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The map label for this gene is ffh

Identifier: 15834914

GI number: 15834914

Start: 352090

End: 353436

Strand: Direct

Name: ffh

Synonym: TC0294

Alternate gene names: 15834914

Gene position: 352090-353436 (Clockwise)

Preceding gene: 15834913

Following gene: 15834915

Centisome position: 32.82

GC content: 42.39

Gene sequence:

>1347_bases
ATGATTAATTCTTTATCGCAAAAATTATCTAGTATTTTCTCCTCACTTTTTACTGCAAAGAGAGTAACAGAGGAGAGTAT
TTCTGATTCCATTAGAGAAATTCGCCTAGCTCTTCTAGATGCTGATGTGAATTATCAGGCGGTGAAAGATTTTATATCCA
AGGTAAAGCAGAAAGTCATTGGGGAAGAGGTCTGGAAACACGTATCCCCAGGACAACAGTTTGTGAAATGTTTGCATGAA
GAGCTTGCGGCTTTGCTTTCTTCACAACAGGCTAGTTTATTGTTGCAGGGGCGTCCTGCGGTTGTTTTATTTTGTGGATT
GCAGGGAGCGGGTAAGACGACTACATGTGCCAAGCTTGCCGACTACGTTCTTCGAGAGAAGAAAGCAAAAAAAGTGTTAG
TGGCTTCTTGTGATTTAAAGCGTTTTTCAGCAGTGGACCAGCTGGAGGGCTTAATAAAGCAAACTGGGGCAGATTTTTTC
CGAAAAAAAGGAGAAAATCCTGTGAGTATGGCATCAGAGGCGGTTCGCTACGCAAAGGATCAAGGTTATGATTTATTAAT
CGTTGATACTGCTGGTCGACTTCATGTGGATGATGCATTGATGGATGAGCTGGTGGCCATTGCTCGTGTAACGAATCCGT
CCGAAATCTTATTCGTTATGAATTTAGCGATGGGCCAGGATGCAGTAACTACTGCGAAGGCTTTTGATGAGCGCTTAGGG
TTAACTGGTATCGTCGTGTCCATGGCAGATGGCGATGCTCGGGCTGGAGCAGTCTTATCAGTGAAGTCTTTGCTTGGCAG
ACCTATTAAATTTGAAGGGTGTGGGGAAAAAATAAAAGATCTACGTCCTTTTAACGCACAGTCTATGGCTGAACGTATCC
TAGGAATGGGAGATACAATAAGTTTAGTTGATAAGATGCGTGAGTGTGTCTCTGAAGAAGAGAACAAAGAGTTAGAAGAA
AAATTAACGAAAGCGACGTTTACTTATGAGGATTTTTATAAGCAAATGCGAGCTTTCCGTCGTTTAGGGCCTTTGCGCAA
AATCATGAATATGATGCCAAGCTTCGGTGGCATGAGGCCTAGTGATAAGGATTTGGAAGAATCCGAGAAGCAAATGAAAA
GAAATGAGGCGATTATTCTTTCTATGACTCCAGAGGAAAGGAAGGAGTTGGTCGAACTGAATATGAGCCGGATGAAAAGA
ATCGCTGCGGGCTGTGGCCTGACTTTAGGTGATGTAAATCAGTTCCGTAAGCAAATGATGCAATCTAAGAAATTTTTTAA
AGGGATGACCCGAGAAAAAATGGAACAGATGGGTAAAAAAATGTCTGGAGGGAATCTGTGGCGTTAA

Upstream 100 bases:

>100_bases
GTGTATTCAAAGATTACGCTCAGTTAGATAGGTTTTTTTTCCTTGAAAATCAAGCTGGTGATGCTGTATCCTCTGGGGAG
GTTTCTGGCTTTTCCGAGAG

Downstream 100 bases:

>100_bases
AAATTCGTTTAAGACAACAAGGACGCAAGAACCATGTTGTATATAGATTAGTACTAGCTGATGTAGAATCTCCTAGAGAT
GGTAAATATATCGAGTTGTT

Product: signal recognition particle

Products: NA

Alternate protein names: Fifty-four homolog [H]

Number of amino acids: Translated: 448; Mature: 448

Protein sequence:

>448_residues
MINSLSQKLSSIFSSLFTAKRVTEESISDSIREIRLALLDADVNYQAVKDFISKVKQKVIGEEVWKHVSPGQQFVKCLHE
ELAALLSSQQASLLLQGRPAVVLFCGLQGAGKTTTCAKLADYVLREKKAKKVLVASCDLKRFSAVDQLEGLIKQTGADFF
RKKGENPVSMASEAVRYAKDQGYDLLIVDTAGRLHVDDALMDELVAIARVTNPSEILFVMNLAMGQDAVTTAKAFDERLG
LTGIVVSMADGDARAGAVLSVKSLLGRPIKFEGCGEKIKDLRPFNAQSMAERILGMGDTISLVDKMRECVSEEENKELEE
KLTKATFTYEDFYKQMRAFRRLGPLRKIMNMMPSFGGMRPSDKDLEESEKQMKRNEAIILSMTPEERKELVELNMSRMKR
IAAGCGLTLGDVNQFRKQMMQSKKFFKGMTREKMEQMGKKMSGGNLWR

Sequences:

>Translated_448_residues
MINSLSQKLSSIFSSLFTAKRVTEESISDSIREIRLALLDADVNYQAVKDFISKVKQKVIGEEVWKHVSPGQQFVKCLHE
ELAALLSSQQASLLLQGRPAVVLFCGLQGAGKTTTCAKLADYVLREKKAKKVLVASCDLKRFSAVDQLEGLIKQTGADFF
RKKGENPVSMASEAVRYAKDQGYDLLIVDTAGRLHVDDALMDELVAIARVTNPSEILFVMNLAMGQDAVTTAKAFDERLG
LTGIVVSMADGDARAGAVLSVKSLLGRPIKFEGCGEKIKDLRPFNAQSMAERILGMGDTISLVDKMRECVSEEENKELEE
KLTKATFTYEDFYKQMRAFRRLGPLRKIMNMMPSFGGMRPSDKDLEESEKQMKRNEAIILSMTPEERKELVELNMSRMKR
IAAGCGLTLGDVNQFRKQMMQSKKFFKGMTREKMEQMGKKMSGGNLWR
>Mature_448_residues
MINSLSQKLSSIFSSLFTAKRVTEESISDSIREIRLALLDADVNYQAVKDFISKVKQKVIGEEVWKHVSPGQQFVKCLHE
ELAALLSSQQASLLLQGRPAVVLFCGLQGAGKTTTCAKLADYVLREKKAKKVLVASCDLKRFSAVDQLEGLIKQTGADFF
RKKGENPVSMASEAVRYAKDQGYDLLIVDTAGRLHVDDALMDELVAIARVTNPSEILFVMNLAMGQDAVTTAKAFDERLG
LTGIVVSMADGDARAGAVLSVKSLLGRPIKFEGCGEKIKDLRPFNAQSMAERILGMGDTISLVDKMRECVSEEENKELEE
KLTKATFTYEDFYKQMRAFRRLGPLRKIMNMMPSFGGMRPSDKDLEESEKQMKRNEAIILSMTPEERKELVELNMSRMKR
IAAGCGLTLGDVNQFRKQMMQSKKFFKGMTREKMEQMGKKMSGGNLWR

Specific function: Necessary for efficient export of extracytoplasmic proteins. Binds to the signal sequence when it emerges from the ribosomes [H]

COG id: COG0541

COG function: function code U; Signal recognition particle GTPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding SRP family [H]

Homologues:

Organism=Homo sapiens, GI4507215, Length=446, Percent_Identity=33.1838565022422, Blast_Score=232, Evalue=5e-61,
Organism=Homo sapiens, GI226371618, Length=354, Percent_Identity=34.4632768361582, Blast_Score=203, Evalue=2e-52,
Organism=Homo sapiens, GI23308697, Length=304, Percent_Identity=29.9342105263158, Blast_Score=120, Evalue=3e-27,
Organism=Homo sapiens, GI295424842, Length=304, Percent_Identity=29.9342105263158, Blast_Score=120, Evalue=4e-27,
Organism=Homo sapiens, GI89061728, Length=157, Percent_Identity=37.5796178343949, Blast_Score=119, Evalue=8e-27,
Organism=Escherichia coli, GI1788963, Length=421, Percent_Identity=45.3681710213777, Blast_Score=360, Evalue=1e-100,
Organism=Escherichia coli, GI1789874, Length=300, Percent_Identity=32.6666666666667, Blast_Score=148, Evalue=6e-37,
Organism=Caenorhabditis elegans, GI17539958, Length=428, Percent_Identity=30.1401869158879, Blast_Score=206, Evalue=2e-53,
Organism=Caenorhabditis elegans, GI193206261, Length=311, Percent_Identity=29.5819935691318, Blast_Score=125, Evalue=5e-29,
Organism=Saccharomyces cerevisiae, GI6325345, Length=428, Percent_Identity=31.0747663551402, Blast_Score=196, Evalue=5e-51,
Organism=Saccharomyces cerevisiae, GI6320498, Length=214, Percent_Identity=31.7757009345794, Blast_Score=96, Evalue=1e-20,
Organism=Drosophila melanogaster, GI17647949, Length=353, Percent_Identity=33.9943342776204, Blast_Score=210, Evalue=2e-54,
Organism=Drosophila melanogaster, GI24641198, Length=319, Percent_Identity=26.6457680250784, Blast_Score=120, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR000897
- InterPro:   IPR013822
- InterPro:   IPR004780
- InterPro:   IPR004125 [H]

Pfam domain/function: PF00448 SRP54; PF02881 SRP54_N; PF02978 SRP_SPB [H]

EC number: NA

Molecular weight: Translated: 50065; Mature: 50065

Theoretical pI: Translated: 9.44; Mature: 9.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
5.4 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
5.4 %Met     (Mature Protein)
6.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINSLSQKLSSIFSSLFTAKRVTEESISDSIREIRLALLDADVNYQAVKDFISKVKQKVI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
GEEVWKHVSPGQQFVKCLHEELAALLSSQQASLLLQGRPAVVLFCGLQGAGKTTTCAKLA
HHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHEECCCCEEEEEECCCCCCCCHHHHHHH
DYVLREKKAKKVLVASCDLKRFSAVDQLEGLIKQTGADFFRKKGENPVSMASEAVRYAKD
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCHHHHHHCCCCHHHHHHHHHHHHHC
QGYDLLIVDTAGRLHVDDALMDELVAIARVTNPSEILFVMNLAMGQDAVTTAKAFDERLG
CCCEEEEEECCCCEEHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHCC
LTGIVVSMADGDARAGAVLSVKSLLGRPIKFEGCGEKIKDLRPFNAQSMAERILGMGDTI
CHHEEEEECCCCCCCHHHHHHHHHHCCCCEECCCCHHHHHCCCCCHHHHHHHHHCCCCHH
SLVDKMRECVSEEENKELEEKLTKATFTYEDFYKQMRAFRRLGPLRKIMNMMPSFGGMRP
HHHHHHHHHHCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
SDKDLEESEKQMKRNEAIILSMTPEERKELVELNMSRMKRIAAGCGLTLGDVNQFRKQMM
CCCCHHHHHHHHHHCCEEEEEECHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
QSKKFFKGMTREKMEQMGKKMSGGNLWR
HHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MINSLSQKLSSIFSSLFTAKRVTEESISDSIREIRLALLDADVNYQAVKDFISKVKQKVI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
GEEVWKHVSPGQQFVKCLHEELAALLSSQQASLLLQGRPAVVLFCGLQGAGKTTTCAKLA
HHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHEECCCCEEEEEECCCCCCCCHHHHHHH
DYVLREKKAKKVLVASCDLKRFSAVDQLEGLIKQTGADFFRKKGENPVSMASEAVRYAKD
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCHHHHHHCCCCHHHHHHHHHHHHHC
QGYDLLIVDTAGRLHVDDALMDELVAIARVTNPSEILFVMNLAMGQDAVTTAKAFDERLG
CCCEEEEEECCCCEEHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHCC
LTGIVVSMADGDARAGAVLSVKSLLGRPIKFEGCGEKIKDLRPFNAQSMAERILGMGDTI
CHHEEEEECCCCCCCHHHHHHHHHHCCCCEECCCCHHHHHCCCCCHHHHHHHHHCCCCHH
SLVDKMRECVSEEENKELEEKLTKATFTYEDFYKQMRAFRRLGPLRKIMNMMPSFGGMRP
HHHHHHHHHHCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
SDKDLEESEKQMKRNEAIILSMTPEERKELVELNMSRMKRIAAGCGLTLGDVNQFRKQMM
CCCCHHHHHHHHHHCCEEEEEECHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
QSKKFFKGMTREKMEQMGKKMSGGNLWR
HHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]