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The map label for this gene is ileS

Identifier: 15834908

GI number: 15834908

Start: 343596

End: 346706

Strand: Direct

Name: ileS

Synonym: TC0288

Alternate gene names: 15834908

Gene position: 343596-346706 (Clockwise)

Preceding gene: 15834907

Following gene: 15834911

Centisome position: 32.02

GC content: 41.18

Gene sequence:

>3111_bases
ATGGATAACGAAGATAAGGTGAGTTTTCCCGCCAAAGAGGAAAAGGTTCTAACTTTTTGGAAAGAACAAAACATTTTTCA
AAAAACTTTAGAAAATCGAGATGGGAGCCCCACTTTTTCTTTTTATGATGGGCCTCCATTTGCGACGGGATTACCCCATT
ATGGCCATTTATTAGCTGGCACAATTAAAGATGTTGTATGTCGTTATGCTACGATGGATGGGCATTATGTGCCTCGACGC
TTTGGTTGGGATTGCCATGGGGTTCCCGTTGAGTATGAAGTGGAGAAATCATTAGGTTTAACGGAACCTGGAGCTATTGA
TCGGTTTGGTATAGCTAACTTTAATGAAGAGTGCCGTAAGATTGTTTTTCGATACGTCGATGAATGGAAATATTTTGTAG
ATAGAATTGGACGATGGGTTGATTTTTCAGCAACGTGGAAGACTATGGACCTATCTTTCATGGAAAGTGTTTGGTGGGTA
TTCCATTCTCTTTATAAACAGGGGCTTGTGTATGAAGGGACGAAGGTTGTTCCCTTTTCTACCAAACTAGGGACTCCGCT
GTCTAATTTCGAAGCTGGTCAAAATTATAAAGAGGTGGATGATCCATCTGTTGTTGCGAAGTTTGCCTTGCAAGATGATC
AGGGCATTCTTTTAGCATGGACAACAACTCCTTGGACGCTTGTTTCGAATATGGCTTTGGCTGTGCATCCAGGACTTACC
TATGTCCGTATTCAAGACAAGGAATCAGGAGAAGAGTACATTCTTGGTCAAGAAAGTCTGGCTCGTTGGTTCCCTGATCG
GGAATCCTATAAATGGATAGGACAATTGTCTGGGGAAAGCCTTGTTGGTCGAAGATACTGTCCTTTGTTCCCTTATTTCC
AGGATCAACAGGATCGGGGAGCTTTTCGTGTTATTCCTGCAGACTTTATCGAAGAAAGTGAAGGGACTGGTGTTGTTCAC
ATGGCTCCAGCTTTCGGAGAAGCAGACTTTTTTGCTTGCCAGGAACATAATGTGCCTTTGGTATGTCCTGTTGATAACCA
AGGGTGTTTTACTTCTGAAGTGACTGATTTTGTCGGAGAATACATTAAGTTTGCAGATAAGGGAATTGCTCGTCGGTTGA
AGAATGAAAATAAATTGTTCTATCAAGGCACTATTCGTCACCGTTATCCATTTTGTTGGAGAACAGATTCTCCATTAATC
TACAAAGCAGTTAATTCTTGGTTTGTCTCTGTAGAAAAAGTAAAACACAAAATGCTGAAAGCCAATGAATCGATTCATTG
GACTCCGGGACATATCAAGCACGGGCGTTTTGGTAAATGGCTTGAGGGGGCTCGTGATTGGGCCATTAGCAGAAATCGTT
