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Identifier: 15834724

GI number: 15834724

Start: 116534

End: 117673

Strand: Reverse

Name: Not Available

Synonym: TC0099

Alternate gene names: 15834724

Gene position: 117673-116534 (Counterclockwise)

Preceding gene: 15834725

Following gene: 15834720

Centisome position: 10.97

GC content: 41.75

Gene sequence:

>1140_bases
ATGAAAAACACCAAATACTTACGCCAAGTGAACTTATGGATCTTTGTAGTGATCATTTTGCTCATGAGCATAAGTGTTAT
TGTGATCTCATCTCAAGATCCCTCTTCCATGTTGGTCCATACCTCGCGAGGACTCTTCTCCGCAAAAAGTAAAATACAAT
TGCGCCATTTTGCCTTGGGATGGTTCGCCTATTTTATTTGCTTATATGTGGACTATCACCAATTTAAAAGATGGGCGTGG
GTTCTCTATGCTCTTATTCTCTTTAGCCTCATCGGCTTGTTTTTCGTTCCGGCAGTGCAAAACGTTCATCGCTGGTATCG
CATCCCTATTATTAACCTTAGCGTTCAACCTTCGGAATACGCTAAGCTTGTTGTCGTCATTATGTTGAGCTACATGCTAG
AAATGCGTAAAGCTCGCATCTCTTCTAAAACAACAGCTTTTATTGCCTGTATCATAGTTGGAATCCCTTTTCTTCTTATC
CTCAAAGAACCCGATCTTGGCACCGCCCTAGTACTATGTCCGATAGCCCTCACGATTTTTTACATAGGGAACATCTATCC
TCCTTTGGTAAAAATTTGTTCGATCTTTGCTGCTTTAGGAATGCTTTGCTCTTTACTGATTTTCTCTGGGATTATTCCTC
ATGATACAGTTAAACCTTATGCTCTTAGAGTATTAAAAGAATATCAATACGAACGCTTAAGTCCTTCCAATCACCACCAA
CGAGCCTCCTTAATCTCTATCGGAGTCGGAGGATTAAAAGGCCAAGGATGGAAATCTGGAGAATTTGCAGGTAGGGGCTG
GCTTCCTTATGGCTATACGGACTCGGTATTCCCCGCTATAGGAGAAGAGTTCGGATTACTGGGACTTTTATTTGTACTAT
GGCTGTTTTATAACCTAGTCTGTTTTGGATGTCGCACCGTTGCGGTTGCGGTTGATGATTTTGGACGATTTCTAGCAGGG
GGAGTCACAGTGCATCTTGTCATGCACGTACTCATCAATGTTAGTATGATGAGTGGGCTCTTACCCATTACGGGAGTTCC
CCTTGTCCTAATTTCTTATGGAGGATCTTCTGTAATTTCTACAATGGCCTCTCTAGGTATCTTGCAAAGCATTTATAGTC
GACGCTTTGCAAAATATTAA

Upstream 100 bases:

>100_bases
AAGGAAGTACCGTGATTGTGGGCCTTAATGCTCTTCGCCTTTTAAAAAACACGTGATTTCCTTGTGATTTTTAGAGAAAG
GAACGCATAACATCCCTTGT

Downstream 100 bases:

>100_bases
TACAAGCTTACTTAGATCCCCATAAGGGAAGCTCTTGTATGAGGTATTTAATTTCCTTGGCAAGTTGATAAACTTGCTCT
TCCATATCTAAAGATTCCCC

Product: cell shape-determining protein MrdB, putative

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 379; Mature: 379

Protein sequence:

>379_residues
MKNTKYLRQVNLWIFVVIILLMSISVIVISSQDPSSMLVHTSRGLFSAKSKIQLRHFALGWFAYFICLYVDYHQFKRWAW
VLYALILFSLIGLFFVPAVQNVHRWYRIPIINLSVQPSEYAKLVVVIMLSYMLEMRKARISSKTTAFIACIIVGIPFLLI
LKEPDLGTALVLCPIALTIFYIGNIYPPLVKICSIFAALGMLCSLLIFSGIIPHDTVKPYALRVLKEYQYERLSPSNHHQ
RASLISIGVGGLKGQGWKSGEFAGRGWLPYGYTDSVFPAIGEEFGLLGLLFVLWLFYNLVCFGCRTVAVAVDDFGRFLAG
GVTVHLVMHVLINVSMMSGLLPITGVPLVLISYGGSSVISTMASLGILQSIYSRRFAKY

Sequences:

>Translated_379_residues
MKNTKYLRQVNLWIFVVIILLMSISVIVISSQDPSSMLVHTSRGLFSAKSKIQLRHFALGWFAYFICLYVDYHQFKRWAW
VLYALILFSLIGLFFVPAVQNVHRWYRIPIINLSVQPSEYAKLVVVIMLSYMLEMRKARISSKTTAFIACIIVGIPFLLI
LKEPDLGTALVLCPIALTIFYIGNIYPPLVKICSIFAALGMLCSLLIFSGIIPHDTVKPYALRVLKEYQYERLSPSNHHQ
RASLISIGVGGLKGQGWKSGEFAGRGWLPYGYTDSVFPAIGEEFGLLGLLFVLWLFYNLVCFGCRTVAVAVDDFGRFLAG
GVTVHLVMHVLINVSMMSGLLPITGVPLVLISYGGSSVISTMASLGILQSIYSRRFAKY
>Mature_379_residues
MKNTKYLRQVNLWIFVVIILLMSISVIVISSQDPSSMLVHTSRGLFSAKSKIQLRHFALGWFAYFICLYVDYHQFKRWAW
VLYALILFSLIGLFFVPAVQNVHRWYRIPIINLSVQPSEYAKLVVVIMLSYMLEMRKARISSKTTAFIACIIVGIPFLLI
LKEPDLGTALVLCPIALTIFYIGNIYPPLVKICSIFAALGMLCSLLIFSGIIPHDTVKPYALRVLKEYQYERLSPSNHHQ
RASLISIGVGGLKGQGWKSGEFAGRGWLPYGYTDSVFPAIGEEFGLLGLLFVLWLFYNLVCFGCRTVAVAVDDFGRFLAG
GVTVHLVMHVLINVSMMSGLLPITGVPLVLISYGGSSVISTMASLGILQSIYSRRFAKY

Specific function: This is one of the proteins responsible for the rod shape of the cell. It is required for the expression of the enzymatic activity of PBP2, which is thought to synthesize peptidoglycan in the step of initiation of cell elongation [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786853, Length=342, Percent_Identity=30.4093567251462, Blast_Score=132, Evalue=4e-32,
Organism=Escherichia coli, GI1786277, Length=365, Percent_Identity=26.5753424657534, Blast_Score=89, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR011923 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 42431; Mature: 42431

Theoretical pI: Translated: 9.85; Mature: 9.85

Prosite motif: PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNTKYLRQVNLWIFVVIILLMSISVIVISSQDPSSMLVHTSRGLFSAKSKIQLRHFALG
CCCHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCHHHEECCCCHHHHHHHHHHHHHHHH
WFAYFICLYVDYHQFKRWAWVLYALILFSLIGLFFVPAVQNVHRWYRIPIINLSVQPSEY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCHHH
AKLVVVIMLSYMLEMRKARISSKTTAFIACIIVGIPFLLILKEPDLGTALVLCPIALTIF
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHH
YIGNIYPPLVKICSIFAALGMLCSLLIFSGIIPHDTVKPYALRVLKEYQYERLSPSNHHQ
HHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHH
RASLISIGVGGLKGQGWKSGEFAGRGWLPYGYTDSVFPAIGEEFGLLGLLFVLWLFYNLV
HHHHHEECCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
CFGCRTVAVAVDDFGRFLAGGVTVHLVMHVLINVSMMSGLLPITGVPLVLISYGGSSVIS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHH
TMASLGILQSIYSRRFAKY
HHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKNTKYLRQVNLWIFVVIILLMSISVIVISSQDPSSMLVHTSRGLFSAKSKIQLRHFALG
CCCHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCHHHEECCCCHHHHHHHHHHHHHHHH
WFAYFICLYVDYHQFKRWAWVLYALILFSLIGLFFVPAVQNVHRWYRIPIINLSVQPSEY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCHHH
AKLVVVIMLSYMLEMRKARISSKTTAFIACIIVGIPFLLILKEPDLGTALVLCPIALTIF
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHH
YIGNIYPPLVKICSIFAALGMLCSLLIFSGIIPHDTVKPYALRVLKEYQYERLSPSNHHQ
HHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHH
RASLISIGVGGLKGQGWKSGEFAGRGWLPYGYTDSVFPAIGEEFGLLGLLFVLWLFYNLV
HHHHHEECCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
CFGCRTVAVAVDDFGRFLAGGVTVHLVMHVLINVSMMSGLLPITGVPLVLISYGGSSVIS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHH
TMASLGILQSIYSRRFAKY
HHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]