Click here to switch to the map view.

The map label for this gene is Not Available

Identifier: 15834825

GI number: 15834825

Start: 240982

End: 242169

Strand: Direct

Name: Not Available

Synonym: TC0205

Alternate gene names: 15834825

Gene position: 240982-242169 (Clockwise)

Preceding gene: 15834824

Following gene: 15834826

Centisome position: 22.46

GC content: 40.57

Gene sequence:

>1188_bases
ATGCGGAATAAATGTATAGGAGGGGTTTTAATTGTTGCTGGAACCGTGATCGGAGCCGGAGTATTAGCTGTGCCTGTTTT
AACAGCTTTGGATGGGTTTTTGCCTGCTGCCTTACTGTATATGCTTGCTTGGTTAGTGTCATTGGCCTCTGGTTATGGTT
ATTTGGAGGTTTTGACCTGGTGCAAAGGGAATAAGCAAGCGAATTTGTGCTCCATGGCAGAAGAAACTTTGGGGAAAGTA
GGACGCATAGTTTTGTGTTTAGTCTACTTGTTTTTATTTTATTCCTTACTTGTTGCCTACTTTTGCGATGGGGGGAATAT
TCTTTCTCGTATGCTTGGAGATGGGGTTCTTGAAAATCCATGGGCTCGGCATGTTATGCCTATCTTATTTTTCTGCATTT
TTGCTCCTTTACTTATGGCAAAAACCTCGATCATCGATTACTGCAACCGAGTATTTGTTTTCGGTCTTATCCTGGTTTTC
GGTCTTTTCTGTATCTTGGGAGCTCCGCGTGTGCAAGGGGATCTTTTATTAAGAGCATCATGGTTTTCTTCCCTAAATAG
TTTGCCTATTTTTTTCTTGGCTTTTGGTTTTCAAAATGTCGTGCCTTCATTGTACCATTACTTAGATGGGGATGTTCGAG
AAGTTAAACGGGCAATTTTTATAGGAAGCCTGATTCCTTTAGTTTTGTATGTAATTTGGGAAGCATTGGTTCTTGGTACA
GTTCCATTAGTTTATTTGCTGAAAGCTAAGGAACTAGGATGGACTGCTGCAGGTGCTCTTCAAGGAGCTTTAAAAAATTC
TGCTTTTCATATCGCTGGAGAATTATTCGGATTCTTTGCGCTAGTCACCTCTTTTATAGGGACTGCATTGGCCTTGAAAG
ATTTTTATATAGATATTTTTAAATGGGATGCTCGTAAGCAGCGATTGAATTTATTTTTATTAGTTTTGGTGTTCCCATTG
GTATGGGCGGTTTCTTATCCCGAGATTGTTTTGTCTTGTTTGCGTTATGCTGGGGGAATAGGGGGAGCTTGTATTATCGT
ATTGTTCCCGGTAGCGATGCTATGGAATGGCCGGTATGGAAAACGGCATTGTTCTGGCAAACAAATATTGCCAGGAGGAA
AGACCGTCCTATTGATTTTATTAGGATATACTGTGCTAAATCTCGCACCCCTGTATTATACGTTTTAG

Upstream 100 bases:

>100_bases
TCTAGTCAGTACTCCCCCGTATAGGACTGGGGAGTTATTTTTTTAATAAGAAGAGATCTCCCTAGTGAAATAAGTACAAA
AGGGGAGAAGGAGGATATGT

Downstream 100 bases:

>100_bases
AAAGAAGAAGTGTAAAAAGTTTTTAAATAGGAGATCTCCATGGGATTATACGATCGTGATTACACGCAGGATTCCCGTTT
ACCAGGGACCTTCTCTTCCA

Product: Mtr/TnaB/TyrO permease family protein

Products: Proton [Cytoplasm]; L-tyrosine [Cytoplasm] [C]

Alternate protein names: Tyrosine permease 1 [H]

Number of amino acids: Translated: 395; Mature: 395

Protein sequence:

>395_residues
MRNKCIGGVLIVAGTVIGAGVLAVPVLTALDGFLPAALLYMLAWLVSLASGYGYLEVLTWCKGNKQANLCSMAEETLGKV
GRIVLCLVYLFLFYSLLVAYFCDGGNILSRMLGDGVLENPWARHVMPILFFCIFAPLLMAKTSIIDYCNRVFVFGLILVF
GLFCILGAPRVQGDLLLRASWFSSLNSLPIFFLAFGFQNVVPSLYHYLDGDVREVKRAIFIGSLIPLVLYVIWEALVLGT
VPLVYLLKAKELGWTAAGALQGALKNSAFHIAGELFGFFALVTSFIGTALALKDFYIDIFKWDARKQRLNLFLLVLVFPL
VWAVSYPEIVLSCLRYAGGIGGACIIVLFPVAMLWNGRYGKRHCSGKQILPGGKTVLLILLGYTVLNLAPLYYTF

Sequences:

>Translated_395_residues
MRNKCIGGVLIVAGTVIGAGVLAVPVLTALDGFLPAALLYMLAWLVSLASGYGYLEVLTWCKGNKQANLCSMAEETLGKV
GRIVLCLVYLFLFYSLLVAYFCDGGNILSRMLGDGVLENPWARHVMPILFFCIFAPLLMAKTSIIDYCNRVFVFGLILVF
GLFCILGAPRVQGDLLLRASWFSSLNSLPIFFLAFGFQNVVPSLYHYLDGDVREVKRAIFIGSLIPLVLYVIWEALVLGT
VPLVYLLKAKELGWTAAGALQGALKNSAFHIAGELFGFFALVTSFIGTALALKDFYIDIFKWDARKQRLNLFLLVLVFPL
VWAVSYPEIVLSCLRYAGGIGGACIIVLFPVAMLWNGRYGKRHCSGKQILPGGKTVLLILLGYTVLNLAPLYYTF
>Mature_395_residues
MRNKCIGGVLIVAGTVIGAGVLAVPVLTALDGFLPAALLYMLAWLVSLASGYGYLEVLTWCKGNKQANLCSMAEETLGKV
GRIVLCLVYLFLFYSLLVAYFCDGGNILSRMLGDGVLENPWARHVMPILFFCIFAPLLMAKTSIIDYCNRVFVFGLILVF
GLFCILGAPRVQGDLLLRASWFSSLNSLPIFFLAFGFQNVVPSLYHYLDGDVREVKRAIFIGSLIPLVLYVIWEALVLGT
VPLVYLLKAKELGWTAAGALQGALKNSAFHIAGELFGFFALVTSFIGTALALKDFYIDIFKWDARKQRLNLFLLVLVFPL
VWAVSYPEIVLSCLRYAGGIGGACIIVLFPVAMLWNGRYGKRHCSGKQILPGGKTVLLILLGYTVLNLAPLYYTF

Specific function: Involved in transporting tyrosine across the cytoplasmic membrane [H]

COG id: COG0814

COG function: function code E; Amino acid permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid/polyamine transporter 2 family. Mtr/TnaB/TyrP permease subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788218, Length=391, Percent_Identity=29.156010230179, Blast_Score=142, Evalue=4e-35,
Organism=Escherichia coli, GI1789552, Length=368, Percent_Identity=27.1739130434783, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1790145, Length=408, Percent_Identity=24.7549019607843, Blast_Score=78, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002091
- InterPro:   IPR013061
- InterPro:   IPR013059
- InterPro:   IPR018227 [H]

Pfam domain/function: PF03222 Trp_Tyr_perm [H]

EC number: NA

Molecular weight: Translated: 43422; Mature: 43422

Theoretical pI: Translated: 8.93; Mature: 8.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure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CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; L-tyrosine [Periplasm] [C]

Specific reaction: Proton [Periplasm] + L-tyrosine [Periplasm] = Proton [Cytoplasm] + L-tyrosine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]