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The map label for this gene is tkt

Identifier: 15834751

GI number: 15834751

Start: 161045

End: 163045

Strand: Direct

Name: tkt

Synonym: TC0131

Alternate gene names: 15834751

Gene position: 161045-163045 (Clockwise)

Preceding gene: 15834744

Following gene: 15834753

Centisome position: 15.01

GC content: 41.83

Gene sequence:

>2001_bases
ATGGCTGGCAATAGTGAATTGGATATAGATATCTTGGAAAAGATTGCAGGGACTATTAAACAGTTGAGTATAGAGAGTAT
TCAAAAGGCTTCTTCAGGCCACCCAGGAATGCCATTAGGATGCGCTGAGATCGCAGCATATTTGTATGGTTGCGTATTGC
GATATAATTCTAAGGATTCTCAATGGATGAATAGAGATCGATTTGTTCTATCTGCAGGGCATGGTTCTGCTCTTCTTTAT
TCTTGTCTACATTTAGCAGGCTTTAATGTGAGGTTAGAGGATCTTCAGCAGTTTCGACAACTTCACTCCCAAACTCCTGG
GCATCCAGAATTTCGGGAAACGGATGGTGTTGAAGCGACAACTGGACCTTTAGGGCAAGGAATAGGGAATGCTGTAGGAA
TGGCTCTTTCATTGAAGATGTTGGGATCTAGATTCAATCAGTCTTCCACGTCCATTTTTGATGCTAAGGTCTATTGCTTG
GCAGGAGATGGATGCTTCATGGAAGGAGTAAGTCATGAAGCTTGTAGCTTTGCAGGTTCCTTGGGATTGGATAATCTTAT
TTTAATCTATGATTATAATGAGATTATTTTAGATGGGACTCTTCAAGATGTTAGTGTTGAGGATACGAAACAACGATTCT
TAGCCTATGGCTGGGATGTTTTTGAAGCCAATGGTCATGATTTTGAGGATTTACATCGGGTATTTTCTCAAATCAAAAAA
GGGCAACAAAAACCTACTTTGATTATTGCACATACTATTATTGGTCATGGATCTCCTAAAGAAGGAACGAACAAAGCTCA
TGGATCCCCTTTGGGAGAAGATGGAGTCGCGCAAACTAAAAGTTTTTGGCACCTGCCAGAAGAAAAGTTTTTTGTCCCTT
CATCTGTGAAGATGTTCTTTGCAGCAAAACAACAAGAAGGACAAAAATTACAGGAAGAATGGCAGGAGCGCTTCCGGGTG
TGGTCAAAACGATTCCCAGAACAACACCAGGAATATCTTAAGTTAACTCAAGAAATTTCCATTCAAGATCTTGAAGTATT
ATTGAATCTTATTGATATGCCAGAGTCTATAGCTGGACGGGCTGCTTCAAACAAAGTAATCCAGGTTTTGGCAGAGAATA
TTCCATCTCTAATAGGGGGATCGGCGGATCTTTCCAGCTCAGATGGTACCTGGATAGCTAAGGAGACTGCTGTCAACGCT
TCTCATTTTCAAGGTCGGAATATTCGCTATGGTGTACGAGAATTCGGCATGGGCACGATTATGAACGGACTCGCGTACAG
CCAGGTATTTCGTCCTTTTGGTGGAACATTTTTAGTATTTTCAGATTATTTACGTGCAGCGATTCGACTAGCAGCATTGT
CTAAGCTTCCGGTTATTTATCAATTTACACATGATTCTATTTTTGTTGGGGAAGATGGCCCTACTCATCAACCTATAGAG
CAAATTATGTCATTACGTGCAATACCAGGATTAAGGGTAGTGCGTCCTGCGGATGCGCATGAAGTAAAAGGAGCCTGGTT
ATCTGCATTAGAAAACTCAGGGCCTACAGCTTTGATTCTATCTAGACAAAATCTCCCAACTCTTAAAGAGACTAAACGGT
CGTTTAGAGATGGAGTAGGAAGAGGAGCTTATATTTTAGTTAAAGAAGAAGGGGGAAGCCCGGACTATACATTATGCGCT
TCTGGGTCAGAGGTACATTTGGCAATGGAAGTTGCGCAAAGCCTCATGGCTTTGGATAAGCGAGTTCGCGTAATTTCATT
CCCTTGTTGGGAGTTATTTGAGCGACAAGACCCCGAGTATCGTGAATCTGTGATTGGTGGGGACTTAGGATTGCGTGTCT
CTATAGAGGCCGGATCTGCTTTGGGGTGGTACAAATATATAGGCAGTAATGGCTTGTCTATTGCTATGGATGTGTTTGGT
ATGTCTGGAGCTCCCCACGAAGTTGCTGAAACTTGTGGTTTTACTGTGGATAGTATTGTTCAGAGAATTCTTTCTGTTTA
A

