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Identifier: 15834713

GI number: 15834713

Start: 106848

End: 108215

Strand: Reverse

Name: Not Available

Synonym: TC0088

Alternate gene names: NA

Gene position: 108215-106848 (Counterclockwise)

Preceding gene: 15834714

Following gene: 15834712

Centisome position: 10.09

GC content: 41.74

Gene sequence:

>1368_bases
ATGACCGATTCTTCCTATGTAGACTTATCATGTTTATTGGATAAGCTTCTTCCGATTCGACAAGAGCATTTACTAGACTA
CTGGCCCTCTCTCTCCCTTCAACAAAAGCGATGCTTAGGGAGACAAATATCTCAAATCAATATTCCCTTTTTCTTTCGCC
AGCAGGAATTATTACAAGCATCGCCCTATTCCCATCCCTCATACACCCCCCTATCGCCTACATACTATGCGGGGGAGACT
CCGGATTATGCTCAACTAGGATTACAACTTTCTCAAGCAGGGAAAGTAGGCTGTATCGTATTAGCTGGAGGACAAGGATC
TCGCTTAAAATTTGATGGACCAAAAGGTCTCTATCCCGTCTCTTCCGTAAAGAAAAAACCTTTGTACCAACTTGTTGCAG
AGAAAGTAGTGGCAGCTAGTAAACTAGTAGGAAGGCCTTTACCTGTAGCATTCATGACTTCCCCACTCAACCATCAACAA
ACCCTGTCCTACTTTACTGCTAATCGCTATTTTAATTTGGATCCCTCTCAAGTGGATTTCTTTTGCCAACCCCTTTGGCC
TCTTTTATCCCTATCCGGAGACCTTTTCCTAGAATCAGTAGATAGCTTAGCACTGGGTCCTACCGGTAATGGTTGTGTAG
CTTCTCTACTCAAATCTTCAGGCATTTGGGATAAATGGCATCAAGCGGGAATTGATATGGTTAGCGTGATCCCTATAGAT
AATCCTTTAGCCTTACCATTTGATAGAGAATTATTTGGGTTTCATGCAGCAGAACATAATGATGTAACAATTAAAACCAC
CTTACGCCAAAATGCAAAAGAAGATGTTGGCGTTCTTGTTGAGTTAGCAGAAAAAAAAATCTCAGTCGTTGAGTATTCAG
CTCTTCCAGATAAAGAACGCTTTGCCGTCACTTCGACTGGAGACCTCACTTATAAACTCGCTAACATTGGTCTGTACTGT
TTATCCATGGACTTTTTAGCCCAGACGGCACAGAAACCTCTACCTATCTATAAAGCGAATAAGCATGCCAAGCAATTATA
CCCCTCTCTAATTGAAAAAAATGCTTGGAAGTTTGAAGAATTTATTTTTGATCTATTTCGTTACAGTAATCGAAGTCAAG
CCATTGTGTACCCCCGGTACGAGTGCTTTGCCCCCCTTAAAAACTATGAAGGGAACCACAGCCCCGCGACCGTTCGTGAA
GCAATGCGCAAACGAGAGCAAGCTCTATTTACTGCAGTTACAGAAAGAAAGCTTTCCCCAAATACAATATTTGAATTAGA
AGCGGACTTTTATTACCCTTCCTCCCATACTTCCTTAGAGTGGGAAAACAAAATATTTTTCCAGGAACCAATTATTGAGG
CCTCATGA

Upstream 100 bases:

>100_bases
GCCGCTATACAAAAACAAATAGATCAGAGAAAAATTATCGAAAAGATCCACACTAATAAATATTCTAACAAAGAGCGCGA
ATAACTTAAGGCCGCCTATA

Downstream 100 bases:

>100_bases
AAGAGACTATAGCCTACCTTGGAATGGGCATGTGGGGATTTTCTTTAGCCAACCTTTTGGCTAACAATGGACATCGCGTA
GTGGGATGGGCAAGGAATCC

Product: UDP-N-acetylglucosamine pyrophosphorylase, putative

Products: diphosphate; UDP-N-acetyl-D-glucosamine

Alternate protein names: NA

Number of amino acids: Translated: 455; Mature: 454

Protein sequence:

