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The map label for this gene is murG

Identifier: 15834762

GI number: 15834762

Start: 173450

End: 174511

Strand: Direct

Name: murG

Synonym: TC0142

Alternate gene names: 15834762

Gene position: 173450-174511 (Clockwise)

Preceding gene: 15834761

Following gene: 15834763

Centisome position: 16.17

GC content: 40.96

Gene sequence:

>1062_bases
GTGATGAAGAAGATCAGCAAGGTTGTATTGGCAGTAGGGGGAACAGGGGGACACATTATCCCCGCTTTAGCAGCCAGAGA
GACTTTCATTAAGGAGAAAGTAGAAGTTCTACTTTTAGGAAAGGGGTTAACGCGTTTCTTGGAAGGAGAACCAGATGTAT
TGTACTACGATATTCCTTCTGGATCTCCCTTTTCTCTTCGTCCAAATCAAATGTTTTCTGGAGCACGGCAGTTGTATCAA
GGATATACGGCTGCGCTTCGGATGATAAAATCTTTCGCTCCAGATGTAGCAGTAGGATTTGGGAGCTATCATTCCCTTCC
TGCTATTCTCGCTTCTATCAGAAAGAGAATTCCTCTATTTCTTCATGAACAAAATGTTGTTCCAGGGAAAGTCAACAAGC
TGTTTTCTCATTTTGCTAAAGGGGTAGGGATGTCTTTTTCGGCAGCTGGAGAGCATTTTCGTTGTCGAGCAGAAGAGGTA
TTTCTTCCTATCAGAGAGCCATCAGAGCAGATCGTTTTTCCAGAAGCTTCTCCTGTAATTTGTGTAGTAGGAGGATCTCA
GGGAGCAAAAATTTTAAACGATTGTGTCCCTAAAGCTTTGGCTTATGTTCGTGAAAAACATGCGAATTTATATGTTCATC
ATATTGTAGGCCCTAAAGGAGACCTGGAAGGGGTTTCTCGAGTTTATCAAGATGCTGGAATTCAGCATAAAGTAACGTTT
TTTGAAAAAAATATACTTGGAGTATTGCAAGCGAGTGATTTAGTAATTGGAAGGGCAGGTGCTACGATTCTTAATGAGTT
GCTTTGGGTTCAGGTGCCAGCTATTTTGATTCCTTATCCAGGAGCTCATGGACATCAAGAAGCAAATGCAAAATTTTTCA
CACAAACTCTTGGTGGTGGGACCATGATTTTGCAAAAGCATTTGACAGAAGAAAGTTTACGTAAGCAGGTTTTGCTTGCT
TTAGATCCAGCAACTAGTGAAAATAGGCGCAAAGCTATGCTGGATGCTCAAAAGAACAAATCCTTCAAATCATTATATCA
GTTTATCTGCGAATCTCTATAG

Upstream 100 bases:

>100_bases
GGGTTATTGCCTAGTAAGGGAGTGAATCTTCCTTTTTTTAGTCAGGGAGGATCTTCTCTAATTGCTAATATGTGTGGCAT
TGGATTGCTATTAAGGATAT

Downstream 100 bases:

>100_bases
GCTAACGATGAAAAGCTTGTGTTACCACTTCATTGGTATTGGTGGGATCGGAATGAGTGCTTTAGCTCATATTCTGCTTG
ACCGAGGATATAGCGTATCA

Product: undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase

Number of amino acids: Translated: 353; Mature: 353

Protein sequence:

>353_residues
MMKKISKVVLAVGGTGGHIIPALAARETFIKEKVEVLLLGKGLTRFLEGEPDVLYYDIPSGSPFSLRPNQMFSGARQLYQ
GYTAALRMIKSFAPDVAVGFGSYHSLPAILASIRKRIPLFLHEQNVVPGKVNKLFSHFAKGVGMSFSAAGEHFRCRAEEV
FLPIREPSEQIVFPEASPVICVVGGSQGAKILNDCVPKALAYVREKHANLYVHHIVGPKGDLEGVSRVYQDAGIQHKVTF
FEKNILGVLQASDLVIGRAGATILNELLWVQVPAILIPYPGAHGHQEANAKFFTQTLGGGTMILQKHLTEESLRKQVLLA
LDPATSENRRKAMLDAQKNKSFKSLYQFICESL

Sequences:

>Translated_353_residues
MMKKISKVVLAVGGTGGHIIPALAARETFIKEKVEVLLLGKGLTRFLEGEPDVLYYDIPSGSPFSLRPNQMFSGARQLYQ
GYTAALRMIKSFAPDVAVGFGSYHSLPAILASIRKRIPLFLHEQNVVPGKVNKLFSHFAKGVGMSFSAAGEHFRCRAEEV
FLPIREPSEQIVFPEASPVICVVGGSQGAKILNDCVPKALAYVREKHANLYVHHIVGPKGDLEGVSRVYQDAGIQHKVTF
FEKNILGVLQASDLVIGRAGATILNELLWVQVPAILIPYPGAHGHQEANAKFFTQTLGGGTMILQKHLTEESLRKQVLLA
LDPATSENRRKAMLDAQKNKSFKSLYQFICESL
>Mature_353_residues
MMKKISKVVLAVGGTGGHIIPALAARETFIKEKVEVLLLGKGLTRFLEGEPDVLYYDIPSGSPFSLRPNQMFSGARQLYQ
GYTAALRMIKSFAPDVAVGFGSYHSLPAILASIRKRIPLFLHEQNVVPGKVNKLFSHFAKGVGMSFSAAGEHFRCRAEEV
FLPIREPSEQIVFPEASPVICVVGGSQGAKILNDCVPKALAYVREKHANLYVHHIVGPKGDLEGVSRVYQDAGIQHKVTF
FEKNILGVLQASDLVIGRAGATILNELLWVQVPAILIPYPGAHGHQEANAKFFTQTLGGGTMILQKHLTEESLRKQVLLA
LDPATSENRRKAMLDAQKNKSFKSLYQFICESL

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily

Homologues:

Organism=Escherichia coli, GI1786278, Length=325, Percent_Identity=28, Blast_Score=116, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURG_CHLMU (Q9PLG2)

Other databases:

- EMBL:   AE002160
- PIR:   A81737
- RefSeq:   NP_296521.1
- ProteinModelPortal:   Q9PLG2
- SMR:   Q9PLG2
- GeneID:   1245676
- GenomeReviews:   AE002160_GR
- KEGG:   cmu:TC0142
- TIGR:   TC_0142
- HOGENOM:   HBG617076
- OMA:   PHGNGEQ
- ProtClustDB:   PRK00726
- BioCyc:   CMUR243161:TC_0142-MONOMER
- BRENDA:   2.4.1.227
- HAMAP:   MF_00033
- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235
- TIGRFAMs:   TIGR01133

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28

EC number: =2.4.1.227

Molecular weight: Translated: 38704; Mature: 38704

Theoretical pI: Translated: 9.77; Mature: 9.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMKKISKVVLAVGGTGGHIIPALAARETFIKEKVEVLLLGKGLTRFLEGEPDVLYYDIPS
CCHHHEEEEEEECCCCCCHHHHHHHHHHHHHHHHHEEEECCHHHHHHCCCCCEEEEECCC
GSPFSLRPNQMFSGARQLYQGYTAALRMIKSFAPDVAVGFGSYHSLPAILASIRKRIPLF
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCHHHHHHHHHHHHHHCCEE
LHEQNVVPGKVNKLFSHFAKGVGMSFSAAGEHFRCRAEEVFLPIREPSEQIVFPEASPVI
EECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCEECHHHEEEECCCCCCCEECCCCCCEE
CVVGGSQGAKILNDCVPKALAYVREKHANLYVHHIVGPKGDLEGVSRVYQDAGIQHKVTF
EEEECCCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHCCCCEEEHH
FEKNILGVLQASDLVIGRAGATILNELLWVQVPAILIPYPGAHGHQEANAKFFTQTLGGG
HHHHHHHHHHHCCEEEECCCHHHHHHHHHHHCCEEEEECCCCCCCCCCCCHHHHHHCCCC
TMILQKHLTEESLRKQVLLALDPATSENRRKAMLDAQKNKSFKSLYQFICESL
HHHHHHHHHHHHHHHHEEEEECCCCCCCHHHHHHHHHCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MMKKISKVVLAVGGTGGHIIPALAARETFIKEKVEVLLLGKGLTRFLEGEPDVLYYDIPS
CCHHHEEEEEEECCCCCCHHHHHHHHHHHHHHHHHEEEECCHHHHHHCCCCCEEEEECCC
GSPFSLRPNQMFSGARQLYQGYTAALRMIKSFAPDVAVGFGSYHSLPAILASIRKRIPLF
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCHHHHHHHHHHHHHHCCEE
LHEQNVVPGKVNKLFSHFAKGVGMSFSAAGEHFRCRAEEVFLPIREPSEQIVFPEASPVI
EECCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCEECHHHEEEECCCCCCCEECCCCCCEE
CVVGGSQGAKILNDCVPKALAYVREKHANLYVHHIVGPKGDLEGVSRVYQDAGIQHKVTF
EEEECCCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHCCCCEEEHH
FEKNILGVLQASDLVIGRAGATILNELLWVQVPAILIPYPGAHGHQEANAKFFTQTLGGG
HHHHHHHHHHHCCEEEECCCHHHHHHHHHHHCCEEEEECCCCCCCCCCCCHHHHHHCCCC
TMILQKHLTEESLRKQVLLALDPATSENRRKAMLDAQKNKSFKSLYQFICESL
HHHHHHHHHHHHHHHHEEEEECCCCCCCHHHHHHHHHCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10684935