Upstream 100 bases:

>100_bases
ACTTTTGTATAATTATTTTGTTCCCCTTATTATCGCGCTTTCGATTTTACGTCGAAGCCGAATAATTCAATAGTGATCAA
CTTCTTCTAAAGGAAAAGAC

Downstream 100 bases:

>100_bases
AAGTCTCCGTCAGAAATTCCAGTTTGCTCAGACAGAGAATCATCGGCTTGCCCAAACTCCATATGTGGCAAGCCTTTTGT
TTTCTTAATGCCAGGCCCGA

Product: transketolase

Products: NA

Alternate protein names: TK [H]

Number of amino acids: Translated: 666; Mature: 665

Protein sequence:

>666_residues
MAGNSELDIDILEKIAGTIKQLSIESIQKASSGHPGMPLGCAEIAAYLYGCVLRYNSKDSQWMNRDRFVLSAGHGSALLY
SCLHLAGFNVRLEDLQQFRQLHSQTPGHPEFRETDGVEATTGPLGQGIGNAVGMALSLKMLGSRFNQSSTSIFDAKVYCL
AGDGCFMEGVSHEACSFAGSLGLDNLILIYDYNEIILDGTLQDVSVEDTKQRFLAYGWDVFEANGHDFEDLHRVFSQIKK
GQQKPTLIIAHTIIGHGSPKEGTNKAHGSPLGEDGVAQTKSFWHLPEEKFFVPSSVKMFFAAKQQEGQKLQEEWQERFRV
WSKRFPEQHQEYLKLTQEISIQDLEVLLNLIDMPESIAGRAASNKVIQVLAENIPSLIGGSADLSSSDGTWIAKETAVNA
SHFQGRNIRYGVREFGMGTIMNGLAYSQVFRPFGGTFLVFSDYLRAAIRLAALSKLPVIYQFTHDSIFVGEDGPTHQPIE
QIMSLRAIPGLRVVRPADAHEVKGAWLSALENSGPTALILSRQNLPTLKETKRSFRDGVGRGAYILVKEEGGSPDYTLCA
SGSEVHLAMEVAQSLMALDKRVRVISFPCWELFERQDPEYRESVIGGDLGLRVSIEAGSALGWYKYIGSNGLSIAMDVFG
MSGAPHEVAETCGFTVDSIVQRILSV

Sequences:

>Translated_666_residues
MAGNSELDIDILEKIAGTIKQLSIESIQKASSGHPGMPLGCAEIAAYLYGCVLRYNSKDSQWMNRDRFVLSAGHGSALLY
SCLHLAGFNVRLEDLQQFRQLHSQTPGHPEFRETDGVEATTGPLGQGIGNAVGMALSLKMLGSRFNQSSTSIFDAKVYCL
AGDGCFMEGVSHEACSFAGSLGLDNLILIYDYNEIILDGTLQDVSVEDTKQRFLAYGWDVFEANGHDFEDLHRVFSQIKK
GQQKPTLIIAHTIIGHGSPKEGTNKAHGSPLGEDGVAQTKSFWHLPEEKFFVPSSVKMFFAAKQQEGQKLQEEWQERFRV
WSKRFPEQHQEYLKLTQEISIQDLEVLLNLIDMPESIAGRAASNKVIQVLAENIPSLIGGSADLSSSDGTWIAKETAVNA
SHFQGRNIRYGVREFGMGTIMNGLAYSQVFRPFGGTFLVFSDYLRAAIRLAALSKLPVIYQFTHDSIFVGEDGPTHQPIE
QIMSLRAIPGLRVVRPADAHEVKGAWLSALENSGPTALILSRQNLPTLKETKRSFRDGVGRGAYILVKEEGGSPDYTLCA
SGSEVHLAMEVAQSLMALDKRVRVISFPCWELFERQDPEYRESVIGGDLGLRVSIEAGSALGWYKYIGSNGLSIAMDVFG
MSGAPHEVAETCGFTVDSIVQRILSV
>Mature_665_residues
AGNSELDIDILEKIAGTIKQLSIESIQKASSGHPGMPLGCAEIAAYLYGCVLRYNSKDSQWMNRDRFVLSAGHGSALLYS
CLHLAGFNVRLEDLQQFRQLHSQTPGHPEFRETDGVEATTGPLGQGIGNAVGMALSLKMLGSRFNQSSTSIFDAKVYCLA
GDGCFMEGVSHEACSFAGSLGLDNLILIYDYNEIILDGTLQDVSVEDTKQRFLAYGWDVFEANGHDFEDLHRVFSQIKKG
QQKPTLIIAHTIIGHGSPKEGTNKAHGSPLGEDGVAQTKSFWHLPEEKFFVPSSVKMFFAAKQQEGQKLQEEWQERFRVW
SKRFPEQHQEYLKLTQEISIQDLEVLLNLIDMPESIAGRAASNKVIQVLAENIPSLIGGSADLSSSDGTWIAKETAVNAS
HFQGRNIRYGVREFGMGTIMNGLAYSQVFRPFGGTFLVFSDYLRAAIRLAALSKLPVIYQFTHDSIFVGEDGPTHQPIEQ
IMSLRAIPGLRVVRPADAHEVKGAWLSALENSGPTALILSRQNLPTLKETKRSFRDGVGRGAYILVKEEGGSPDYTLCAS
GSEVHLAMEVAQSLMALDKRVRVISFPCWELFERQDPEYRESVIGGDLGLRVSIEAGSALGWYKYIGSNGLSIAMDVFGM
SGAPHEVAETCGFTVDSIVQRILSV