>455_residues
MTDSSYVDLSCLLDKLLPIRQEHLLDYWPSLSLQQKRCLGRQISQINIPFFFRQQELLQASPYSHPSYTPLSPTYYAGET
PDYAQLGLQLSQAGKVGCIVLAGGQGSRLKFDGPKGLYPVSSVKKKPLYQLVAEKVVAASKLVGRPLPVAFMTSPLNHQQ
TLSYFTANRYFNLDPSQVDFFCQPLWPLLSLSGDLFLESVDSLALGPTGNGCVASLLKSSGIWDKWHQAGIDMVSVIPID
NPLALPFDRELFGFHAAEHNDVTIKTTLRQNAKEDVGVLVELAEKKISVVEYSALPDKERFAVTSTGDLTYKLANIGLYC
LSMDFLAQTAQKPLPIYKANKHAKQLYPSLIEKNAWKFEEFIFDLFRYSNRSQAIVYPRYECFAPLKNYEGNHSPATVRE
AMRKREQALFTAVTERKLSPNTIFELEADFYYPSSHTSLEWENKIFFQEPIIEAS

Sequences:

>Translated_455_residues
MTDSSYVDLSCLLDKLLPIRQEHLLDYWPSLSLQQKRCLGRQISQINIPFFFRQQELLQASPYSHPSYTPLSPTYYAGET
PDYAQLGLQLSQAGKVGCIVLAGGQGSRLKFDGPKGLYPVSSVKKKPLYQLVAEKVVAASKLVGRPLPVAFMTSPLNHQQ
TLSYFTANRYFNLDPSQVDFFCQPLWPLLSLSGDLFLESVDSLALGPTGNGCVASLLKSSGIWDKWHQAGIDMVSVIPID
NPLALPFDRELFGFHAAEHNDVTIKTTLRQNAKEDVGVLVELAEKKISVVEYSALPDKERFAVTSTGDLTYKLANIGLYC
LSMDFLAQTAQKPLPIYKANKHAKQLYPSLIEKNAWKFEEFIFDLFRYSNRSQAIVYPRYECFAPLKNYEGNHSPATVRE
AMRKREQALFTAVTERKLSPNTIFELEADFYYPSSHTSLEWENKIFFQEPIIEAS
>Mature_454_residues
TDSSYVDLSCLLDKLLPIRQEHLLDYWPSLSLQQKRCLGRQISQINIPFFFRQQELLQASPYSHPSYTPLSPTYYAGETP
DYAQLGLQLSQAGKVGCIVLAGGQGSRLKFDGPKGLYPVSSVKKKPLYQLVAEKVVAASKLVGRPLPVAFMTSPLNHQQT
LSYFTANRYFNLDPSQVDFFCQPLWPLLSLSGDLFLESVDSLALGPTGNGCVASLLKSSGIWDKWHQAGIDMVSVIPIDN
PLALPFDRELFGFHAAEHNDVTIKTTLRQNAKEDVGVLVELAEKKISVVEYSALPDKERFAVTSTGDLTYKLANIGLYCL
SMDFLAQTAQKPLPIYKANKHAKQLYPSLIEKNAWKFEEFIFDLFRYSNRSQAIVYPRYECFAPLKNYEGNHSPATVREA
MRKREQALFTAVTERKLSPNTIFELEADFYYPSSHTSLEWENKIFFQEPIIEAS

Specific function: Unknown

COG id: COG4284

COG function: function code G; UDP-glucose pyrophosphorylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDPGP type 1 family [H]

Homologues:

Organism=Homo sapiens, GI156627575, Length=418, Percent_Identity=30.1435406698565, Blast_Score=154, Evalue=1e-37,
Organism=Homo sapiens, GI187936958, Length=337, Percent_Identity=31.4540059347181, Blast_Score=154, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI17552518, Length=399, Percent_Identity=27.3182957393484, Blast_Score=95, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI193206427, Length=307, Percent_Identity=28.0130293159609, Blast_Score=81, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6320100, Length=476, Percent_Identity=27.9411764705882, Blast_Score=142, Evalue=1e-34,
Organism=Drosophila melanogaster, GI19920822, Length=437, Percent_Identity=29.9771167048055, Blast_Score=168, Evalue=6e-42,
Organism=Drosophila melanogaster, GI24582229, Length=432, Percent_Identity=30.0925925925926, Blast_Score=167, Evalue=1e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002618 [H]

Pfam domain/function: PF01704 UDPGP [H]

EC number: 2.7.7.23

Molecular weight: Translated: 51356; Mature: 51225

Theoretical pI: Translated: 6.99; Mature: 6.99

Prosite motif: PS00663 VINCULIN_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDSSYVDLSCLLDKLLPIRQEHLLDYWPSLSLQQKRCLGRQISQINIPFFFRQQELLQA
CCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCEEECHHHHHHC
SPYSHPSYTPLSPTYYAGETPDYAQLGLQLSQAGKVGCIVLAGGQGSRLKFDGPKGLYPV
CCCCCCCCCCCCCCEECCCCCCHHHHCCCHHCCCCEEEEEEECCCCCEEEECCCCCCCCH
SSVKKKPLYQLVAEKVVAASKLVGRPLPVAFMTSPLNHQQTLSYFTANRYFNLDPSQVDF
HHHCCCHHHHHHHHHHHHHHHHHCCCCCHHEECCCCCHHHHHHHHHCCCEECCCCHHHHH
FCQPLWPLLSLSGDLFLESVDSLALGPTGNGCVASLLKSSGIWDKWHQAGIDMVSVIPID
HHHHHHHHHHCCCHHHHHHHHHEECCCCCCHHHHHHHHHCCCCHHHHHCCCCEEEEEECC
NPLALPFDRELFGFHAAEHNDVTIKTTLRQNAKEDVGVLVELAEKKISVVEYSALPDKER
CCCCCCCCHHHHHEECCCCCCEEEEEHHHHCCHHHHHHHHHHHHHHHEEEEECCCCCCCC
FAVTSTGDLTYKLANIGLYCLSMDFLAQTAQKPLPIYKANKHAKQLYPSLIEKNAWKFEE
EEEEECCCEEEEHHHHCCCEEHHHHHHHHHCCCCCCEECCHHHHHHHHHHHHCCCHHHHH
FIFDLFRYSNRSQAIVYPRYECFAPLKNYEGNHSPATVREAMRKREQALFTAVTERKLSP
HHHHHHHCCCCCCEEEECCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
NTIFELEADFYYPSSHTSLEWENKIFFQEPIIEAS
CEEEEEEECEECCCCCCCCCCCCEEEEECCCCCCC
>Mature Secondary Structure 
TDSSYVDLSCLLDKLLPIRQEHLLDYWPSLSLQQKRCLGRQISQINIPFFFRQQELLQA
CCCCEEEHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCEEECHHHHHHC
SPYSHPSYTPLSPTYYAGETPDYAQLGLQLSQAGKVGCIVLAGGQGSRLKFDGPKGLYPV
CCCCCCCCCCCCCCEECCCCCCHHHHCCCHHCCCCEEEEEEECCCCCEEEECCCCCCCCH
SSVKKKPLYQLVAEKVVAASKLVGRPLPVAFMTSPLNHQQTLSYFTANRYFNLDPSQVDF
HHHCCCHHHHHHHHHHHHHHHHHCCCCCHHEECCCCCHHHHHHHHHCCCEECCCCHHHHH
FCQPLWPLLSLSGDLFLESVDSLALGPTGNGCVASLLKSSGIWDKWHQAGIDMVSVIPID
HHHHHHHHHHCCCHHHHHHHHHEECCCCCCHHHHHHHHHCCCCHHHHHCCCCEEEEEECC
NPLALPFDRELFGFHAAEHNDVTIKTTLRQNAKEDVGVLVELAEKKISVVEYSALPDKER
CCCCCCCCHHHHHEECCCCCCEEEEEHHHHCCHHHHHHHHHHHHHHHEEEEECCCCCCCC
FAVTSTGDLTYKLANIGLYCLSMDFLAQTAQKPLPIYKANKHAKQLYPSLIEKNAWKFEE
EEEEECCCEEEEHHHHCCCEEHHHHHHHHHCCCCCCEECCHHHHHHHHHHHHCCCHHHHH
FIFDLFRYSNRSQAIVYPRYECFAPLKNYEGNHSPATVREAMRKREQALFTAVTERKLSP
HHHHHHHCCCCCCEEEECCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
NTIFELEADFYYPSSHTSLEWENKIFFQEPIIEAS
CEEEEEEECEECCCCCCCCCCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: UTP; N-acetyl-alpha-D-glucosamine 1-phosphate

Specific reaction: UTP + N-acetyl-alpha-D-glucosamine 1-phosphate = diphosphate + UDP-N-acetyl-D-glucosamine

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA