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Identifier: 15834737

GI number: 15834737

Start: 130662

End: 133046

Strand: Reverse

Name: Not Available

Synonym: TC0112

Alternate gene names: 15834737

Gene position: 133046-130662 (Counterclockwise)

Preceding gene: 29337301

Following gene: 15834736

Centisome position: 12.4

GC content: 41.72

Gene sequence:

>2385_bases
ATGAGAAAAGAACGAAAGAAAGCCAGCGTTTCTCTTTCTCCACAAACAGTCTTTGCTATCAAAACCTGCATCTATCTAGC
CTTGGCCTGTTTCTCAGGACTTAGTTTATGGAGCTTTCAGCATAACCAACCTTACACGCAAAATTGGATAGGTTTGCTCG
GATGGTCTCTTAGTTCTTTCCTATTATATAACTTTGGAGTAGCCGCCTTTCTAATCCCTCTTTACTTCGGCTTTCTTTCT
TTCTTGAATATGAAAAAAACTCCCGCCCCACTAGCCTTTAGAAAGGCGGTAGCTTTCGGCACTGTTCCTGTTTGTTGCGC
CATACTGTTATCCATGGTTTCTCCTGCACAAAATCTTCCCCAGTTTTTGGCTACAAGAGTTCCTATGGTTGTTATGGACC
TTCAACCTCCAAAAGCTTATTTAGGGGGCATTCCTTTTTACCTGCTATATGATGGGAACTCTTTTTCCTTAAAACTATTA
ATTGGCGCAGTGGGAACTGGATTAATTTTTCTCGCTATATTGCTTTGCGCAATCTGCTACCTTATTCCCAAGTCTTTTGT
GTTAAAAAAAAAAGCACTTCTAGACGCTCTCCTCAAATTTCTCAAAAACAAATCTTACGCATGTTGGAGCGCCTGCAAAA
AGCTTTTAAAAAATCTTGTTAATAATAAGTCCTATTGTCCCGAGCCTTCACTTCGAGTACCCGCTCCATCTTCTTTCGCC
AAAAAAGAAGTTTTAAAACTTCCAACCCCCGTGATTTCCCTCCCTCTGGAAAATAAAGACCTCCATGATGGCGACTCCTC
TAATCGCACTATTTTTCTCTCTCCACCACATCCTGCGAAAAGAACTCTGGCTCCTCAAAAGAAACCGGATCTTCCAGACC
TTTTACAAAAAAGAACTTCTTCAACGCCTATACCATCTTCATCGCCATCTCCCTTTATAGTGGCAGGAGAGGCTCCCGAT
TTACCGCAATACCATCTGTTAAGTAAACGGAACATACGACGGCCGGAATCGCTTTTAGAAGAATTAAAAAAGAAAGCCGC
TATTTTACAACAAACTTTGGCAAGTTTTGGCATAGATGCTTCCATTGGGAACATTTGCTCCGGCCCCACCCTTGCAGCAT
TTGAAGTTCTCCCTAATACAGGAGTTAAAGTACAGAAAATCAAGGCTCTAGAAAATGATATCGCGTTAAATTTACAAGCT
TCCAGCATTCGCATTATTGCTCCAATCCCAGGGAAGGCCGCTGTTGGAATTGAAATCCCTAACCCAGATCCCCAACCTGT
AAACTTCCGTGATTTACTAGAAGACTACCAAAAAGGTACCCAGAGACTTCAAGTTCCTTTGCTCCTTGGAAAAAAAGCTA
ATGGAGATAATTTTTGGACTGACCTAGCAACCATGCCTCACTTAATTATTGCCGGGACCACTGGATCTGGAAAATCTGTC
TGTATCAACACAATTGTCATGTCTCTCATCATGACTTCTCCCCCTACAGATGTTAAACTTGTGATTGTAGACCCTAAAAA
AGTAGAATTGACTGGTTACTCACAGCTCCCTCATATGTTAACGCCCGTTATTACGGAGTCCAAAGAAGCTCATAGCGCCT
TAATTTGGCTTGTTCGAGAGATGGAGCTTCGCTATGAAATCCTACGATTTTTAGGGCTACGGAATATCCAATCATTCAAC
TCTCGAACTCGCAATGTAGATATTGAAGCTTCTTACGACAAAGAAATCCCAGAAAAAATGCCTTTCATTGTCGGTATTAT
TGATGAGCTCTCAGATTTACTTCTTTCTTCCTCTCATGACATCGAAACGCCTATAGTGCGTTTAGCTCAAATGGCTAGAG
CCGTGGGGATTCACCTCATTTTAGCAACACAACGTCCTTCTCGAGACGTCATCACAGGATTAATCAAAGCAAACTTCCCG
TCTCGAATTGCTTTCAAAGTCGCGAACAAAGTGAATAGTCAAATTATTATCGACGAACCGGGAGCAGAAAATTTGATGGG
GAACGGAGACATGCTAGTGGTTTCTCCAGGATCCTTTGCACCTTTGCGCGTACAGGGAGCCTATATTTGCGATGACGATA
TTAACAAAGTCATTAAAGATTTATGTTCAAGATTCCCTTGTAAGTATGTAATTCCTTCATTTGATACGTACGACGACTCC
TCTTCTATGGATCCAGAGAGTCTAGATCCTTTATTTAATCAGGCAAAAACTCTTGTATTGCAAACAGGGAATGCCTCAAC
AACTTTCCTCCAAAGAAAACTCAAAATTGGCTACGCTAGAGCAGCAAGTATTATTGACCAGCTGGAGGAAGCGAGAATTG
TAGGCCCTTCAGAAGGAGCCAAACCACGTCAAATACTGGTCCAACTATCAAATCAGGAAGATTAA

Upstream 100 bases:

>100_bases
GCGCGTTGGAATATTGCGCTTTATCAACAAGCCATATCTCCATACGAATGCTATTCCTTGTAAGAGTCCGTATCAATGTA
CAGTGTATAAGAGAGGAATC

Downstream 100 bases:

>100_bases
TCAATGGAAGGCTTTTTCCCCATAGCTTCGGGATCCAAGGGCAATTGCGCCTATCTAGGGACAGAGGCATGCAAAATACT
CGTGGACCTAGGGATTAGCA

Product: cell division protein FtsK, putative

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 794; Mature: 794

Protein sequence:

>794_residues
MRKERKKASVSLSPQTVFAIKTCIYLALACFSGLSLWSFQHNQPYTQNWIGLLGWSLSSFLLYNFGVAAFLIPLYFGFLS
FLNMKKTPAPLAFRKAVAFGTVPVCCAILLSMVSPAQNLPQFLATRVPMVVMDLQPPKAYLGGIPFYLLYDGNSFSLKLL
IGAVGTGLIFLAILLCAICYLIPKSFVLKKKALLDALLKFLKNKSYACWSACKKLLKNLVNNKSYCPEPSLRVPAPSSFA
KKEVLKLPTPVISLPLENKDLHDGDSSNRTIFLSPPHPAKRTLAPQKKPDLPDLLQKRTSSTPIPSSSPSPFIVAGEAPD
LPQYHLLSKRNIRRPESLLEELKKKAAILQQTLASFGIDASIGNICSGPTLAAFEVLPNTGVKVQKIKALENDIALNLQA
SSIRIIAPIPGKAAVGIEIPNPDPQPVNFRDLLEDYQKGTQRLQVPLLLGKKANGDNFWTDLATMPHLIIAGTTGSGKSV
CINTIVMSLIMTSPPTDVKLVIVDPKKVELTGYSQLPHMLTPVITESKEAHSALIWLVREMELRYEILRFLGLRNIQSFN
SRTRNVDIEASYDKEIPEKMPFIVGIIDELSDLLLSSSHDIETPIVRLAQMARAVGIHLILATQRPSRDVITGLIKANFP
SRIAFKVANKVNSQIIIDEPGAENLMGNGDMLVVSPGSFAPLRVQGAYICDDDINKVIKDLCSRFPCKYVIPSFDTYDDS
SSMDPESLDPLFNQAKTLVLQTGNASTTFLQRKLKIGYARAASIIDQLEEARIVGPSEGAKPRQILVQLSNQED

Sequences:

>Translated_794_residues
MRKERKKASVSLSPQTVFAIKTCIYLALACFSGLSLWSFQHNQPYTQNWIGLLGWSLSSFLLYNFGVAAFLIPLYFGFLS
FLNMKKTPAPLAFRKAVAFGTVPVCCAILLSMVSPAQNLPQFLATRVPMVVMDLQPPKAYLGGIPFYLLYDGNSFSLKLL
IGAVGTGLIFLAILLCAICYLIPKSFVLKKKALLDALLKFLKNKSYACWSACKKLLKNLVNNKSYCPEPSLRVPAPSSFA
KKEVLKLPTPVISLPLENKDLHDGDSSNRTIFLSPPHPAKRTLAPQKKPDLPDLLQKRTSSTPIPSSSPSPFIVAGEAPD
LPQYHLLSKRNIRRPESLLEELKKKAAILQQTLASFGIDASIGNICSGPTLAAFEVLPNTGVKVQKIKALENDIALNLQA
SSIRIIAPIPGKAAVGIEIPNPDPQPVNFRDLLEDYQKGTQRLQVPLLLGKKANGDNFWTDLATMPHLIIAGTTGSGKSV
CINTIVMSLIMTSPPTDVKLVIVDPKKVELTGYSQLPHMLTPVITESKEAHSALIWLVREMELRYEILRFLGLRNIQSFN
SRTRNVDIEASYDKEIPEKMPFIVGIIDELSDLLLSSSHDIETPIVRLAQMARAVGIHLILATQRPSRDVITGLIKANFP
SRIAFKVANKVNSQIIIDEPGAENLMGNGDMLVVSPGSFAPLRVQGAYICDDDINKVIKDLCSRFPCKYVIPSFDTYDDS
SSMDPESLDPLFNQAKTLVLQTGNASTTFLQRKLKIGYARAASIIDQLEEARIVGPSEGAKPRQILVQLSNQED
>Mature_794_residues
MRKERKKASVSLSPQTVFAIKTCIYLALACFSGLSLWSFQHNQPYTQNWIGLLGWSLSSFLLYNFGVAAFLIPLYFGFLS
FLNMKKTPAPLAFRKAVAFGTVPVCCAILLSMVSPAQNLPQFLATRVPMVVMDLQPPKAYLGGIPFYLLYDGNSFSLKLL
IGAVGTGLIFLAILLCAICYLIPKSFVLKKKALLDALLKFLKNKSYACWSACKKLLKNLVNNKSYCPEPSLRVPAPSSFA
KKEVLKLPTPVISLPLENKDLHDGDSSNRTIFLSPPHPAKRTLAPQKKPDLPDLLQKRTSSTPIPSSSPSPFIVAGEAPD
LPQYHLLSKRNIRRPESLLEELKKKAAILQQTLASFGIDASIGNICSGPTLAAFEVLPNTGVKVQKIKALENDIALNLQA
SSIRIIAPIPGKAAVGIEIPNPDPQPVNFRDLLEDYQKGTQRLQVPLLLGKKANGDNFWTDLATMPHLIIAGTTGSGKSV
CINTIVMSLIMTSPPTDVKLVIVDPKKVELTGYSQLPHMLTPVITESKEAHSALIWLVREMELRYEILRFLGLRNIQSFN
SRTRNVDIEASYDKEIPEKMPFIVGIIDELSDLLLSSSHDIETPIVRLAQMARAVGIHLILATQRPSRDVITGLIKANFP
SRIAFKVANKVNSQIIIDEPGAENLMGNGDMLVVSPGSFAPLRVQGAYICDDDINKVIKDLCSRFPCKYVIPSFDTYDDS
SSMDPESLDPLFNQAKTLVLQTGNASTTFLQRKLKIGYARAASIIDQLEEARIVGPSEGAKPRQILVQLSNQED

Specific function: DNA motor protein, which is both required to move DNA out of the region of the septum during cell division and for the septum formation. Tracks DNA in an ATP-dependent manner by generating positive supercoils in front of it and negative supercoils behind

COG id: COG1674

COG function: function code D; DNA segregation ATPase FtsK/SpoIIIE and related proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein; Cytoplasmic side. Note=Located at the septum. The large C-terminal part of the protein is cytoplasmic (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FtsK domain [H]

Homologues:

Organism=Escherichia coli, GI1787117, Length=464, Percent_Identity=40.948275862069, Blast_Score=357, Evalue=2e-99,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR018541
- InterPro:   IPR002543 [H]

Pfam domain/function: PF09397 Ftsk_gamma; PF01580 FtsK_SpoIIIE [H]

EC number: NA

Molecular weight: Translated: 87317; Mature: 87317

Theoretical pI: Translated: 9.49; Mature: 9.49

Prosite motif: PS50901 FTSK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKERKKASVSLSPQTVFAIKTCIYLALACFSGLSLWSFQHNQPYTQNWIGLLGWSLSSF
CCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHH
LLYNFGVAAFLIPLYFGFLSFLNMKKTPAPLAFRKAVAFGTVPVCCAILLSMVSPAQNLP
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHCCHHHHH
QFLATRVPMVVMDLQPPKAYLGGIPFYLLYDGNSFSLKLLIGAVGTGLIFLAILLCAICY
HHHHHCCCEEEEECCCCHHHHCCCCEEEEECCCCEEEEEEEHHHHHHHHHHHHHHHHHHH
LIPKSFVLKKKALLDALLKFLKNKSYACWSACKKLLKNLVNNKSYCPEPSLRVPAPSSFA
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHH
KKEVLKLPTPVISLPLENKDLHDGDSSNRTIFLSPPHPAKRTLAPQKKPDLPDLLQKRTS
HHHHHHCCCCEEECCCCCCCCCCCCCCCCEEEECCCCCHHHCCCCCCCCCCHHHHHHHCC
STPIPSSSPSPFIVAGEAPDLPQYHLLSKRNIRRPESLLEELKKKAAILQQTLASFGIDA
CCCCCCCCCCCEEEECCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
SIGNICSGPTLAAFEVLPNTGVKVQKIKALENDIALNLQASSIRIIAPIPGKAAVGIEIP
CCCCCCCCCCEEEEEECCCCCCCHHHHHHHHCCEEEEEEECCEEEEEECCCCEEEEEECC
NPDPQPVNFRDLLEDYQKGTQRLQVPLLLGKKANGDNFWTDLATMPHLIIAGTTGSGKSV
CCCCCCCCHHHHHHHHHHHHHHEEEEEEECCCCCCCCHHHHHHCCCEEEEEECCCCCCHH
CINTIVMSLIMTSPPTDVKLVIVDPKKVELTGYSQLPHMLTPVITESKEAHSALIWLVRE
HHHHHHHHHHHCCCCCCEEEEEECCCEEEECCCHHCHHHHHHHHCCCCHHHHHHHHHHHH
MELRYEILRFLGLRNIQSFNSRTRNVDIEASYDKEIPEKMPFIVGIIDELSDLLLSSSHD
HHHHHHHHHHHHHHHHHHHCCHHCEEEEEECCCCCCHHHCCHHHHHHHHHHHHHHCCCCC
IETPIVRLAQMARAVGIHLILATQRPSRDVITGLIKANFPSRIAFKVANKVNSQIIIDEP
CHHHHHHHHHHHHHHCEEEEEECCCCCHHHHHHHHHCCCCHHHHHHHHHHCCCEEEEECC
GAENLMGNGDMLVVSPGSFAPLRVQGAYICDDDINKVIKDLCSRFPCKYVIPSFDTYDDS
CCCCCCCCCCEEEECCCCCCCEEEECEEECCHHHHHHHHHHHHHCCCCEECCCCCCCCCC
SSMDPESLDPLFNQAKTLVLQTGNASTTFLQRKLKIGYARAASIIDQLEEARIVGPSEGA
CCCCHHHHHHHHHHCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCEEECCCCCC
KPRQILVQLSNQED
CHHHHHEEECCCCC
>Mature Secondary Structure
MRKERKKASVSLSPQTVFAIKTCIYLALACFSGLSLWSFQHNQPYTQNWIGLLGWSLSSF
CCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHH
LLYNFGVAAFLIPLYFGFLSFLNMKKTPAPLAFRKAVAFGTVPVCCAILLSMVSPAQNLP
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHCCHHHHH
QFLATRVPMVVMDLQPPKAYLGGIPFYLLYDGNSFSLKLLIGAVGTGLIFLAILLCAICY
HHHHHCCCEEEEECCCCHHHHCCCCEEEEECCCCEEEEEEEHHHHHHHHHHHHHHHHHHH
LIPKSFVLKKKALLDALLKFLKNKSYACWSACKKLLKNLVNNKSYCPEPSLRVPAPSSFA
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHH
KKEVLKLPTPVISLPLENKDLHDGDSSNRTIFLSPPHPAKRTLAPQKKPDLPDLLQKRTS
HHHHHHCCCCEEECCCCCCCCCCCCCCCCEEEECCCCCHHHCCCCCCCCCCHHHHHHHCC
STPIPSSSPSPFIVAGEAPDLPQYHLLSKRNIRRPESLLEELKKKAAILQQTLASFGIDA
CCCCCCCCCCCEEEECCCCCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
SIGNICSGPTLAAFEVLPNTGVKVQKIKALENDIALNLQASSIRIIAPIPGKAAVGIEIP
CCCCCCCCCCEEEEEECCCCCCCHHHHHHHHCCEEEEEEECCEEEEEECCCCEEEEEECC
NPDPQPVNFRDLLEDYQKGTQRLQVPLLLGKKANGDNFWTDLATMPHLIIAGTTGSGKSV
CCCCCCCCHHHHHHHHHHHHHHEEEEEEECCCCCCCCHHHHHHCCCEEEEEECCCCCCHH
CINTIVMSLIMTSPPTDVKLVIVDPKKVELTGYSQLPHMLTPVITESKEAHSALIWLVRE
HHHHHHHHHHHCCCCCCEEEEEECCCEEEECCCHHCHHHHHHHHCCCCHHHHHHHHHHHH
MELRYEILRFLGLRNIQSFNSRTRNVDIEASYDKEIPEKMPFIVGIIDELSDLLLSSSHD
HHHHHHHHHHHHHHHHHHHCCHHCEEEEEECCCCCCHHHCCHHHHHHHHHHHHHHCCCCC
IETPIVRLAQMARAVGIHLILATQRPSRDVITGLIKANFPSRIAFKVANKVNSQIIIDEP
CHHHHHHHHHHHHHHCEEEEEECCCCCHHHHHHHHHCCCCHHHHHHHHHHCCCEEEEECC
GAENLMGNGDMLVVSPGSFAPLRVQGAYICDDDINKVIKDLCSRFPCKYVIPSFDTYDDS
CCCCCCCCCCEEEECCCCCCCEEEECEEECCHHHHHHHHHHHHHCCCCEECCCCCCCCCC
SSMDPESLDPLFNQAKTLVLQTGNASTTFLQRKLKIGYARAASIIDQLEEARIVGPSEGA
CCCCHHHHHHHHHHCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCEEECCCCCC
KPRQILVQLSNQED
CHHHHHEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9784136; 11532140 [H]