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The map label for this gene is ruvB

Identifier: 15834930

GI number: 15834930

Start: 365993

End: 366985

Strand: Direct

Name: ruvB

Synonym: TC0310

Alternate gene names: 15834930

Gene position: 365993-366985 (Clockwise)

Preceding gene: 15834925

Following gene: 15834931

Centisome position: 34.11

GC content: 41.99

Gene sequence:

>993_bases
ATGACTCATAAAATTTCTGTTTTACACCAAGATAAAAAATTCGATTTTTCTTTGAGGCCAAAAAAGCTAACAGAGTTTTA
CGGGCAAAAACAGCTAAAAGAACGACTAGATCTTTTTCTTCGCGCAGCAGTTCAACGGAAGGAGGTCCCTGGCCATTGTT
TGTTTTACGGCCCTCCAGGATTAGGGAAAACTTCATTAGCACACATTATGGCGAATACAGTAGGAAAAGGTCTAGTAATC
GCTTCTGGTCCCCAGTTATTGAAACCATCTGATCTTATAGGACTATTGACTGGGTTACAAGAGGGTGATGTATTTTTCAT
TGATGAGATCCATCGCATGGGGAAAACTGCTGAAGAGTATCTGTATCCGGCAATGGAAGATTTTAAAGTGGATATTACTT
TAGATTCTGGTCCAGGGGCACGTTCCGTACGTCTTGATTTGGCTCCTTTCACTCTAGTTGGTGCGACTACTCGTGCAGGA
ATGTTGAGTGAACCTTTGCGCACACGTTTTGCTTTTACTGGACGAGTAGATTACTATAACGAGGAAGATTTGGTTGCAAT
TCTATCTCGCTCTGCGCAGTTGCTTTCTATAGAAGCAAATAAGGAAACTCTTCTAGAGATTGCTAGAAGAGCACGCGGGA
CTCCACGTTTAGCGAATAATTTGCTTCGATGGGTTCGGGATTTTGCACAAATGCGAGAGGGAAATTGTATTAATAGCGTC
GTAGCAGAAAAAGCTTTAGCTATGTTATTAATAGATAACTTAGGGTTAAACGAGATTGACATTAAACTTCTCTCCGTGAT
GATTGATTTTTATCAAGGGGGCCCTGTTGGGATGAAAACGCTTGCAATGGCTGTAGGCGAGGATGTCAGGACTCTGGAAG
ATATGTACGAACCCTTTTTGATTTTAAAAGGATTGGTTCAACGAACCGCGAGAGGGCGGGTTGCAACTCCTTTGGCATAT
GAACATCTTAACAGGAACCCAAAGGACAAGTAG

Upstream 100 bases:

>100_bases
ATAGGTCAAGGTATTTCCTAATAGTCTTGGGAATACCTTGACTTCGGTTATTATGGGATGTCAAAATAAGATTTCTCGAC
GTTAGTTAACGAATAAATCT

Downstream 100 bases:

>100_bases
GGAGAAGAAGAAAGTGAAAAAGTTAAATCTACTCGTGCTGTTAGGAGTGTTTTGTGGGGTGGGGGCTGTTGGAGATGCCG
ATGTTAAGGTATCTGATGCC

Product: Holliday junction DNA helicase RuvB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 330; Mature: 329

Protein sequence:

>330_residues
MTHKISVLHQDKKFDFSLRPKKLTEFYGQKQLKERLDLFLRAAVQRKEVPGHCLFYGPPGLGKTSLAHIMANTVGKGLVI
ASGPQLLKPSDLIGLLTGLQEGDVFFIDEIHRMGKTAEEYLYPAMEDFKVDITLDSGPGARSVRLDLAPFTLVGATTRAG
MLSEPLRTRFAFTGRVDYYNEEDLVAILSRSAQLLSIEANKETLLEIARRARGTPRLANNLLRWVRDFAQMREGNCINSV
VAEKALAMLLIDNLGLNEIDIKLLSVMIDFYQGGPVGMKTLAMAVGEDVRTLEDMYEPFLILKGLVQRTARGRVATPLAY
EHLNRNPKDK

Sequences:

>Translated_330_residues
MTHKISVLHQDKKFDFSLRPKKLTEFYGQKQLKERLDLFLRAAVQRKEVPGHCLFYGPPGLGKTSLAHIMANTVGKGLVI
ASGPQLLKPSDLIGLLTGLQEGDVFFIDEIHRMGKTAEEYLYPAMEDFKVDITLDSGPGARSVRLDLAPFTLVGATTRAG
MLSEPLRTRFAFTGRVDYYNEEDLVAILSRSAQLLSIEANKETLLEIARRARGTPRLANNLLRWVRDFAQMREGNCINSV
VAEKALAMLLIDNLGLNEIDIKLLSVMIDFYQGGPVGMKTLAMAVGEDVRTLEDMYEPFLILKGLVQRTARGRVATPLAY
EHLNRNPKDK
>Mature_329_residues
THKISVLHQDKKFDFSLRPKKLTEFYGQKQLKERLDLFLRAAVQRKEVPGHCLFYGPPGLGKTSLAHIMANTVGKGLVIA
SGPQLLKPSDLIGLLTGLQEGDVFFIDEIHRMGKTAEEYLYPAMEDFKVDITLDSGPGARSVRLDLAPFTLVGATTRAGM
LSEPLRTRFAFTGRVDYYNEEDLVAILSRSAQLLSIEANKETLLEIARRARGTPRLANNLLRWVRDFAQMREGNCINSVV
AEKALAMLLIDNLGLNEIDIKLLSVMIDFYQGGPVGMKTLAMAVGEDVRTLEDMYEPFLILKGLVQRTARGRVATPLAYE
HLNRNPKDK

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG2255

COG function: function code L; Holliday junction resolvasome, helicase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvB family [H]

Homologues:

Organism=Escherichia coli, GI1788167, Length=315, Percent_Identity=50.1587301587302, Blast_Score=324, Evalue=6e-90,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR004605
- InterPro:   IPR008823
- InterPro:   IPR011991
- ProDom:   PD005323 [H]

Pfam domain/function: PF00004 AAA; PF05491 RuvB_C [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 36875; Mature: 36744

Theoretical pI: Translated: 9.21; Mature: 9.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHKISVLHQDKKFDFSLRPKKLTEFYGQKQLKERLDLFLRAAVQRKEVPGHCLFYGPPG
CCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCC
LGKTSLAHIMANTVGKGLVIASGPQLLKPSDLIGLLTGLQEGDVFFIDEIHRMGKTAEEY
CCHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHCCCCCCEEEHHHHHHHCCCHHHH
LYPAMEDFKVDITLDSGPGARSVRLDLAPFTLVGATTRAGMLSEPLRTRFAFTGRVDYYN
HCCCHHCEEEEEEECCCCCCCEEEEEECCEEEECCCHHCCHHHHHHHHHHEEECEECCCC
EEDLVAILSRSAQLLSIEANKETLLEIARRARGTPRLANNLLRWVRDFAQMREGNCINSV
CCHHHHHHHCCCEEEEEECCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHH
VAEKALAMLLIDNLGLNEIDIKLLSVMIDFYQGGPVGMKTLAMAVGEDVRTLEDMYEPFL
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCHHHHHHHHHHHHHH
ILKGLVQRTARGRVATPLAYEHLNRNPKDK
HHHHHHHHHHCCCCCCHHHHHHCCCCCCCC
>Mature Secondary Structure 
THKISVLHQDKKFDFSLRPKKLTEFYGQKQLKERLDLFLRAAVQRKEVPGHCLFYGPPG
CCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCC
LGKTSLAHIMANTVGKGLVIASGPQLLKPSDLIGLLTGLQEGDVFFIDEIHRMGKTAEEY
CCHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHCCCCCCEEEHHHHHHHCCCHHHH
LYPAMEDFKVDITLDSGPGARSVRLDLAPFTLVGATTRAGMLSEPLRTRFAFTGRVDYYN
HCCCHHCEEEEEEECCCCCCCEEEEEECCEEEECCCHHCCHHHHHHHHHHEEECEECCCC
EEDLVAILSRSAQLLSIEANKETLLEIARRARGTPRLANNLLRWVRDFAQMREGNCINSV
CCHHHHHHHCCCEEEEEECCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHH
VAEKALAMLLIDNLGLNEIDIKLLSVMIDFYQGGPVGMKTLAMAVGEDVRTLEDMYEPFL
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCHHHHHHHHHHHHHH
ILKGLVQRTARGRVATPLAYEHLNRNPKDK
HHHHHHHHHHCCCCCCHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA