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The map label for this gene is engA

Identifier: 15834701

GI number: 15834701

Start: 88050

End: 89522

Strand: Reverse

Name: engA

Synonym: TC0076

Alternate gene names: 15834701

Gene position: 89522-88050 (Counterclockwise)

Preceding gene: 15834702

Following gene: 15834700

Centisome position: 8.34

GC content: 39.99

Gene sequence:

>1473_bases
ATGCGTATTGCTATTTTAGGAAGACCAAATGTAGGGAAGTCTTCTATTTTTAACCGCTTATGCAAACGTTCTTTAGCGAT
TGTCAATGCTCAAGAAGGAACTACGCGAGATCGTTTGTATGGAGAAATTCGAGCTTGGGATTCTATTGTCCATGTTATCG
ACACAGGAGGGGTAGACCAAGAGTCTACAGACCGATTCCAGAAGCAGATTCATAAACAAGCGTTAGCTGCCGCAGAAGAG
GCTTCTGTTCTTTTGCTTGTTGTAGATATCCGATGTGGGATCACTAAACAAGATGAAGAGCTTGCAAAACGTCTTCTTCC
TCTAAAAAAACCATTAATTCTCGTCATGAATAAAGCGGATTCTCAACAGGACCTCCAGCGCATTCATGAATTCTATGGAT
TGGGCATCTCTAATATGATTGCTACATCCGCTAGCCACGACAAGCATATTGATGTGCTGTTAGAACGCATTCGTCAGGTA
GCGGAAATTCCTCTTCCATCTGCAGAAGAACAAGAAAATACACAAGAAGAAGAGTTCTCCTCTAAGGAATCTTCTGTAGC
CCTACATACTTTCGCAGATGAAACTCTTTTTGAAAATGAATCTTTATCTCAAGAAGAAGCTTCTTTCTTGGAAGAACTTG
TTGCACAAACAACAACACCATCTATCTCAAATCGTCCACTGAAAGTGGCTCTCATTGGACATCCCAATGTTGGAAAATCC
TCCATTGTTAATGCGCTTCTTAAAGAAGAGCGCTGTATAACAGATAACTCTCCTGGAACTACACGAGACAATGTAGATGT
CTCCTATACGTATAACGATAAAGAATACGTCTTCATAGATACTGCGGGACTACGAAAAGCCAAGAGCATTAAAAATTCTG
TAGAATGGATGTCCTCCTCACGAACAGAGAAGGCGATTTCCCGAGCAGATATTTGCCTATTAGTGATAGATGCTACGCAG
CAACTCTCTTATCAAGATAAACGCATTTTATCCCTGATTGCGAGATATAAAAAACCTCATGTTATTCTCGTTAATAAATG
GGACCTAATGTTTGGGGTTCGGATGGAACACTACGTCCAGGATTTGCGAAAAATGGATCCCTATATAGGCCAAGCTCGAA
TACTTTGTATTTCAGCAAAACAGCGCCGTAACCTTTCACAAATCTTCTCTGCTGTAGATGATGTCTACACCATTGCAACG
ACAAAACTATCGACTTCCCTAGTTAATAAGGTGCTAGCGGGTGCTATGCAAAGACATCACCCTCAAGTGATTAATGGTAA
ACGTCTACGCATTTACTATGCGATTCACAAAACGGTAACGCCATTCTCCTTCTTGCTCTTTATTAATTCCAATACGCTGC
TCACCAAGCCTTACGAACTGTATTTAAAAAATACTCTAAAAGCAGCTTTTAATTTATATGGAATACCTTTTGATTTAGAA
TACAAAGCAAAACCTGCGAGAAAATCAAATTAA

Upstream 100 bases:

>100_bases
AAGGCTCTCTTAAATAGTTAATTTTATTTCTTTAGATTTAATTTTTTACTCCTTATCATTTCTTCCTAATTATTCAATTC
TGGATTAATAGAGCCTGTTT

Downstream 100 bases:

>100_bases
TTTGTAAAAAAATAAAAATCTTTTATTAGAAATAATAAAAAATAAAATAGTTATTTCTTGGAGATTTTAATCCCTATGCA
CTACGAACTATACGATGAAT

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA

Number of amino acids: Translated: 490; Mature: 490

Protein sequence:

>490_residues
MRIAILGRPNVGKSSIFNRLCKRSLAIVNAQEGTTRDRLYGEIRAWDSIVHVIDTGGVDQESTDRFQKQIHKQALAAAEE
ASVLLLVVDIRCGITKQDEELAKRLLPLKKPLILVMNKADSQQDLQRIHEFYGLGISNMIATSASHDKHIDVLLERIRQV
AEIPLPSAEEQENTQEEEFSSKESSVALHTFADETLFENESLSQEEASFLEELVAQTTTPSISNRPLKVALIGHPNVGKS
SIVNALLKEERCITDNSPGTTRDNVDVSYTYNDKEYVFIDTAGLRKAKSIKNSVEWMSSSRTEKAISRADICLLVIDATQ
QLSYQDKRILSLIARYKKPHVILVNKWDLMFGVRMEHYVQDLRKMDPYIGQARILCISAKQRRNLSQIFSAVDDVYTIAT
TKLSTSLVNKVLAGAMQRHHPQVINGKRLRIYYAIHKTVTPFSFLLFINSNTLLTKPYELYLKNTLKAAFNLYGIPFDLE
YKAKPARKSN

Sequences:

>Translated_490_residues
MRIAILGRPNVGKSSIFNRLCKRSLAIVNAQEGTTRDRLYGEIRAWDSIVHVIDTGGVDQESTDRFQKQIHKQALAAAEE
ASVLLLVVDIRCGITKQDEELAKRLLPLKKPLILVMNKADSQQDLQRIHEFYGLGISNMIATSASHDKHIDVLLERIRQV
AEIPLPSAEEQENTQEEEFSSKESSVALHTFADETLFENESLSQEEASFLEELVAQTTTPSISNRPLKVALIGHPNVGKS
SIVNALLKEERCITDNSPGTTRDNVDVSYTYNDKEYVFIDTAGLRKAKSIKNSVEWMSSSRTEKAISRADICLLVIDATQ
QLSYQDKRILSLIARYKKPHVILVNKWDLMFGVRMEHYVQDLRKMDPYIGQARILCISAKQRRNLSQIFSAVDDVYTIAT
TKLSTSLVNKVLAGAMQRHHPQVINGKRLRIYYAIHKTVTPFSFLLFINSNTLLTKPYELYLKNTLKAAFNLYGIPFDLE
YKAKPARKSN
>Mature_490_residues
MRIAILGRPNVGKSSIFNRLCKRSLAIVNAQEGTTRDRLYGEIRAWDSIVHVIDTGGVDQESTDRFQKQIHKQALAAAEE
ASVLLLVVDIRCGITKQDEELAKRLLPLKKPLILVMNKADSQQDLQRIHEFYGLGISNMIATSASHDKHIDVLLERIRQV
AEIPLPSAEEQENTQEEEFSSKESSVALHTFADETLFENESLSQEEASFLEELVAQTTTPSISNRPLKVALIGHPNVGKS
SIVNALLKEERCITDNSPGTTRDNVDVSYTYNDKEYVFIDTAGLRKAKSIKNSVEWMSSSRTEKAISRADICLLVIDATQ
QLSYQDKRILSLIARYKKPHVILVNKWDLMFGVRMEHYVQDLRKMDPYIGQARILCISAKQRRNLSQIFSAVDDVYTIAT
TKLSTSLVNKVLAGAMQRHHPQVINGKRLRIYYAIHKTVTPFSFLLFINSNTLLTKPYELYLKNTLKAAFNLYGIPFDLE
YKAKPARKSN

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain

Homologues:

Organism=Escherichia coli, GI87082120, Length=486, Percent_Identity=33.9506172839506, Blast_Score=263, Evalue=2e-71,
Organism=Escherichia coli, GI2367268, Length=162, Percent_Identity=33.9506172839506, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1788919, Length=124, Percent_Identity=33.0645161290323, Blast_Score=63, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17532761, Length=137, Percent_Identity=28.4671532846715, Blast_Score=66, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6323665, Length=204, Percent_Identity=30.8823529411765, Blast_Score=87, Evalue=8e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DER_CHLMU (Q9PLM3)

Other databases:

- EMBL:   AE002160
- PIR:   A81744
- RefSeq:   NP_296460.1
- ProteinModelPortal:   Q9PLM3
- SMR:   Q9PLM3
- GeneID:   1245605
- GenomeReviews:   AE002160_GR
- KEGG:   cmu:TC0076
- TIGR:   TC_0076
- HOGENOM:   HBG592135
- OMA:   TRDRTYQ
- ProtClustDB:   PRK00093
- BioCyc:   CMUR243161:TC_0076-MONOMER
- GO:   GO:0005622
- HAMAP:   MF_00195
- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225
- Gene3D:   G3DSA:3.30.300.20
- PIRSF:   PIRSF006485
- PRINTS:   PR00326
- TIGRFAMs:   TIGR03594
- TIGRFAMs:   TIGR00231

Pfam domain/function: PF01926 MMR_HSR1

EC number: NA

Molecular weight: Translated: 55440; Mature: 55440

Theoretical pI: Translated: 9.12; Mature: 9.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIAILGRPNVGKSSIFNRLCKRSLAIVNAQEGTTRDRLYGEIRAWDSIVHVIDTGGVDQ
CEEEEECCCCCCHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCC
ESTDRFQKQIHKQALAAAEEASVLLLVVDIRCGITKQDEELAKRLLPLKKPLILVMNKAD
HHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCHHHHHHHHCCCCCCEEEEEECCC
SQQDLQRIHEFYGLGISNMIATSASHDKHIDVLLERIRQVAEIPLPSAEEQENTQEEEFS
CHHHHHHHHHHHCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHCCHHHHHC
SKESSVALHTFADETLFENESLSQEEASFLEELVAQTTTPSISNRPLKVALIGHPNVGKS
CCCCCEEEEEECCHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCHH
SIVNALLKEERCITDNSPGTTRDNVDVSYTYNDKEYVFIDTAGLRKAKSIKNSVEWMSSS
HHHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCEEEEEECCCCHHHHHHHHHHHHHHCC
RTEKAISRADICLLVIDATQQLSYQDKRILSLIARYKKPHVILVNKWDLMFGVRMEHYVQ
HHHHHHHHCCEEEEEEECHHHCCHHHHHHHHHHHHHCCCCEEEEECCCHHEHHHHHHHHH
DLRKMDPYIGQARILCISAKQRRNLSQIFSAVDDVYTIATTKLSTSLVNKVLAGAMQRHH
HHHHHCCCCCCEEEEEEECHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PQVINGKRLRIYYAIHKTVTPFSFLLFINSNTLLTKPYELYLKNTLKAAFNLYGIPFDLE
CCCCCCCEEEEEEEEECCCCCEEEEEEEECCEEEECHHHHHHHHHHHHHHHHCCCCEEEC
YKAKPARKSN
CCCCCCCCCC
>Mature Secondary Structure
MRIAILGRPNVGKSSIFNRLCKRSLAIVNAQEGTTRDRLYGEIRAWDSIVHVIDTGGVDQ
CEEEEECCCCCCHHHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCC
ESTDRFQKQIHKQALAAAEEASVLLLVVDIRCGITKQDEELAKRLLPLKKPLILVMNKAD
HHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCHHHHHHHHCCCCCCEEEEEECCC
SQQDLQRIHEFYGLGISNMIATSASHDKHIDVLLERIRQVAEIPLPSAEEQENTQEEEFS
CHHHHHHHHHHHCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHCCHHHHHC
SKESSVALHTFADETLFENESLSQEEASFLEELVAQTTTPSISNRPLKVALIGHPNVGKS
CCCCCEEEEEECCHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCHH
SIVNALLKEERCITDNSPGTTRDNVDVSYTYNDKEYVFIDTAGLRKAKSIKNSVEWMSSS
HHHHHHHHHCCCCCCCCCCCCCCCEEEEEEECCCEEEEEECCCCHHHHHHHHHHHHHHCC
RTEKAISRADICLLVIDATQQLSYQDKRILSLIARYKKPHVILVNKWDLMFGVRMEHYVQ
HHHHHHHHCCEEEEEEECHHHCCHHHHHHHHHHHHHCCCCEEEEECCCHHEHHHHHHHHH
DLRKMDPYIGQARILCISAKQRRNLSQIFSAVDDVYTIATTKLSTSLVNKVLAGAMQRHH
HHHHHCCCCCCEEEEEEECHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PQVINGKRLRIYYAIHKTVTPFSFLLFINSNTLLTKPYELYLKNTLKAAFNLYGIPFDLE
CCCCCCCEEEEEEEEECCCCCEEEEEEEECCEEEECHHHHHHHHHHHHHHHHCCCCEEEC
YKAKPARKSN
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10684935