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The map label for this gene is infC

Identifier: 15834841

GI number: 15834841

Start: 261216

End: 261776

Strand: Direct

Name: infC

Synonym: TC0221

Alternate gene names: 15834841

Gene position: 261216-261776 (Clockwise)

Preceding gene: 15834837

Following gene: 15834842

Centisome position: 24.35

GC content: 40.82

Gene sequence:

>561_bases
GTGGCTTTAAACCTAAAAATAAATAGGCAGATACGAGCTCCCAGGGTGCGTGTAATAGGTTCTTCTGGAGAGCAGCTAGG
CATATTGAGTATAAAAGAGGCCCTAGATTTAGCCAGGGAAGCTGATTTAGACCTTGTTGAGGTTGCTTCAAACTCAGAGC
CTCCCGTATGTAAGATCATGGACTACGGGAAGTATCGTTATGACGTAACTAAAAAAGAAAAGGATAGTAAGAAGGCTCAG
CACCAAGTGCGTGTCAAAGAGGTTAAGTTAAAGCCTAATATTGATGACAATGACTTTCTTACGAAAGTAAAGCAAGCTAG
AGCCTTTATTGAAAAAGGAAATAAAGTAAAAGTTTCTTGTATGTTTCGGGGGCGAGAGTTGGCTTATCCCGAACACGGGC
ATAAAGTTGTTCAAAGGATGTGCCAGGGCTTGGAAGATGTTGGTTTTGTTGAGTCTGAACCTAAACTAAATGGCCGTTCT
TTGATCTGTGTTATTGCTCCGGGAACACTAAAAACTAAGAAAAAACAGGAAAAAGTCCATGCCCAAGATGAAAAGCAATA
A

Upstream 100 bases:

>100_bases
GAAATTTGGTTTAGACCAAAAGGGAAGCCCTTCTTCTTGGAGAAGAGGGCTATAGTTTTGGGACTCTCCGCCGGCGATTA
CTAATTTTAGCAGGGTAGAT

Downstream 100 bases:

>100_bases
GTCCGTTGCGGCGCGTTTCAAATTGACTGGTTCTGGTCAATTAAAAAGAACTCGTCCGGGGAAAAGACACAAATTATCAA
AAAGATCTTCGCAACAGAAA

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 186; Mature: 185

Protein sequence:

>186_residues
MALNLKINRQIRAPRVRVIGSSGEQLGILSIKEALDLAREADLDLVEVASNSEPPVCKIMDYGKYRYDVTKKEKDSKKAQ
HQVRVKEVKLKPNIDDNDFLTKVKQARAFIEKGNKVKVSCMFRGRELAYPEHGHKVVQRMCQGLEDVGFVESEPKLNGRS
LICVIAPGTLKTKKKQEKVHAQDEKQ

Sequences:

>Translated_186_residues
MALNLKINRQIRAPRVRVIGSSGEQLGILSIKEALDLAREADLDLVEVASNSEPPVCKIMDYGKYRYDVTKKEKDSKKAQ
HQVRVKEVKLKPNIDDNDFLTKVKQARAFIEKGNKVKVSCMFRGRELAYPEHGHKVVQRMCQGLEDVGFVESEPKLNGRS
LICVIAPGTLKTKKKQEKVHAQDEKQ
>Mature_185_residues
ALNLKINRQIRAPRVRVIGSSGEQLGILSIKEALDLAREADLDLVEVASNSEPPVCKIMDYGKYRYDVTKKEKDSKKAQH
QVRVKEVKLKPNIDDNDFLTKVKQARAFIEKGNKVKVSCMFRGRELAYPEHGHKVVQRMCQGLEDVGFVESEPKLNGRSL
ICVIAPGTLKTKKKQEKVHAQDEKQ

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family

Homologues:

Organism=Escherichia coli, GI1788012, Length=172, Percent_Identity=47.093023255814, Blast_Score=150, Evalue=4e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): IF3_CHLMU (Q9PL86)

Other databases:

- EMBL:   AE002160
- PIR:   C81727
- RefSeq:   NP_296600.1
- ProteinModelPortal:   Q9PL86
- SMR:   Q9PL86
- GeneID:   1246348
- GenomeReviews:   AE002160_GR
- KEGG:   cmu:TC0221
- TIGR:   TC_0221
- HOGENOM:   HBG744268
- OMA:   FDRRAPV
- PhylomeDB:   Q9PL86
- ProtClustDB:   PRK00028
- BioCyc:   CMUR243161:TC_0221-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00080
- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814
- Gene3D:   G3DSA:3.10.20.80
- Gene3D:   G3DSA:3.30.110.10
- PANTHER:   PTHR10938
- TIGRFAMs:   TIGR00168

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N; SSF54364 IF3; SSF55200 IF3

EC number: NA

Molecular weight: Translated: 21069; Mature: 20938

Theoretical pI: Translated: 10.09; Mature: 10.09

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALNLKINRQIRAPRVRVIGSSGEQLGILSIKEALDLAREADLDLVEVASNSEPPVCKIM
CEEEEEECCCCCCCEEEEECCCCCEEEHHHHHHHHHHHHHCCCCEEEECCCCCCCEEEEE
DYGKYRYDVTKKEKDSKKAQHQVRVKEVKLKPNIDDNDFLTKVKQARAFIEKGNKVKVSC
ECCCEEEECCCCHHHHHHHHHHEEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCEEEEEE
MFRGRELAYPEHGHKVVQRMCQGLEDVGFVESEPKLNGRSLICVIAPGTLKTKKKQEKVH
EECCCCCCCCCCHHHHHHHHHHCHHHCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHC
AQDEKQ
CCCCCC
>Mature Secondary Structure 
ALNLKINRQIRAPRVRVIGSSGEQLGILSIKEALDLAREADLDLVEVASNSEPPVCKIM
EEEEEECCCCCCCEEEEECCCCCEEEHHHHHHHHHHHHHCCCCEEEECCCCCCCEEEEE
DYGKYRYDVTKKEKDSKKAQHQVRVKEVKLKPNIDDNDFLTKVKQARAFIEKGNKVKVSC
ECCCEEEECCCCHHHHHHHHHHEEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCEEEEEE
MFRGRELAYPEHGHKVVQRMCQGLEDVGFVESEPKLNGRSLICVIAPGTLKTKKKQEKVH
EECCCCCCCCCCHHHHHHHHHHCHHHCCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHC
AQDEKQ
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10684935