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Identifier: 15834733

GI number: 15834733

Start: 127321

End: 128688

Strand: Direct

Name: Not Available

Synonym: TC0108

Alternate gene names: 15834733

Gene position: 127321-128688 (Clockwise)

Preceding gene: 15834732

Following gene: 15834734

Centisome position: 11.87

GC content: 40.94

Gene sequence:

>1368_bases
ATGTTACGGTTTTTAGAACAAATTAATAGTTTTTTAACTTTTTTCTGCGTGTTCCCCCTGATTCTTTTCTTGGGAGGAAT
ATTGACATGGAAACTGCGGGGGCTACAGTTCACTTCTTTAGGAACAAGTTTTCGCTTGATGCTAAGTAATCAACAGGAAC
CCTCTGTCTCTGAGGGAAAAGGGGTTTCTCGTTACGAGGCTGTTGCTGGTATGTTAGCTGGTAATTTTGGAACAGGTAAT
ATAGCAGGGATGGCGATCGCTGTTGTTAATGGGGGACCTGGAGCTTTACTTTGGATCTGGATTGTTACTTTTTTGGCAGC
AATCGTTCAATACGCAGGGGCTTTCCTTGGATGTAAGTATCGCCAGTTTCAAGCGGCATCTCAGGAATATATTGGAGGAC
CAATAGCTTGTTTGGGATATAAAATGAAAAGCCGTTTCTTAGCTGGAGCCTTTTGTATAGCTGGTTTAATCTCTGCTTTT
TTTGCAGGGAATTTTGTTCAAGTTAACGGAATTGTTTCTCTGTGTGCAGATAGTGTCTATACAAAAATTTTGGCAGGGGT
GTTGTTAGCGCTTTCTATTTATCCTGTTTTAGCTGGAGGAAATACTCGAGTTCTCCGCTTTTCTGCGAAAGCAATTCCTT
TTGTAGCGGGCTTCTATTTCCTTTTCTCCGTCATAGTTTTAGCGATTCATTGTGATAAAATTCTTCCGGCTTTGCACCTC
GTTTTCTCTTCTGCTTTAGGTATAAAGGCTGGAATTGCAGGAATTGGCGGTTATACGATAGGACAAGTGATTTCAACAGG
ATTGAATCGAGCTATTATGGCGACGGATTGTGGAAATGGTATGGTTTCCATTCTACAATCCAATTCTAAAAGCTCTAACC
CAGTTGCGGATGGATTAGTAACTCTTCTCCCTCCTGTAATTGTCGCTGTTGTTTGTTCTATCACAATGATGGTTCTTCTT
GTGACAGGAGCTTATGAGTCCGGAGAACTAGGAGTTTTGATGGTTATGCATGCTTTCAAATCCTCTTTAGGTATGTGGGG
AGGAAGTGTTGTCTTCATATCTATGCTCTTATTTGGGTATACAACAGTGTTATCATGGTTTGCTTGCGCAGAAAAAAGTT
TAGAATATATGATCCCAGGAAGGCGAGCTAACCTATGGTTAAAGGCTGTTTATATATTGGTGATCCCTATGGGAGGTGTT
TTAGGCATGCAATCTGTCTGGGCACTATCTGATTTAGGTTTCTGTGGGATGGTAATTTTCAATGCGATCAGTTTGATTGC
TTTGTTTAAGGAGGTAATTGCTACTCGCGATGAAGTAGCTCTTCTTCGTAAAAAAGCAACAGCTCAGGTTGATCCTTTAA
GACAGTAG

Upstream 100 bases:

>100_bases
TTGTTCTATAGGCCCCCTTTCCCCAGATAGGAGAAAGGGGGCTTTTGTATTATTCCGCTTATTTGCCTCCGAGGCGGATG
CAAAATAAAAGAGTAGGACG

Downstream 100 bases:

>100_bases
TGCAAGCATAGGGCCGCTTTATTATAAAAAGCGGCCAAGCCTCTTCTTCAAATATAGGAGATCTTTTATGCAACTTACTT
CGCAGGCTTTTTCTTATGGC

Product: sodium/alanine symporter family protein

Products: Na (I) [Cytoplasm]; L-alanine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 455; Mature: 455

Protein sequence:

>455_residues
MLRFLEQINSFLTFFCVFPLILFLGGILTWKLRGLQFTSLGTSFRLMLSNQQEPSVSEGKGVSRYEAVAGMLAGNFGTGN
IAGMAIAVVNGGPGALLWIWIVTFLAAIVQYAGAFLGCKYRQFQAASQEYIGGPIACLGYKMKSRFLAGAFCIAGLISAF
FAGNFVQVNGIVSLCADSVYTKILAGVLLALSIYPVLAGGNTRVLRFSAKAIPFVAGFYFLFSVIVLAIHCDKILPALHL
VFSSALGIKAGIAGIGGYTIGQVISTGLNRAIMATDCGNGMVSILQSNSKSSNPVADGLVTLLPPVIVAVVCSITMMVLL
VTGAYESGELGVLMVMHAFKSSLGMWGGSVVFISMLLFGYTTVLSWFACAEKSLEYMIPGRRANLWLKAVYILVIPMGGV
LGMQSVWALSDLGFCGMVIFNAISLIALFKEVIATRDEVALLRKKATAQVDPLRQ

Sequences:

>Translated_455_residues
MLRFLEQINSFLTFFCVFPLILFLGGILTWKLRGLQFTSLGTSFRLMLSNQQEPSVSEGKGVSRYEAVAGMLAGNFGTGN
IAGMAIAVVNGGPGALLWIWIVTFLAAIVQYAGAFLGCKYRQFQAASQEYIGGPIACLGYKMKSRFLAGAFCIAGLISAF
FAGNFVQVNGIVSLCADSVYTKILAGVLLALSIYPVLAGGNTRVLRFSAKAIPFVAGFYFLFSVIVLAIHCDKILPALHL
VFSSALGIKAGIAGIGGYTIGQVISTGLNRAIMATDCGNGMVSILQSNSKSSNPVADGLVTLLPPVIVAVVCSITMMVLL
VTGAYESGELGVLMVMHAFKSSLGMWGGSVVFISMLLFGYTTVLSWFACAEKSLEYMIPGRRANLWLKAVYILVIPMGGV
LGMQSVWALSDLGFCGMVIFNAISLIALFKEVIATRDEVALLRKKATAQVDPLRQ
>Mature_455_residues
MLRFLEQINSFLTFFCVFPLILFLGGILTWKLRGLQFTSLGTSFRLMLSNQQEPSVSEGKGVSRYEAVAGMLAGNFGTGN
IAGMAIAVVNGGPGALLWIWIVTFLAAIVQYAGAFLGCKYRQFQAASQEYIGGPIACLGYKMKSRFLAGAFCIAGLISAF
FAGNFVQVNGIVSLCADSVYTKILAGVLLALSIYPVLAGGNTRVLRFSAKAIPFVAGFYFLFSVIVLAIHCDKILPALHL
VFSSALGIKAGIAGIGGYTIGQVISTGLNRAIMATDCGNGMVSILQSNSKSSNPVADGLVTLLPPVIVAVVCSITMMVLL
VTGAYESGELGVLMVMHAFKSSLGMWGGSVVFISMLLFGYTTVLSWFACAEKSLEYMIPGRRANLWLKAVYILVIPMGGV
LGMQSVWALSDLGFCGMVIFNAISLIALFKEVIATRDEVALLRKKATAQVDPLRQ

Specific function: Unknown

COG id: COG1115

COG function: function code E; Na+/alanine symporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:alanine (SAF) symporter family [H]

Homologues:

Organism=Escherichia coli, GI1786188, Length=464, Percent_Identity=24.7844827586207, Blast_Score=124, Evalue=1e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001463 [H]

Pfam domain/function: PF01235 Na_Ala_symp [H]

EC number: NA

Molecular weight: Translated: 48494; Mature: 48494

Theoretical pI: Translated: 9.33; Mature: 9.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRFLEQINSFLTFFCVFPLILFLGGILTWKLRGLQFTSLGTSFRLMLSNQQEPSVSEGK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCEEEEEECCCCCCCCCCCC
GVSRYEAVAGMLAGNFGTGNIAGMAIAVVNGGPGALLWIWIVTFLAAIVQYAGAFLGCKY
CCHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCHH
RQFQAASQEYIGGPIACLGYKMKSRFLAGAFCIAGLISAFFAGNFVQVNGIVSLCADSVY
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHH
TKILAGVLLALSIYPVLAGGNTRVLRFSAKAIPFVAGFYFLFSVIVLAIHCDKILPALHL
HHHHHHHHHHHHHHHHEECCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VFSSALGIKAGIAGIGGYTIGQVISTGLNRAIMATDCGNGMVSILQSNSKSSNPVADGLV
HHHHHHHHHHHHHHCCHHHHHHHHHHCCCCEEEEECCCCHHHHHHHCCCCCCCCHHHHHH
TLLPPVIVAVVCSITMMVLLVTGAYESGELGVLMVMHAFKSSLGMWGGSVVFISMLLFGY
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
TTVLSWFACAEKSLEYMIPGRRANLWLKAVYILVIPMGGVLGMQSVWALSDLGFCGMVIF
HHHHHHHHHHHHCHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHH
NAISLIALFKEVIATRDEVALLRKKATAQVDPLRQ
HHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MLRFLEQINSFLTFFCVFPLILFLGGILTWKLRGLQFTSLGTSFRLMLSNQQEPSVSEGK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCEEEEEECCCCCCCCCCCC
GVSRYEAVAGMLAGNFGTGNIAGMAIAVVNGGPGALLWIWIVTFLAAIVQYAGAFLGCKY
CCHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCHH
RQFQAASQEYIGGPIACLGYKMKSRFLAGAFCIAGLISAFFAGNFVQVNGIVSLCADSVY
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHHHHH
TKILAGVLLALSIYPVLAGGNTRVLRFSAKAIPFVAGFYFLFSVIVLAIHCDKILPALHL
HHHHHHHHHHHHHHHHEECCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VFSSALGIKAGIAGIGGYTIGQVISTGLNRAIMATDCGNGMVSILQSNSKSSNPVADGLV
HHHHHHHHHHHHHHCCHHHHHHHHHHCCCCEEEEECCCCHHHHHHHCCCCCCCCHHHHHH
TLLPPVIVAVVCSITMMVLLVTGAYESGELGVLMVMHAFKSSLGMWGGSVVFISMLLFGY
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
TTVLSWFACAEKSLEYMIPGRRANLWLKAVYILVIPMGGVLGMQSVWALSDLGFCGMVIF
HHHHHHHHHHHHCHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHH
NAISLIALFKEVIATRDEVALLRKKATAQVDPLRQ
HHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Na (I) [Periplasm]; L-alanine [Periplasm] [C]

Specific reaction: Na (I) [Periplasm] + L-alanine [Periplasm] = Na (I) [Cytoplasm] + L-alanine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]