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The map label for this gene is pgsA

Identifier: 15834800

GI number: 15834800

Start: 214160

End: 214768

Strand: Direct

Name: pgsA

Synonym: TC0180

Alternate gene names: 15834800

Gene position: 214160-214768 (Clockwise)

Preceding gene: 15834799

Following gene: 15834802

Centisome position: 19.96

GC content: 39.08

Gene sequence:

>609_bases
ATGAGCGTGAGTTTACCGAACTACCTGACATTTTTTCGTCTATTCATCACACCAATTTTTATGATTTTGTATTTGAAGGG
AAAATGGTTTGGGTTATCTGCTACAGTTTTGCCGTATGTTTTACTATTTTTGCTTATCATAGCTGAGATTACAGATGCTG
TGGATGGGTATATTGCGAGAAAATTCTCTCAAGTCACAGACCTAGGGAAGCTTCTAGATCCTATGGCAGATAGTGTATAC
CGCATTTCATTGTATCTAACGTTTACGCAACCCCCAGTAAATCTCCCTCTCATACTTGTTTTCATTTTTTTAGCTAGAGA
TTCTGTGACGAGTACATTGCGTATGTTATGTGCTAGTAGGGGGCAGGTGTTAGCTGCTAGGACAAGCGGGAAGTTAAAGG
CAATTCTTCAAGCTATCAGTTTCTTTTTAATTATTTTTGCTATGTTCTTTTGCGCAAAAGGAATCATCTCCACGGATGAT
TTGGAGTTTTTTGCCACGATCACAGTTTCTTTGGTAGCTTTTTACTCTGTCTGCTCTGGAGTTGAGTATATTTGGGTAAA
TAAGAGCCATTTATTGCAGAAGAATGACTCGCCAGATGGCGAGTCATAG

Upstream 100 bases:

>100_bases
AGGGATGGTACGAAAGAGTCTGATTAGTATGTGCGTGGCGCTGACTTTTTCAAACGGGCGCGAAACTTGGGTATTCAAAG
AAAGATTTCCAGGGGAACAG

Downstream 100 bases:

>100_bases
GGGATTTATTGTTGATAAATTTCTAAATATTTATTGGCTGCAGTTTCTAAGTCCGAAGAAAACTCTAAGCAAGAGCGAAC
AATCTGTTGCCACTTATCTT

Product: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 202; Mature: 201

Protein sequence:

>202_residues
MSVSLPNYLTFFRLFITPIFMILYLKGKWFGLSATVLPYVLLFLLIIAEITDAVDGYIARKFSQVTDLGKLLDPMADSVY
RISLYLTFTQPPVNLPLILVFIFLARDSVTSTLRMLCASRGQVLAARTSGKLKAILQAISFFLIIFAMFFCAKGIISTDD
LEFFATITVSLVAFYSVCSGVEYIWVNKSHLLQKNDSPDGES

Sequences:

>Translated_202_residues
MSVSLPNYLTFFRLFITPIFMILYLKGKWFGLSATVLPYVLLFLLIIAEITDAVDGYIARKFSQVTDLGKLLDPMADSVY
RISLYLTFTQPPVNLPLILVFIFLARDSVTSTLRMLCASRGQVLAARTSGKLKAILQAISFFLIIFAMFFCAKGIISTDD
LEFFATITVSLVAFYSVCSGVEYIWVNKSHLLQKNDSPDGES
>Mature_201_residues
SVSLPNYLTFFRLFITPIFMILYLKGKWFGLSATVLPYVLLFLLIIAEITDAVDGYIARKFSQVTDLGKLLDPMADSVYR
ISLYLTFTQPPVNLPLILVFIFLARDSVTSTLRMLCASRGQVLAARTSGKLKAILQAISFFLIIFAMFFCAKGIISTDDL
EFFATITVSLVAFYSVCSGVEYIWVNKSHLLQKNDSPDGES

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids [H]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1788220, Length=146, Percent_Identity=30.8219178082192, Blast_Score=63, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 22616; Mature: 22485

Theoretical pI: Translated: 8.44; Mature: 8.44

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVSLPNYLTFFRLFITPIFMILYLKGKWFGLSATVLPYVLLFLLIIAEITDAVDGYIAR
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KFSQVTDLGKLLDPMADSVYRISLYLTFTQPPVNLPLILVFIFLARDSVTSTLRMLCASR
HHHHHHHHHHHHHHHHHCEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
GQVLAARTSGKLKAILQAISFFLIIFAMFFCAKGIISTDDLEFFATITVSLVAFYSVCSG
CCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCC
VEYIWVNKSHLLQKNDSPDGES
CEEEEECHHHHHCCCCCCCCCC
>Mature Secondary Structure 
SVSLPNYLTFFRLFITPIFMILYLKGKWFGLSATVLPYVLLFLLIIAEITDAVDGYIAR
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KFSQVTDLGKLLDPMADSVYRISLYLTFTQPPVNLPLILVFIFLARDSVTSTLRMLCASR
HHHHHHHHHHHHHHHHHCEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
GQVLAARTSGKLKAILQAISFFLIIFAMFFCAKGIISTDDLEFFATITVSLVAFYSVCSG
CCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCC
VEYIWVNKSHLLQKNDSPDGES
CEEEEECHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7750561; 9384377 [H]