Specific function: Unknown

COG id: COG0021

COG function: function code G; Transketolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family [H]

Homologues:

Organism=Homo sapiens, GI205277463, Length=676, Percent_Identity=27.3668639053254, Blast_Score=177, Evalue=3e-44,
Organism=Homo sapiens, GI4507521, Length=676, Percent_Identity=27.3668639053254, Blast_Score=177, Evalue=3e-44,
Organism=Homo sapiens, GI133778974, Length=279, Percent_Identity=32.9749103942652, Blast_Score=141, Evalue=2e-33,
Organism=Homo sapiens, GI225637459, Length=585, Percent_Identity=23.7606837606838, Blast_Score=126, Evalue=5e-29,
Organism=Homo sapiens, GI225637463, Length=502, Percent_Identity=24.3027888446215, Blast_Score=114, Evalue=3e-25,
Organism=Homo sapiens, GI225637461, Length=502, Percent_Identity=24.3027888446215, Blast_Score=114, Evalue=4e-25,
Organism=Escherichia coli, GI48994911, Length=658, Percent_Identity=43.7689969604863, Blast_Score=549, Evalue=1e-157,
Organism=Escherichia coli, GI1788808, Length=664, Percent_Identity=43.9759036144578, Blast_Score=545, Evalue=1e-156,
Organism=Caenorhabditis elegans, GI17539652, Length=574, Percent_Identity=28.0487804878049, Blast_Score=175, Evalue=6e-44,
Organism=Saccharomyces cerevisiae, GI6325331, Length=667, Percent_Identity=42.5787106446777, Blast_Score=493, Evalue=1e-140,
Organism=Saccharomyces cerevisiae, GI6319593, Length=671, Percent_Identity=42.9210134128167, Blast_Score=488, Evalue=1e-138,
Organism=Drosophila melanogaster, GI45551847, Length=579, Percent_Identity=27.6338514680484, Blast_Score=172, Evalue=6e-43,
Organism=Drosophila melanogaster, GI45550715, Length=579, Percent_Identity=27.6338514680484, Blast_Score=172, Evalue=6e-43,
Organism=Drosophila melanogaster, GI24666278, Length=576, Percent_Identity=27.0833333333333, Blast_Score=161, Evalue=2e-39,
Organism=Drosophila melanogaster, GI24645119, Length=538, Percent_Identity=27.5092936802974, Blast_Score=154, Evalue=1e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005475
- InterPro:   IPR005478
- InterPro:   IPR020826
- InterPro:   IPR005476
- InterPro:   IPR005474 [H]

Pfam domain/function: PF02779 Transket_pyr; PF02780 Transketolase_C; PF00456 Transketolase_N [H]

EC number: =2.2.1.1 [H]

