretory pathway, component EscV

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family [H]

Homologues:

Organism=Escherichia coli, GI1788187, Length=666, Percent_Identity=35.1351351351351, Blast_Score=368, Evalue=1e-103,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001712
- InterPro:   IPR006302 [H]

Pfam domain/function: PF00771 FHIPEP [H]

EC number: NA

Molecular weight: Translated: 78058; Mature: 78058

Theoretical pI: Translated: 8.48; Mature: 8.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKLLNFVSRTFGGDAALNMINKSSDLILAMWMLGVVLMIIMPLPPVMVDFMITINLAIS
CCHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
VFLLMVALYIPSALQLSVFPSLLLITTMFRLGINISSSRQILLHAYAGNVIQAFGDFVVG
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHCC
GNYVVGFIIFLIITIIQFIVVTKGAERVAEVAARFRLDAMPGKQMAIDADLRAGMIDATQ
CHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCEEEECHHHCCCCCHHH
ARDKRAQIQKESELYGAMDGAMKFIKGDVIAGIVISLINIVGGLVIGVTMKGMTMAQAAH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
IYTLITIGDGLVSQIPSLLISLTAGIVTTRVSSDKDTNLGKEISSQLVKEPRALLLSAVA
HEEEEEECCHHHHHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
TLGIGFFKGFPLWSFALMAVVFAVLGILLITKKNSPGKKGSSSSSTTVGAADGASASGEN
HHHHHHHCCCHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCEECCCCCCCCCCCC
SDDYALTLPVILELGKDLSKLIQQRTKSGQSFVDDMIPKMRQALYQDIGIRYPGIHVRTD
CCCEEEHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEECC
SPSLEGNDYMILLNEVPYVRGKIPPNHVLTNEVEENLSRYNLPFITYKNAAGLPSTWVST
CCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHH
DALTILEKAAIKYWSPLEVIILHLSYFFHRNSQEFLGIQEVRSMIEFMERSFPDLVKEVT
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHCCHHHHHHHHHHHHHCCHHHHHHHH
RLIPLQKLTEIFKRLVQEQISIKDLRTILESLSEWAQTEKDTVLLTEYVRSSLKLYISFK
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCEEEEEEEE
FSQGQSAISVYLLDPEIEEMIRGAIKQTSAGSYLALDPDSVNLILKSMRMTITPTPPGGQ
ECCCCCEEEEEEECHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHCEEECCCCCCCC
PPVLLTAIDVRRYVRKLIETEFPDIAVISYQEVLPEIRIQPLGRIQIF
CCEEEEHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHCCCCCCCEEEC
>Mature Secondary Structure
MNKLLNFVSRTFGGDAALNMINKSSDLILAMWMLGVVLMIIMPLPPVMVDFMITINLAIS
CCHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
VFLLMVALYIPSALQLSVFPSLLLITTMFRLGINISSSRQILLHAYAGNVIQAFGDFVVG
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHCC
GNYVVGFIIFLIITIIQFIVVTKGAERVAEVAARFRLDAMPGKQMAIDADLRAGMIDATQ
CHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCEEEECHHHCCCCCHHH
ARDKRAQIQKESELYGAMDGAMKFIKGDVIAGIVISLINIVGGLVIGVTMKGMTMAQAAH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
IYTLITIGDGLVSQIPSLLISLTAGIVTTRVSSDKDTNLGKEISSQLVKEPRALLLSAVA
HEEEEEECCHHHHHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
TLGIGFFKGFPLWSFALMAVVFAVLGILLITKKNSPGKKGSSSSSTTVGAADGASASGEN
HHHHHHHCCCHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCEECCCCCCCCCCCC
SDDYALTLPVILELGKDLSKLIQQRTKSGQSFVDDMIPKMRQALYQDIGIRYPGIHVRTD
CCCEEEHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEECC
SPSLEGNDYMILLNEVPYVRGKIPPNHVLTNEVEENLSRYNLPFITYKNAAGLPSTWVST
CCCCCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHH
DALTILEKAAIKYWSPLEVIILHLSYFFHRNSQEFLGIQEVRSMIEFMERSFPDLVKEVT
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHCCHHHHHHHHHHHHHCCHHHHHHHH
RLIPLQKLTEIFKRLVQEQISIKDLRTILESLSEWAQTEKDTVLLTEYVRSSLKLYISFK
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCEEEEEEEE
FSQGQSAISVYLLDPEIEEMIRGAIKQTSAGSYLALDPDSVNLILKSMRMTITPTPPGGQ
ECCCCCEEEEEEECHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHCEEECCCCCCCC
PPVLLTAIDVRRYVRKLIETEFPDIAVISYQEVLPEIRIQPLGRIQIF
CCEEEEHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHCCCCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11402007 [H]