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Identifier: 15834852

GI number: 15834852

Start: 274553

End: 275026

Strand: Direct

Name: Not Available

Synonym: TC0232

Alternate gene names: 15834852

Gene position: 274553-275026 (Clockwise)

Preceding gene: 15834849

Following gene: 15834853

Centisome position: 25.59

GC content: 41.14

Gene sequence:

>474_bases
ATGTGTATAGAAAAAGATTTATTTTTCATGAAGAAGGCTCTAGATGAGGCTAGGAAGGCATATGAACTAGATGAGGTTCC
TGTCGGTTGCATCATTGTTCAAGGAGATGCGATCATAGCTAGAGGTCACAATAGTGTGGAGCGATTAAAAGACCCGACAG
CGCATGCTGAAATGATTTGTATTAGTGCGGCAGCAGAGTATCTCCAAAATTGGAGGCTAAAAGATACCACTCTGTATTGT
ACTTTAGAGCCCTGTCTAATGTGTGCGGGAGCAATTCAGTTAGCGCGTATTCCCAGAATTGTTTGGGGGGCTCCTGATTT
GCGATTGGGGGCTGGAGGTAGTTGGTTAAATGTTTTTTTGGAAAAACATCCTTTTCATCAAGTAGAGTGCTGCCCAGGGA
TTTGTCATCAAGAGTCTGAATGGTTGATGAAAAACTTTTTTTGGGAGAAAAGAAAGGAGAAAAATGAAAAATAA

Upstream 100 bases:

>100_bases
AGTGATTTGTAGTATGTTATGAGGGCTTTTTGGTTAAGATAAAGGCTTGCTAATTATTGAAAGAAGCAAAGCTTTTTTTT
ATTAGGTTATAGTTATTTTT

Downstream 100 bases:

>100_bases
AATTTTTGAGTTACTTAATCACCTATATTCTAAGCAGGAAAAACGGCTAATGACTCTGGGTACTAGCATGGTTCCCGAAT
TGACAACAGAAGATCTTTTA

Product: cytidine/deoxycytidylate deaminase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 157; Mature: 157

Protein sequence:

>157_residues
MCIEKDLFFMKKALDEARKAYELDEVPVGCIIVQGDAIIARGHNSVERLKDPTAHAEMICISAAAEYLQNWRLKDTTLYC
TLEPCLMCAGAIQLARIPRIVWGAPDLRLGAGGSWLNVFLEKHPFHQVECCPGICHQESEWLMKNFFWEKRKEKNEK

Sequences:

>Translated_157_residues
MCIEKDLFFMKKALDEARKAYELDEVPVGCIIVQGDAIIARGHNSVERLKDPTAHAEMICISAAAEYLQNWRLKDTTLYC
TLEPCLMCAGAIQLARIPRIVWGAPDLRLGAGGSWLNVFLEKHPFHQVECCPGICHQESEWLMKNFFWEKRKEKNEK
>Mature_157_residues
MCIEKDLFFMKKALDEARKAYELDEVPVGCIIVQGDAIIARGHNSVERLKDPTAHAEMICISAAAEYLQNWRLKDTTLYC
TLEPCLMCAGAIQLARIPRIVWGAPDLRLGAGGSWLNVFLEKHPFHQVECCPGICHQESEWLMKNFFWEKRKEKNEK

Specific function: Deaminates adenosine-34 to inosine in tRNA-Arg2 [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI124107608, Length=146, Percent_Identity=34.9315068493151, Blast_Score=100, Evalue=9e-22,
Organism=Escherichia coli, GI145693172, Length=146, Percent_Identity=42.4657534246575, Blast_Score=125, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI17541138, Length=171, Percent_Identity=35.0877192982456, Blast_Score=93, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI17554608, Length=120, Percent_Identity=37.5, Blast_Score=79, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17555996, Length=97, Percent_Identity=39.1752577319588, Blast_Score=65, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6322425, Length=161, Percent_Identity=31.6770186335404, Blast_Score=79, Evalue=3e-16,
Organism=Drosophila melanogaster, GI21355527, Length=145, Percent_Identity=36.551724137931, Blast_Score=97, Evalue=6e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: NA

Molecular weight: Translated: 17981; Mature: 17981

Theoretical pI: Translated: 6.65; Mature: 6.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.7 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
8.9 %Cys+Met (Translated Protein)
5.7 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
8.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCIEKDLFFMKKALDEARKAYELDEVPVGCIIVQGDAIIARGHNSVERLKDPTAHAEMIC
CCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCEEEECCCCHHHHHCCCCCHHHHHH
ISAAAEYLQNWRLKDTTLYCTLEPCLMCAGAIQLARIPRIVWGAPDLRLGAGGSWLNVFL
HHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHCCHHEECCCCCEECCCCHHHHHHH
EKHPFHQVECCPGICHQESEWLMKNFFWEKRKEKNEK
HCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MCIEKDLFFMKKALDEARKAYELDEVPVGCIIVQGDAIIARGHNSVERLKDPTAHAEMIC
CCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCEEEECCCCHHHHHCCCCCHHHHHH
ISAAAEYLQNWRLKDTTLYCTLEPCLMCAGAIQLARIPRIVWGAPDLRLGAGGSWLNVFL
HHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHCCHHEECCCCCEECCCCHHHHHHH
EKHPFHQVECCPGICHQESEWLMKNFFWEKRKEKNEK
HCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11296296 [H]