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The map label for this gene is tlc-1

Identifier: 15834955

GI number: 15834955

Start: 397808

End: 399397

Strand: Reverse

Name: tlc-1

Synonym: TC0335

Alternate gene names: 15834955

Gene position: 399397-397808 (Counterclockwise)

Preceding gene: 15834956

Following gene: 15834954

Centisome position: 37.22

GC content: 42.96

Gene sequence:

>1590_bases
ATGACTCAAACCGCGGAAAAACCTTTTGGAAAATTGCGCTCTTTCCTTTGGCCGATACACATGCATGAGCTAAAGAAAGT
TCTGCCAATGTTCCTAATGTTCTTCTGTATTTCATTCAATTACACGATTTTGAGAGATACAAAAGACACTCTTATCGTCA
CAGCACCAGGCTCTGGAGCAGAAGCCATTCCCTTTATTAAGTTGTGGCTGGTTGTTCCTTCTGCTGTTGTGTTCATGCTT
ATCTACGCAAAGTTAAGCAATATTTTGAGCAAACAGGCTCTTTTCTATGCAGTGCTCTCTCCATTCGTTGTGTTTTTTGC
ACTGTTCCCTTTGGTGATTTACCCATATCGTCATATACTTCACCCAACAGACTTCGCTGATACACTACAGGCCATTCTCC
CTTCTGGGTTCTTAGGCTTCATTGCGATGCTACGCAACTGGACTTTTGCAGCGTTTTATGTTCTTTCCGAACTTTGGGGA
AGTGTAATGCTTTCGCTAATGTTCTGGGGATTTGCAAATGAAATCACTAAAATTAGCGAAGCTAAACGTTTCTACGCTCT
TTTCGGAGTTGGAGCTAACGTAGCTCTCTTAATTTCCGGTCCAGCTATTGTTTGGTCTTCTAAATTACGCGCAAGCTTAG
GTGAAGGCGTAGACCCATGGGGAGTTACTCTTTACTTCTTAATGGCTATGTTCCTGTGTTCTTGTGCCATTATCGCTGCC
TGCTACTGGTGGATGAATCGTTACGTTCTTACTGATCCTAGATTCTATAACCCAGCAGAGCTAAAAGCTAAAAAATCTAA
ACCTAAGATGAGCATGGGCGAGAGCTTCTCTTATCTGTTAAGATCCCCTTACATGCTTCTTCTAGCCTTGCTAGTTATTT
GCTACGGAGTTTGCATCAACCTTGTTGAAGTAACTTGGAAGAGCCAGCTCAAAATGCAATTCCCTAATCCAAATGAATAC
AGCGCATTCATGGGAACATTCTCTTTCTGGACAGGGGTTGTATCCGTATTCGTTATGCTGTTCATTGGTGGTAATGTTAT
CCGTCGTTTTGGCTGGTTAACAGGCGCCTTAGTTACACCTGTCATGGTCCTCGTAACAGGAGCGATCTTCTTTGCTCTCG
TTATCTTCAGAGATCATGCAACAGGATTGGTTGCAGCTTTGGGAACAACTCCTTTAATGCTAGCGGTTGTTGTTGGAGCC
GTCCAAAATATTCTTTCCAAATCGACTAAATATGCTCTCTTTGATGCAACTAAAGAGATGGCTTACATCCCATTGGATCA
AGAGCAAAAAGTTAAAGGAAAAGCCGCTATTGACGTTGTTGCTGCTAGATTTGGTAAATCTGGGGGATCTTTGATCCAAC
AAGGACTCCTAGTTGTTTGCGGAAGCATCAGTGCGATGACTCCATTCCTAGCGGTAGCTCTCTTTGCAATTATTATGGTT
TGGTTAACATCTGCAACCAAACTTAATAAATTGTTCTTAGCTGCTTCAGCTGCTAAAGAACAAGAGCTGGCAGAGGCCAC
AGCAGCAGCTGAGAAGGAAGCTTCTCCTGCAGCGAAAGAAGTCTCTCCTGCTATAGAGGGTGTTTCCTAA

Upstream 100 bases:

>100_bases
TTATTGTTTTACAATCTGCTCAAAAAGATACTTTAAAATTCGTTGACCTAGTCAACAAAGAAAACTTAACAATAAACATA
AGCTTTTCAGAGGGTGAAAT

Downstream 100 bases:

>100_bases
CATCATTTTTCTAGAAACTTTCTAGTAAAAAGAGGGCCCCGCTTATTTTGAGCGGGGCTTTTCTTTTGTCTTTAAAATCT
CTTTTCTTCACAAATCTCTT

Product: ADP, ATP carrier protein

Products: NA

Alternate protein names: ADP/ATP translocase 1

Number of amino acids: Translated: 529; Mature: 528

Protein sequence:

>529_residues
MTQTAEKPFGKLRSFLWPIHMHELKKVLPMFLMFFCISFNYTILRDTKDTLIVTAPGSGAEAIPFIKLWLVVPSAVVFML
IYAKLSNILSKQALFYAVLSPFVVFFALFPLVIYPYRHILHPTDFADTLQAILPSGFLGFIAMLRNWTFAAFYVLSELWG
SVMLSLMFWGFANEITKISEAKRFYALFGVGANVALLISGPAIVWSSKLRASLGEGVDPWGVTLYFLMAMFLCSCAIIAA
CYWWMNRYVLTDPRFYNPAELKAKKSKPKMSMGESFSYLLRSPYMLLLALLVICYGVCINLVEVTWKSQLKMQFPNPNEY
SAFMGTFSFWTGVVSVFVMLFIGGNVIRRFGWLTGALVTPVMVLVTGAIFFALVIFRDHATGLVAALGTTPLMLAVVVGA
VQNILSKSTKYALFDATKEMAYIPLDQEQKVKGKAAIDVVAARFGKSGGSLIQQGLLVVCGSISAMTPFLAVALFAIIMV
WLTSATKLNKLFLAASAAKEQELAEATAAAEKEASPAAKEVSPAIEGVS

Sequences:

>Translated_529_residues
MTQTAEKPFGKLRSFLWPIHMHELKKVLPMFLMFFCISFNYTILRDTKDTLIVTAPGSGAEAIPFIKLWLVVPSAVVFML
IYAKLSNILSKQALFYAVLSPFVVFFALFPLVIYPYRHILHPTDFADTLQAILPSGFLGFIAMLRNWTFAAFYVLSELWG
SVMLSLMFWGFANEITKISEAKRFYALFGVGANVALLISGPAIVWSSKLRASLGEGVDPWGVTLYFLMAMFLCSCAIIAA
CYWWMNRYVLTDPRFYNPAELKAKKSKPKMSMGESFSYLLRSPYMLLLALLVICYGVCINLVEVTWKSQLKMQFPNPNEY
SAFMGTFSFWTGVVSVFVMLFIGGNVIRRFGWLTGALVTPVMVLVTGAIFFALVIFRDHATGLVAALGTTPLMLAVVVGA
VQNILSKSTKYALFDATKEMAYIPLDQEQKVKGKAAIDVVAARFGKSGGSLIQQGLLVVCGSISAMTPFLAVALFAIIMV
WLTSATKLNKLFLAASAAKEQELAEATAAAEKEASPAAKEVSPAIEGVS
>Mature_528_residues
TQTAEKPFGKLRSFLWPIHMHELKKVLPMFLMFFCISFNYTILRDTKDTLIVTAPGSGAEAIPFIKLWLVVPSAVVFMLI
YAKLSNILSKQALFYAVLSPFVVFFALFPLVIYPYRHILHPTDFADTLQAILPSGFLGFIAMLRNWTFAAFYVLSELWGS
VMLSLMFWGFANEITKISEAKRFYALFGVGANVALLISGPAIVWSSKLRASLGEGVDPWGVTLYFLMAMFLCSCAIIAAC
YWWMNRYVLTDPRFYNPAELKAKKSKPKMSMGESFSYLLRSPYMLLLALLVICYGVCINLVEVTWKSQLKMQFPNPNEYS
AFMGTFSFWTGVVSVFVMLFIGGNVIRRFGWLTGALVTPVMVLVTGAIFFALVIFRDHATGLVAALGTTPLMLAVVVGAV
QNILSKSTKYALFDATKEMAYIPLDQEQKVKGKAAIDVVAARFGKSGGSLIQQGLLVVCGSISAMTPFLAVALFAIIMVW
LTSATKLNKLFLAASAAKEQELAEATAAAEKEASPAAKEVSPAIEGVS

Specific function: Unknown

COG id: COG3202

COG function: function code C; ATP/ADP translocase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ADP/ATP translocase tlc family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): TLC1_CHLMU (Q9PKX5)

Other databases:

- EMBL:   AE002160
- PIR:   C81714
- RefSeq:   NP_296714.1
- GeneID:   1246379
- GenomeReviews:   AE002160_GR
- KEGG:   cmu:TC0335
- TIGR:   TC_0335
- HOGENOM:   HBG586333
- OMA:   AYPNFKW
- ProtClustDB:   CLSK870724
- BioCyc:   CMUR243161:TC_0335-MONOMER
- InterPro:   IPR004667
- TIGRFAMs:   TIGR00769

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 58305; Mature: 58174

Theoretical pI: Translated: 9.58; Mature: 9.58

Prosite motif: PS00430 TONB_DEPENDENT_REC_1

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xbf319f8)-; HASH(0xc5ebd90)-; HASH(0xca55624)-; HASH(0xca15764)-; HASH(0xb2b87f0)-; HASH(0xca1ff44)-; HASH(0xb9019e8)-; HASH(0xbbdc4dc)-; HASH(0xc9add10)-; HASH(0xc9f7698)-; HASH(0xc50a154)-; HASH(0xca3fd9c)-;

Cys/Met content:

1.3 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCH
>Mature Secondary Structure 
TQTAEKPFGKLRSFLWPIHMHELKKVLPMFLMFFCISFNYTILRDTKDTLIVTAPGSGA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCEEEEECCCCCC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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10684935