Molecular weight: Translated: 73174; Mature: 73043

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGNSELDIDILEKIAGTIKQLSIESIQKASSGHPGMPLGCAEIAAYLYGCVLRYNSKDS
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHEECCCCH
QWMNRDRFVLSAGHGSALLYSCLHLAGFNVRLEDLQQFRQLHSQTPGHPEFRETDGVEAT
HHHCCCCEEEECCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
TGPLGQGIGNAVGMALSLKMLGSRFNQSSTSIFDAKVYCLAGDGCFMEGVSHEACSFAGS
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEEECCCHHHCCCCHHHHHHHHC
LGLDNLILIYDYNEIILDGTLQDVSVEDTKQRFLAYGWDVFEANGHDFEDLHRVFSQIKK
CCCCCEEEEEECCEEEEECCCCCCCCHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHHC
GQQKPTLIIAHTIIGHGSPKEGTNKAHGSPLGEDGVAQTKSFWHLPEEKFFVPSSVKMFF
CCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCEECCCHHHHHH
AAKQQEGQKLQEEWQERFRVWSKRFPEQHQEYLKLTQEISIQDLEVLLNLIDMPESIAGR
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHCC
AASNKVIQVLAENIPSLIGGSADLSSSDGTWIAKETAVNASHFQGRNIRYGVREFGMGTI
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEHHHCCCHHHCCCCCCCCCHHHHCHHHH
MNGLAYSQVFRPFGGTFLVFSDYLRAAIRLAALSKLPVIYQFTHDSIFVGEDGPTHQPIE
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCEEEECCCCCCHHHHH
QIMSLRAIPGLRVVRPADAHEVKGAWLSALENSGPTALILSRQNLPTLKETKRSFRDGVG
HHHHHHCCCCCEEECCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHCCCC
RGAYILVKEEGGSPDYTLCASGSEVHLAMEVAQSLMALDKRVRVISFPCWELFERQDPEY
CCEEEEEEECCCCCCEEEEECCCCEEHHHHHHHHHHHHHHCCCEEECCHHHHHHCCCCHH
RESVIGGDLGLRVSIEAGSALGWYKYIGSNGLSIAMDVFGMSGAPHEVAETCGFTVDSIV
HHHHHCCCCCEEEEEECCCCCHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHCCCHHHHH
QRILSV
HHHHCC
>Mature Secondary Structure 
AGNSELDIDILEKIAGTIKQLSIESIQKASSGHPGMPLGCAEIAAYLYGCVLRYNSKDS
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHEECCCCH
QWMNRDRFVLSAGHGSALLYSCLHLAGFNVRLEDLQQFRQLHSQTPGHPEFRETDGVEAT
HHHCCCCEEEECCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
TGPLGQGIGNAVGMALSLKMLGSRFNQSSTSIFDAKVYCLAGDGCFMEGVSHEACSFAGS
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEEECCCHHHCCCCHHHHHHHHC
LGLDNLILIYDYNEIILDGTLQDVSVEDTKQRFLAYGWDVFEANGHDFEDLHRVFSQIKK
CCCCCEEEEEECCEEEEECCCCCCCCHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHHC
GQQKPTLIIAHTIIGHGSPKEGTNKAHGSPLGEDGVAQTKSFWHLPEEKFFVPSSVKMFF
CCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCEECCCHHHHHH
AAKQQEGQKLQEEWQERFRVWSKRFPEQHQEYLKLTQEISIQDLEVLLNLIDMPESIAGR
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHCC
AASNKVIQVLAENIPSLIGGSADLSSSDGTWIAKETAVNASHFQGRNIRYGVREFGMGTI
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEHHHCCCHHHCCCCCCCCCHHHHCHHHH
MNGLAYSQVFRPFGGTFLVFSDYLRAAIRLAALSKLPVIYQFTHDSIFVGEDGPTHQPIE
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEECCEEEECCCCCCHHHHH
QIMSLRAIPGLRVVRPADAHEVKGAWLSALENSGPTALILSRQNLPTLKETKRSFRDGVG
HHHHHHCCCCCEEECCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHCCCC
RGAYILVKEEGGSPDYTLCASGSEVHLAMEVAQSLMALDKRVRVISFPCWELFERQDPEY
CCEEEEEEECCCCCCEEEEECCCCEEHHHHHHHHHHHHHHCCCEEECCHHHHHHCCCCHH
RESVIGGDLGLRVSIEAGSALGWYKYIGSNGLSIAMDVFGMSGAPHEVAETCGFTVDSIV
HHHHHCCCCCEEEEEECCCCCHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHCCCHHHHH
QRILSV
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]