ACTGGGGAACGCCTATACCTATCTGGCGTAGTGAAGATGGGGAGCTTCTTGTCATAAGGTCTATCCAGGAGCTAGAAGAA
TTATCTGGGCAGAAGATTGTTGATTTACATCGTCATTTTATTGATGAGATTGTCATTCATAAAAATGGAAAAAGTTTCCA
TAGAATTCCTTATGTTTTTGATTGTTGGTTTGATTCTGGGGCAATGCCTTATGCCCAAAACCATTATCCTTTTGAACGTG
CCGAAGAAACTGAAGCGCGTTTCCCAGCAGATTTCATTGCTGAAGGGCTTGATCAGACTCGGGGCTGGTTTTATACTTTA
ACTGTAATTGCTGCAGCTTTGTTTGATCAACCAGCTTTTAAGAACGTAATTGTGAATGGAATTGTTCTTGCTGAAGACGG
AAATAAAATGTCTAAGCGACTGAATAATTATCCAAGTCCTAAAAAAATTATGGATACGTATGGTGCGGATGCTTTGCGCC
TGTATTTGTTGAATAGTGTCGTTGTCAAAGCCGAAGATTTAAGGTTCTCTGACAAAGGGGTGGAGGCTGTACTCAAGCAA
GTGCTTTTACCTTTGTCTAATGCTTTGGCTTTTTACAAGACTTATGCAGAGTTGTATGGTTTTTCTCCAAATGAAACAAC
AGACTTAGAGCTTGCTGAGATAGATCGCTGGATTCTTTCTTCTTTGTATAGCTTAGTAGGGAAAACTAGGGAAAACATGG
CGCAGTATGATTTACATGCCGCAGTAAGTCCCTTTATAGATTTCATTGAGGATCTAACAAATTGGTACATTCGTCGATCA
CGTCGGCGCTTCTGGGAATCAGAGGATTCTCCAGACCGTCGAGCTGCTTTTGCTACCCTTTATGAAGTACTGATGGTTTT
TTCTAAGATTATAGCTCCGTTCATTCCTTTTACTGCTGAGGATATGTATCAGCAATTGCGGGTTGAAACGGATCCTGAAT
CTGTGCATTTGTGTGATTTCCCTCACGTTGTTTTGGAAAAAATCCTTCCTGATTTAGAAAAGAAGATGCAAGACATTCGG
GAGATCGTTGCTTTAGGACATTCTCTACGTAAAGAACATAAGCTTAAAGTTCGACAGCCACTTCAACATATGTATATTGT
CGGTGCTAAAGAACGAATGGCTGCGTTGGCTCAAGTTGACTCATTGATTGGAGAGGAGTTGAATGTTAAGGAAGTGCATT
TTTGCTCAGAGACTCCAGAATATGTGACTACTCTTGTTAAGCCCAATTTCCGTTCTCTAGGAAAAAGGGTTGGGAATCGT
CTCCCCGAAATTCAAAAGGCTTTGGCAGGACTTTCTCAAGAGCAAATTCAAGCGTTTATGCATAATGGCTTTATGGTTCT
TTCTTTAGGAGAAGAAACGATTTCTCTAAATGAAGAGGATATTACCGTGTCCTGGGAAGCCGCTCCGGGGTTTGTAGCAA
GAAGCTCAGCCTCTTTTGTAGCGATTTTAGATTGTCAACTAACTTCTCCTCTGATTATGGAAGGGATAGCCAGAGAAATT
GTAAATAAGATCAATACTATGCGAAGAAATGGGAAATTACACGTTTCGGATCGTATTGCTATACGTTTGCATGCTCCTAA
AATTGTTCAGGAAGCTTTTTCTCAATATGAAGAATATATTTGCGAAGAGACATTAACAACTTCGGTTTCCTTTATAGATG
ACAAGGAGGGAGAGGAGTGGGATGTTAACGGTCACGCGGTCTCACTGTCCCTAGAGGTGATTGGTCATTGA

Upstream 100 bases:

>100_bases
CCAATAAGACTGTTTCGGAAAGCTGTCAAACTGCAAACCTTATGAGCAGAATAATAATGCCTTCCAGTATCAAAAACCAA
AGTGAATCATCGAAGAAATA

Downstream 100 bases:

>100_bases
GATGACATATAAAAGAGGTCCTATAGGACCTCTTTTTTTTGTTATTTGTTAGGGGAATAACCTGTGATTCTTTCGATAAT
ACCACGCACCCACAAAGTAA

Product: isoleucyl-tRNA synthetase

Products: NA

Alternate protein names: Isoleucine--tRNA ligase; IleRS

Number of amino acids: Translated: 1036; Mature: 1036

Protein sequence:

>1036_residues
MDNEDKVSFPAKEEKVLTFWKEQNIFQKTLENRDGSPTFSFYDGPPFATGLPHYGHLLAGTIKDVVCRYATMDGHYVPRR
FGWDCHGVPVEYEVEKSLGLTEPGAIDRFGIANFNEECRKIVFRYVDEWKYFVDRIGRWVDFSATWKTMDLSFMESVWWV
FHSLYKQGLVYEGTKVVPFSTKLGTPLSNFEAGQNYKEVDDPSVVAKFALQDDQGILLAWTTTPWTLVSNMALAVHPGLT
YVRIQDKESGEEYILGQESLARWFPDRESYKWIGQLSGESLVGRRYCPLFPYFQDQQDRGAFRVIPADFIEESEGTGVVH
MAPAFGEADFFACQEHNVPLVCPVDNQGCFTSEVTDFVGEYIKFADKGIARRLKNENKLFYQGTIRHRYPFCWRTDSPLI
YKAVNSWFVSVEKVKHKMLKANESIHWTPGHIKHGRFGKWLEGARDWAISRNRYWGTPIPIWRSEDGELLVIRSIQELEE
LSGQKIVDLHRHFIDEIVIHKNGKSFHRIPYVFDCWFDSGAMPYAQNHYPFERAEETEARFPADFIAEGLDQTRGWFYTL
TVIAAALFDQPAFKNVIVNGIVLAEDGNKMSKRLNNYPSPKKIMDTYGADALRLYLLNSVVVKAEDLRFSDKGVEAVLKQ
VLLPLSNALAFYKTYAELYGFSPNETTDLELAEIDRWILSSLYSLVGKTRENMAQYDLHAAVSPFIDFIEDLTNWYIRRS
RRRFWESEDSPDRRAAFATLYEVLMVFSKIIAPFIPFTAEDMYQQLRVETDPESVHLCDFPHVVLEKILPDLEKKMQDIR
EIVALGHSLRKEHKLKVRQPLQHMYIVGAKERMAALAQVDSLIGEELNVKEVHFCSETPEYVTTLVKPNFRSLGKRVGNR
LPEIQKALAGLSQEQIQAFMHNGFMVLSLGEETISLNEEDITVSWEAAPGFVARSSASFVAILDCQLTSPLIMEGIAREI
VNKINTMRRNGKLHVSDRIAIRLHAPKIVQEAFSQYEEYICEETLTTSVSFIDDKEGEEWDVNGHAVSLSLEVIGH

Sequences:

>Translated_1036_residues
MDNEDKVSFPAKEEKVLTFWKEQNIFQKTLENRDGSPTFSFYDGPPFATGLPHYGHLLAGTIKDVVCRYATMDGHYVPRR
FGWDCHGVPVEYEVEKSLGLTEPGAIDRFGIANFNEECRKIVFRYVDEWKYFVDRIGRWVDFSATWKTMDLSFMESVWWV
FHSLYKQGLVYEGTKVVPFSTKLGTPLSNFEAGQNYKEVDDPSVVAKFALQDDQGILLAWTTTPWTLVSNMALAVHPGLT
YVRIQDKESGEEYILGQESLARWFPDRESYKWIGQLSGESLVGRRYCPLFPYFQDQQDRGAFRVIPADFIEESEGTGVVH
MAPAFGEADFFACQEHNVPLVCPVDNQGCFTSEVTDFVGEYIKFADKGIARRLKNENKLFYQGTIRHRYPFCWRTDSPLI
YKAVNSWFVSVEKVKHKMLKANESIHWTPGHIKHGRFGKWLEGARDWAISRNRYWGTPIPIWRSEDGELLVIRSIQELEE
LSGQKIVDLHRHFIDEIVIHKNGKSFHRIPYVFDCWFDSGAMPYAQNHYPFERAEETEARFPADFIAEGLDQTRGWFYTL
TVIAAALFDQPAFKNVIVNGIVLAEDGNKMSKRLNNYPSPKKIMDTYGADALRLYLLNSVVVKAEDLRFSDKGVEAVLKQ
VLLPLSNALAFYKTYAELYGFSPNETTDLELAEIDRWILSSLYSLVGKTRENMAQYDLHAAVSPFIDFIEDLTNWYIRRS
RRRFWESEDSPDRRAAFATLYEVLMVFSKIIAPFIPFTAEDMYQQLRVETDPESVHLCDFPHVVLEKILPDLEKKMQDIR
EIVALGHSLRKEHKLKVRQPLQHMYIVGAKERMAALAQVDSLIGEELNVKEVHFCSETPEYVTTLVKPNFRSLGKRVGNR
LPEIQKALAGLSQEQIQAFMHNGFMVLSLGEETISLNEEDITVSWEAAPGFVARSSASFVAILDCQLTSPLIMEGIAREI
VNKINTMRRNGKLHVSDRIAIRLHAPKIVQEAFSQYEEYICEETLTTSVSFIDDKEGEEWDVNGHAVSLSLEVIGH
>Mature_1036_residues
MDNEDKVSFPAKEEKVLTFWKEQNIFQKTLENRDGSPTFSFYDGPPFATGLPHYGHLLAGTIKDVVCRYATMDGHYVPRR
FGWDCHGVPVEYEVEKSLGLTEPGAIDRFGIANFNEECRKIVFRYVDEWKYFVDRIGRWVDFSATWKTMDLSFMESVWWV
FHSLYKQGLVYEGTKVVPFSTKLGTPLSNFEAGQNYKEVDDPSVVAKFALQDDQGILLAWTTTPWTLVSNMALAVHPGLT
YVRIQDKESGEEYILGQESLARWFPDRESYKWIGQLSGESLVGRRYCPLFPYFQDQQDRGAFRVIPADFIEESEGTGVVH
MAPAFGEADFFACQEHNVPLVCPVDNQGCFTSEVTDFVGEYIKFADKGIARRLKNENKLFYQGTIRHRYPFCWRTDSPLI
YKAVNSWFVSVEKVKHKMLKANESIHWTPGHIKHGRFGKWLEGARDWAISRNRYWGTPIPIWRSEDGELLVIRSIQELEE
LSGQKIVDLHRHFIDEIVIHKNGKSFHRIPYVFDCWFDSGAMPYAQNHYPFERAEETEARFPADFIAEGLDQTRGWFYTL
TVIAAALFDQPAFKNVIVNGIVLAEDGNKMSKRLNNYPSPKKIMDTYGADALRLYLLNSVVVKAEDLRFSDKGVEAVLKQ
VLLPLSNALAFYKTYAELYGFSPNETTDLELAEIDRWILSSLYSLVGKTRENMAQYDLHAAVSPFIDFIEDLTNWYIRRS
RRRFWESEDSPDRRAAFATLYEVLMVFSKIIAPFIPFTAEDMYQQLRVETDPESVHLCDFPHVVLEKILPDLEKKMQDIR
EIVALGHSLRKEHKLKVRQPLQHMYIVGAKERMAALAQVDSLIGEELNVKEVHFCSETPEYVTTLVKPNFRSLGKRVGNR
LPEIQKALAGLSQEQIQAFMHNGFMVLSLGEETISLNEEDITVSWEAAPGFVARSSASFVAILDCQLTSPLIMEGIAREI
VNKINTMRRNGKLHVSDRIAIRLHAPKIVQEAFSQYEEYICEETLTTSVSFIDDKEGEEWDVNGHAVSLSLEVIGH

Specific function: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activi

COG id: COG0060

COG function: function code J; Isoleucyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily

Homologues:

Organism=Homo sapiens, GI94721239, Length=1013, Percent_Identity=47.8775913129319, Blast_Score=947, Evalue=0.0,
Organism=Homo sapiens, GI94721241, Length=1013, Percent_Identity=47.8775913129319, Blast_Score=947, Evalue=0.0,
Organism=Homo sapiens, GI46852147, Length=785, Percent_Identity=29.0445859872611, Blast_Score=291, Evalue=3e-78,
Organism=Homo sapiens, GI5454158, Length=834, Percent_Identity=22.1822541966427, Blast_Score=149, Evalue=9e-36,
Organism=Homo sapiens, GI268370293, Length=880, Percent_Identity=24.2045454545455, Blast_Score=148, Evalue=3e-35,
Organism=Homo sapiens, GI268370297, Length=880, Percent_Identity=24.2045454545455, Blast_Score=147, Evalue=4e-35,
Organism=Homo sapiens, GI268370295, Length=861, Percent_Identity=24.0418118466899, Blast_Score=144, Evalue=5e-34,
Organism=Escherichia coli, GI2367096, Length=785, Percent_Identity=26.7515923566879, Blast_Score=298, Evalue=2e-81,
Organism=Escherichia coli, GI1790708, Length=894, Percent_Identity=22.1476510067114, Blast_Score=139, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI17541896, Length=1021, Percent_Identity=45.5435847208619, Blast_Score=893, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71980946, Length=888, Percent_Identity=25.2252252252252, Blast_Score=229, Evalue=4e-60,
Organism=Caenorhabditis elegans, GI17510661, Length=883, Percent_Identity=21.4043035107588, Blast_Score=150, Evalue=4e-36,
Organism=Caenorhabditis elegans, GI72001587, Length=849, Percent_Identity=21.9081272084806, Blast_Score=141, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6319395, Length=1065, Percent_Identity=42.9107981220657, Blast_Score=847, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6325217, Length=792, Percent_Identity=25, Blast_Score=229, Evalue=1e-60,
Organism=Saccharomyces cerevisiae, GI6321531, Length=781, Percent_Identity=22.663252240717, Blast_Score=154, Evalue=6e-38,
Organism=Drosophila melanogaster, GI28574730, Length=1012, Percent_Identity=43.4782608695652, Blast_Score=849, Evalue=0.0,
Organism=Drosophila melanogaster, GI24668547, Length=1012, Percent_Identity=43.4782608695652, Blast_Score=849, Evalue=0.0,
Organism=Drosophila melanogaster, GI24668543, Length=1012, Percent_Identity=43.4782608695652, Blast_Score=849, Evalue=0.0,
Organism=Drosophila melanogaster, GI281366294, Length=801, Percent_Identity=27.5905118601748, Blast_Score=260, Evalue=3e-69,
Organism=Drosophila melanogaster, GI17864482, Length=851, Percent_Identity=23.7367802585194, Blast_Score=163, Evalue=5e-40,
Organism=Drosophila melanogaster, GI24653289, Length=851, Percent_Identity=23.7367802585194, Blast_Score=163, Evalue=5e-40,
Organism=Drosophila melanogaster, GI21355675, Length=849, Percent_Identity=21.4369846878681, Blast_Score=152, Evalue=1e-36,

Paralogues:

None

Copy number: 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYI_CHLMU (Q9PL20)

Other databases:

- EMBL:   AE002160
- PIR:   F81719
- RefSeq:   NP_296667.1
- ProteinModelPortal:   Q9PL20
- SMR:   Q9PL20
- GeneID:   1246458
- GenomeReviews:   AE002160_GR
- KEGG:   cmu:TC0288
- TIGR:   TC_0288
- HOGENOM:   HBG577712
- OMA:   VEYEVEK
- PhylomeDB:   Q9PL20
- ProtClustDB:   PRK06039
- BioCyc:   CMUR243161:TC_0288-MONOMER
- BRENDA:   6.1.1.5
- GO:   GO:0005737
- HAMAP:   MF_02003
- InterPro:   IPR001412
- InterPro:   IPR002300
- InterPro:   IPR002301
- InterPro:   IPR014729
- InterPro:   IPR009080
- InterPro:   IPR013155
- InterPro:   IPR009008
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR11946:SF9
- PRINTS:   PR00984
- TIGRFAMs:   TIGR00392

Pfam domain/function: PF08264 Anticodon_1; PF00133 tRNA-synt_1; SSF47323 tRNAsyn_1a_bind; SSF50677 ValRS_IleRS_edit

EC number: =6.1.1.5

Molecular weight: Translated: 118951; Mature: 118951

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: BINDING 592-592

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNEDKVSFPAKEEKVLTFWKEQNIFQKTLENRDGSPTFSFYDGPPFATGLPHYGHLLAG
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCHHHHHHH
TIKDVVCRYATMDGHYVPRRFGWDCHGVPVEYEVEKSLGLTEPGAIDRFGIANFNEECRK
HHHHHHHHHHCCCCCCCCHHCCCCCCCCCCEEEEHHHCCCCCCCCCCCCCCCCCCHHHHH
IVFRYVDEWKYFVDRIGRWVDFSATWKTMDLSFMESVWWVFHSLYKQGLVYEGTKVVPFS
HHHHHHHHHHHHHHHHCCEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCEECCCEEEEEC
TKLGTPLSNFEAGQNYKEVDDPSVVAKFALQDDQGILLAWTTTPWTLVSNMALAVHPGLT
HHCCCCCHHCCCCCCCCCCCCHHHHHHHEEECCCCEEEEECCCCHHHHHCCEEEEECCEE
YVRIQDKESGEEYILGQESLARWFPDRESYKWIGQLSGESLVGRRYCPLFPYFQDQQDRG
EEEEECCCCCCCEECCHHHHHHHCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC
AFRVIPADFIEESEGTGVVHMAPAFGEADFFACQEHNVPLVCPVDNQGCFTSEVTDFVGE
CEEEECHHHHCCCCCCCEEEECCCCCCCCEEEECCCCCEEEEECCCCCCCHHHHHHHHHH
YIKFADKGIARRLKNENKLFYQGTIRHRYPFCWRTDSPLIYKAVNSWFVSVEKVKHKMLK
HHHHHHHHHHHHHCCCCEEEEEEEECCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHH
ANESIHWTPGHIKHGRFGKWLEGARDWAISRNRYWGTPIPIWRSEDGELLVIRSIQELEE
CCCCEEECCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCEECCCCCEEEEHHHHHHHH
LSGQKIVDLHRHFIDEIVIHKNGKSFHRIPYVFDCWFDSGAMPYAQNHYPFERAEETEAR
CCCCHHHHHHHHHHHHHEEECCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCHHHHC
FPADFIAEGLDQTRGWFYTLTVIAAALFDQPAFKNVIVNGIVLAEDGNKMSKRLNNYPSP
CCHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHCCEEEECCCCHHHHHHCCCCCH
KKIMDTYGADALRLYLLNSVVVKAEDLRFSDKGVEAVLKQVLLPLSNALAFYKTYAELYG
HHHHHHCCCHHHHHHHHHHHHEEHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
FSPNETTDLELAEIDRWILSSLYSLVGKTRENMAQYDLHAAVSPFIDFIEDLTNWYIRRS
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RRRFWESEDSPDRRAAFATLYEVLMVFSKIIAPFIPFTAEDMYQQLRVETDPESVHLCDF
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCEEECCC
PHVVLEKILPDLEKKMQDIREIVALGHSLRKEHKLKVRQPLQHMYIVGAKERMAALAQVD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCHHHHHHHHHHH
SLIGEELNVKEVHFCSETPEYVTTLVKPNFRSLGKRVGNRLPEIQKALAGLSQEQIQAFM
HHHCCCCCCCEEEECCCCHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHH
HNGFMVLSLGEETISLNEEDITVSWEAAPGFVARSSASFVAILDCQLTSPLIMEGIAREI
HCCEEEEEECCHHEECCCCCEEEEEECCCCCEEECCCCEEEEEEECCCCHHHHHHHHHHH
VNKINTMRRNGKLHVSDRIAIRLHAPKIVQEAFSQYEEYICEETLTTSVSFIDDKEGEEW
HHHHHHHHHCCEEEEECEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCEE
DVNGHAVSLSLEVIGH
CCCCEEEEEEEEEECC
>Mature Secondary Structure
MDNEDKVSFPAKEEKVLTFWKEQNIFQKTLENRDGSPTFSFYDGPPFATGLPHYGHLLAG
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCHHHHHHH
TIKDVVCRYATMDGHYVPRRFGWDCHGVPVEYEVEKSLGLTEPGAIDRFGIANFNEECRK
HHHHHHHHHHCCCCCCCCHHCCCCCCCCCCEEEEHHHCCCCCCCCCCCCCCCCCCHHHHH
IVFRYVDEWKYFVDRIGRWVDFSATWKTMDLSFMESVWWVFHSLYKQGLVYEGTKVVPFS
HHHHHHHHHHHHHHHHCCEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCEECCCEEEEEC
TKLGTPLSNFEAGQNYKEVDDPSVVAKFALQDDQGILLAWTTTPWTLVSNMALAVHPGLT
HHCCCCCHHCCCCCCCCCCCCHHHHHHHEEECCCCEEEEECCCCHHHHHCCEEEEECCEE
YVRIQDKESGEEYILGQESLARWFPDRESYKWIGQLSGESLVGRRYCPLFPYFQDQQDRG
EEEEECCCCCCCEECCHHHHHHHCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC
AFRVIPADFIEESEGTGVVHMAPAFGEADFFACQEHNVPLVCPVDNQGCFTSEVTDFVGE
CEEEECHHHHCCCCCCCEEEECCCCCCCCEEEECCCCCEEEEECCCCCCCHHHHHHHHHH
YIKFADKGIARRLKNENKLFYQGTIRHRYPFCWRTDSPLIYKAVNSWFVSVEKVKHKMLK
HHHHHHHHHHHHHCCCCEEEEEEEECCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHH
ANESIHWTPGHIKHGRFGKWLEGARDWAISRNRYWGTPIPIWRSEDGELLVIRSIQELEE
CCCCEEECCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCEECCCCCEEEEHHHHHHHH
LSGQKIVDLHRHFIDEIVIHKNGKSFHRIPYVFDCWFDSGAMPYAQNHYPFERAEETEAR
CCCCHHHHHHHHHHHHHEEECCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCHHHHC
FPADFIAEGLDQTRGWFYTLTVIAAALFDQPAFKNVIVNGIVLAEDGNKMSKRLNNYPSP
CCHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHCCEEEECCCCHHHHHHCCCCCH
KKIMDTYGADALRLYLLNSVVVKAEDLRFSDKGVEAVLKQVLLPLSNALAFYKTYAELYG
HHHHHHCCCHHHHHHHHHHHHEEHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
FSPNETTDLELAEIDRWILSSLYSLVGKTRENMAQYDLHAAVSPFIDFIEDLTNWYIRRS
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RRRFWESEDSPDRRAAFATLYEVLMVFSKIIAPFIPFTAEDMYQQLRVETDPESVHLCDF
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCEEECCC
PHVVLEKILPDLEKKMQDIREIVALGHSLRKEHKLKVRQPLQHMYIVGAKERMAALAQVD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCHHHHHHHHHHH
SLIGEELNVKEVHFCSETPEYVTTLVKPNFRSLGKRVGNRLPEIQKALAGLSQEQIQAFM
HHHCCCCCCCEEEECCCCHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHH
HNGFMVLSLGEETISLNEEDITVSWEAAPGFVARSSASFVAILDCQLTSPLIMEGIAREI
HCCEEEEEECCHHEECCCCCEEEEEECCCCCEEECCCCEEEEEEECCCCHHHHHHHHHHH
VNKINTMRRNGKLHVSDRIAIRLHAPKIVQEAFSQYEEYICEETLTTSVSFIDDKEGEEW
HHHHHHHHHCCEEEEECEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCEE
DVNGHAVSLSLEVIGH
CCCCEEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10684935