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Identifier: 15834646

GI number: 15834646

Start: 28506

End: 29999

Strand: Direct

Name: Not Available

Synonym: TC0021

Alternate gene names: 15834646

Gene position: 28506-29999 (Clockwise)

Preceding gene: 15834645

Following gene: 15834647

Centisome position: 2.66

GC content: 40.56

Gene sequence:

>1494_bases
GTGAATGAAACTTTACACGTACAAAATATTCTCCAATCTCTATTAGCTCAACACATTCTCCTTCCTTTTGATCTAGTTTT
CGCTCAGAAGCACTTGGCTCAGACATCTTCTTCCAATCGAGAGGCCGAGGCTTTTTTAGTTGTAGCGTCAGCACTGTTGC
GTTGCGGCTATCCTTATTTTACTATCCATAAAGCAACAATAAGCCCTACGCTTCCAGGAATTTCAAATAGGCTATTATTC
CAATGGTTCCAGGCATTGCCTTCTGATGTGAAAGCGACACTTTTTGAAGTGTGTGATGATAAAATTTATCTACGCTCATT
GTTTCTTTTGAGAGAAAAAGTCTTTCAAAAACTGCATACACTAGCAGAAGCGGTTCCAAGAACTTCTTTAATTTTTGAAA
ATGTTTCTCAGCTGTCGGAAGAACAGAACGCAGTGTTAGGAAATGTATTAAATTCTTGTTTTTCTCTTGTTTGCGGTGGA
CCTGGAACAGGAAAAACATTTTTAGCTGTGCAGATGATTCGATTGATACTTTCACAAATCCCTTCAGCACAGATTGTGGT
GGCATCCCCAACAGGGAAAGCAGCGGCTCATTTGCACAGTGTATTATCTTCTCAGGAGATTATAGGCGCTTCCGTAGAAG
TAGTTACCATTCATAAATTTTTGAAAGATGTGAATAACGGACGTTCCCCAGTAGACTTACTTCTAATAGATGAAGGATCT
ATGGTTACTATGAATCTTCTACATGGACTGATAAAAACTATACGGGGGGAGATTCGAGAAGGGAAGTTATTTGCTGATAG
AATGGTCATTTTTGGAGATGTGAATCAGCTTCCTCCTATAGGCATTGGAGTTGGGAATCCTTTTCATGAATTGGTATCGG
AATTTACTCAACAGGCATTCTTCTTATCTACTAGTCATCGAGCTAAGCACAAGGAGTTGCAGGAGTTGGCAAAATCCGTT
CTTCATAAACAGCCTATTCCATTTCAGCCATTACCTTCCCGCAAGGAGGCTATCCGCAGGTTATCTGATGCTTTTGTACA
AACTGCTAAAGCAGGAATATCCTTGTGTGCCTTGACTCCAATGCGGCAGGGGCCTTGGGGGTTTTTACAGTTGAACCGGC
TATTGTTTAATGAGATGCAAGAGAAGCATCCTCAGGCTCCTGTTCCTATTATAGTGACAGAAAGATATGAAACCTGGGGA
CTAACAAACGGAGATACTGGAATTTTAGATCCTTTAACGCAACAGCTGCATTTCATGAATGGAGAGATTCTGCGTAAGGA
AGATTTCCCTTATTATTCCTACAATTATGTCATGTCGGTGCATAAAAGCCAGGGTAGCGAATACGATCGTGTGATTGTTA
TTCTTCCGAAAGGAAGCGAAGTTTTTGATTCTGCTATTCTTTATACTGCTATCACGAGGACGAAGCAATGTGTGGAGATT
TGGGCGGATAAAGAGACTTTAGATATGGTGATTTCGAAAAAAGGTCGTTACTAA

Upstream 100 bases:

>100_bases
AAGCTTCCTTTAGGTAAGGATACTTGTGATTCCCAAGTGCAGAAGGCTTTGCTTTTGTGCCATAAATATATAACACGACA
ACAAAAAAATACTTTCTTCC

Downstream 100 bases:

>100_bases
TTAGAACTGGCACACTTTTTGCTCCTAGTATGAATGAATGATTTCAGAAAGAAGGAGTGGATGTAATGGATCAATTATCG
CAGATGCACCAAGAGCTAGC

Product: exodeoxyribonuclease V, alpha subunit, putative

Products: NA

Alternate protein names: Exodeoxyribonuclease V 67 kDa polypeptide [H]

Number of amino acids: Translated: 497; Mature: 497

Protein sequence:

>497_residues
MNETLHVQNILQSLLAQHILLPFDLVFAQKHLAQTSSSNREAEAFLVVASALLRCGYPYFTIHKATISPTLPGISNRLLF
QWFQALPSDVKATLFEVCDDKIYLRSLFLLREKVFQKLHTLAEAVPRTSLIFENVSQLSEEQNAVLGNVLNSCFSLVCGG
PGTGKTFLAVQMIRLILSQIPSAQIVVASPTGKAAAHLHSVLSSQEIIGASVEVVTIHKFLKDVNNGRSPVDLLLIDEGS
MVTMNLLHGLIKTIRGEIREGKLFADRMVIFGDVNQLPPIGIGVGNPFHELVSEFTQQAFFLSTSHRAKHKELQELAKSV
LHKQPIPFQPLPSRKEAIRRLSDAFVQTAKAGISLCALTPMRQGPWGFLQLNRLLFNEMQEKHPQAPVPIIVTERYETWG
LTNGDTGILDPLTQQLHFMNGEILRKEDFPYYSYNYVMSVHKSQGSEYDRVIVILPKGSEVFDSAILYTAITRTKQCVEI
WADKETLDMVISKKGRY

Sequences:

>Translated_497_residues
MNETLHVQNILQSLLAQHILLPFDLVFAQKHLAQTSSSNREAEAFLVVASALLRCGYPYFTIHKATISPTLPGISNRLLF
QWFQALPSDVKATLFEVCDDKIYLRSLFLLREKVFQKLHTLAEAVPRTSLIFENVSQLSEEQNAVLGNVLNSCFSLVCGG
PGTGKTFLAVQMIRLILSQIPSAQIVVASPTGKAAAHLHSVLSSQEIIGASVEVVTIHKFLKDVNNGRSPVDLLLIDEGS
MVTMNLLHGLIKTIRGEIREGKLFADRMVIFGDVNQLPPIGIGVGNPFHELVSEFTQQAFFLSTSHRAKHKELQELAKSV
LHKQPIPFQPLPSRKEAIRRLSDAFVQTAKAGISLCALTPMRQGPWGFLQLNRLLFNEMQEKHPQAPVPIIVTERYETWG
LTNGDTGILDPLTQQLHFMNGEILRKEDFPYYSYNYVMSVHKSQGSEYDRVIVILPKGSEVFDSAILYTAITRTKQCVEI
WADKETLDMVISKKGRY
>Mature_497_residues
MNETLHVQNILQSLLAQHILLPFDLVFAQKHLAQTSSSNREAEAFLVVASALLRCGYPYFTIHKATISPTLPGISNRLLF
QWFQALPSDVKATLFEVCDDKIYLRSLFLLREKVFQKLHTLAEAVPRTSLIFENVSQLSEEQNAVLGNVLNSCFSLVCGG
PGTGKTFLAVQMIRLILSQIPSAQIVVASPTGKAAAHLHSVLSSQEIIGASVEVVTIHKFLKDVNNGRSPVDLLLIDEGS
MVTMNLLHGLIKTIRGEIREGKLFADRMVIFGDVNQLPPIGIGVGNPFHELVSEFTQQAFFLSTSHRAKHKELQELAKSV
LHKQPIPFQPLPSRKEAIRRLSDAFVQTAKAGISLCALTPMRQGPWGFLQLNRLLFNEMQEKHPQAPVPIIVTERYETWG
LTNGDTGILDPLTQQLHFMNGEILRKEDFPYYSYNYVMSVHKSQGSEYDRVIVILPKGSEVFDSAILYTAITRTKQCVEI
WADKETLDMVISKKGRY

Specific function: Exhibits several catalytic activities, including ATP- dependent exonuclease, ATP-stimulated endonuclease, ATP-dependent unwinding and DNA-dependent ATPase activities. Strand cleavage occurs 5' to 3' during the unwinding of duplex DNA at CHI sequences, whi

COG id: COG0507

COG function: function code L; ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the recD family [H]

Homologues:

Organism=Escherichia coli, GI1789182, Length=156, Percent_Identity=32.0512820512821, Blast_Score=75, Evalue=9e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR007807
- InterPro:   IPR006344
- InterPro:   IPR000606 [H]

Pfam domain/function: PF05127 DUF699; PF01443 Viral_helicase1 [H]

EC number: =3.1.11.5 [H]

Molecular weight: Translated: 55603; Mature: 55603

Theoretical pI: Translated: 8.16; Mature: 8.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNETLHVQNILQSLLAQHILLPFDLVFAQKHLAQTSSSNREAEAFLVVASALLRCGYPYF
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCEE
TIHKATISPTLPGISNRLLFQWFQALPSDVKATLFEVCDDKIYLRSLFLLREKVFQKLHT
EEEEEECCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
LAEAVPRTSLIFENVSQLSEEQNAVLGNVLNSCFSLVCGGPGTGKTFLAVQMIRLILSQI
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHC
PSAQIVVASPTGKAAAHLHSVLSSQEIIGASVEVVTIHKFLKDVNNGRSPVDLLLIDEGS
CCCEEEEECCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCEEEEEECCCC
MVTMNLLHGLIKTIRGEIREGKLFADRMVIFGDVNQLPPIGIGVGNPFHELVSEFTQQAF
CHHHHHHHHHHHHHHHHHHCCCEEHHHEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHH
FLSTSHRAKHKELQELAKSVLHKQPIPFQPLPSRKEAIRRLSDAFVQTAKAGISLCALTP
HHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEECC
MRQGPWGFLQLNRLLFNEMQEKHPQAPVPIIVTERYETWGLTNGDTGILDPLTQQLHFMN
CCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEECCHHHCCCCCCCCCCHHHHHHHHHHCC
GEILRKEDFPYYSYNYVMSVHKSQGSEYDRVIVILPKGSEVFDSAILYTAITRTKQCVEI
CCEEECCCCCCEEEHHHEEEECCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHH
WADKETLDMVISKKGRY
HCCHHHHHHHHHCCCCC
>Mature Secondary Structure
MNETLHVQNILQSLLAQHILLPFDLVFAQKHLAQTSSSNREAEAFLVVASALLRCGYPYF
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCEE
TIHKATISPTLPGISNRLLFQWFQALPSDVKATLFEVCDDKIYLRSLFLLREKVFQKLHT
EEEEEECCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
LAEAVPRTSLIFENVSQLSEEQNAVLGNVLNSCFSLVCGGPGTGKTFLAVQMIRLILSQI
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHC
PSAQIVVASPTGKAAAHLHSVLSSQEIIGASVEVVTIHKFLKDVNNGRSPVDLLLIDEGS
CCCEEEEECCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCEEEEEECCCC
MVTMNLLHGLIKTIRGEIREGKLFADRMVIFGDVNQLPPIGIGVGNPFHELVSEFTQQAF
CHHHHHHHHHHHHHHHHHHCCCEEHHHEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHH
FLSTSHRAKHKELQELAKSVLHKQPIPFQPLPSRKEAIRRLSDAFVQTAKAGISLCALTP
HHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEECC
MRQGPWGFLQLNRLLFNEMQEKHPQAPVPIIVTERYETWGLTNGDTGILDPLTQQLHFMN
CCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEECCHHHCCCCCCCCCCHHHHHHHHHHCC
GEILRKEDFPYYSYNYVMSVHKSQGSEYDRVIVILPKGSEVFDSAILYTAITRTKQCVEI
CCEEECCCCCCEEEHHHEEEECCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHH
WADKETLDMVISKKGRY
HCCHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3537961; 9278503; 3537960 [H]