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Identifier: 15834630

GI number: 15834630

Start: 5599

End: 6801

Strand: Direct

Name: Not Available

Synonym: TC0005

Alternate gene names: 15834630

Gene position: 5599-6801 (Clockwise)

Preceding gene: 15834629

Following gene: 15834631

Centisome position: 0.52

GC content: 40.65

Gene sequence:

>1203_bases
GTGAGTCTTTTTGAACAGTTACCTTCTTTCTCTCCGGATTCTATTCTTGGTTTAGCACAAGCTTTTCAAGAAGATCCTCG
TGAGGATAAAATTAATTTATTACTGGGTACTTACGAGCGAGAAAAAAGCCGATACGGAGGATTCTCAAGCGTCAGAAAGG
CTCAAACAGTGTTTTTTGGTGATGAGAAAGATAAAAACTATCTTCCCATCAGAGGATCCTCAGTTTTTTTAGACCAGATG
GCTGCTCTATGTTTTGGCGAGATTGATGCTAATCGATGGACTGGAGTGCAAGCTGTTGGTGGGACTGGAGCCTTACATTT
GGGCGCCTTAGTGTATGCTAAATCTTCTCTTGCAGGTAAAGTCTATATCCCAGCTCAAACTTGGGGGAACCACTCTAGAA
TTTTTTCTCGTCTAGGATTGTCCCTAGAACATTATCCCTACTATGATCAAGAAAAAAAAGATCTCGATTTGCAAGGATTA
AAAGCATCTCTTCGGGATGCTCCTGAGGCTTCTTTAATTCTTTTACATTGTTGTTGTCATAACCCTACAGGGAAGGATAT
TCCCCTTTCTGAATGGCCTGAAATTATTGCTATTATAAAGGACAGAGGCCTCATTCCTTTCTTTGATATGGCTTATTTAG
GTTTTGCTAACGGAATAGTAGAGGATCGCCGACCTGTTCGGCTTTGCATAGAGGCTGGAGTTGCTACTTTTGTTGCAGGA
AGTTGTAGTAAAAACTTCTCATTATATGGTTCTCGGGTAGGATTTTTTGGGGTTGTTCACCAAGATAAAACGGATTTGAG
CAGGATACTTTCTTTCTTGGAAGAGCAGATCCGTGGGGAATACTCTTCTCCTGCTAGAGAAGGTGTTGCAATCGTTACCT
CTATATTAGAGAATCCCTACTTGCGACAAGAGTGGGGGCTTGAACTGAATGGTATTCGCCAGTCTTTGGAAGAAATTCGA
GCGAATTTTGTTATTGCAATGAGAGAAGTAGCGGGACATTCTTTTGATTTCATCGCGTCTCAGAAAGGATTTTTTGGGTA
TCCAGGTTTTTCAAAAGAGCAGGTTGTGTTCCTTAGAGAAGAGCTTGGTATTTATACAACAGCTGGTGGAAGATTCAATT
TAAATGGCATTACAGATAAAAATATAAATCGTGTTATCCACGGTTTTGCTAAGGCCTATGAATACTCTCGGTCCGTATCA
TAA

Upstream 100 bases:

>100_bases
AGACTAGGGTATCATGTTTGTACGATTTAGGACAATAAGCTGTGGTCTTATCAGAAAAAAAAGATAATAATCGGCAGATT
CATTATAGAGAGGTGTTATT

Downstream 100 bases:

>100_bases
ACGTATTCGGTTTATTACTTATCTCTTTGTCGCTTCAGGAATTATTGTAAGTTGGAATCTTCCTAGAAGCGTTTATGAGT
CGCTTCAGGATAAATTTGTA

Product: aromatic amino acid aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 400; Mature: 399

Protein sequence:

>400_residues
MSLFEQLPSFSPDSILGLAQAFQEDPREDKINLLLGTYEREKSRYGGFSSVRKAQTVFFGDEKDKNYLPIRGSSVFLDQM
AALCFGEIDANRWTGVQAVGGTGALHLGALVYAKSSLAGKVYIPAQTWGNHSRIFSRLGLSLEHYPYYDQEKKDLDLQGL
KASLRDAPEASLILLHCCCHNPTGKDIPLSEWPEIIAIIKDRGLIPFFDMAYLGFANGIVEDRRPVRLCIEAGVATFVAG
SCSKNFSLYGSRVGFFGVVHQDKTDLSRILSFLEEQIRGEYSSPAREGVAIVTSILENPYLRQEWGLELNGIRQSLEEIR
ANFVIAMREVAGHSFDFIASQKGFFGYPGFSKEQVVFLREELGIYTTAGGRFNLNGITDKNINRVIHGFAKAYEYSRSVS

Sequences:

>Translated_400_residues
MSLFEQLPSFSPDSILGLAQAFQEDPREDKINLLLGTYEREKSRYGGFSSVRKAQTVFFGDEKDKNYLPIRGSSVFLDQM
AALCFGEIDANRWTGVQAVGGTGALHLGALVYAKSSLAGKVYIPAQTWGNHSRIFSRLGLSLEHYPYYDQEKKDLDLQGL
KASLRDAPEASLILLHCCCHNPTGKDIPLSEWPEIIAIIKDRGLIPFFDMAYLGFANGIVEDRRPVRLCIEAGVATFVAG
SCSKNFSLYGSRVGFFGVVHQDKTDLSRILSFLEEQIRGEYSSPAREGVAIVTSILENPYLRQEWGLELNGIRQSLEEIR
ANFVIAMREVAGHSFDFIASQKGFFGYPGFSKEQVVFLREELGIYTTAGGRFNLNGITDKNINRVIHGFAKAYEYSRSVS
>Mature_399_residues
SLFEQLPSFSPDSILGLAQAFQEDPREDKINLLLGTYEREKSRYGGFSSVRKAQTVFFGDEKDKNYLPIRGSSVFLDQMA
ALCFGEIDANRWTGVQAVGGTGALHLGALVYAKSSLAGKVYIPAQTWGNHSRIFSRLGLSLEHYPYYDQEKKDLDLQGLK
ASLRDAPEASLILLHCCCHNPTGKDIPLSEWPEIIAIIKDRGLIPFFDMAYLGFANGIVEDRRPVRLCIEAGVATFVAGS
CSKNFSLYGSRVGFFGVVHQDKTDLSRILSFLEEQIRGEYSSPAREGVAIVTSILENPYLRQEWGLELNGIRQSLEEIRA
NFVIAMREVAGHSFDFIASQKGFFGYPGFSKEQVVFLREELGIYTTAGGRFNLNGITDKNINRVIHGFAKAYEYSRSVS

Specific function: Unknown

COG id: COG1448

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI73486658, Length=385, Percent_Identity=37.4025974025974, Blast_Score=252, Evalue=4e-67,
Organism=Homo sapiens, GI4504067, Length=404, Percent_Identity=34.9009900990099, Blast_Score=239, Evalue=3e-63,
Organism=Homo sapiens, GI117414139, Length=349, Percent_Identity=29.512893982808, Blast_Score=140, Evalue=3e-33,
Organism=Escherichia coli, GI1787159, Length=385, Percent_Identity=38.961038961039, Blast_Score=275, Evalue=4e-75,
Organism=Escherichia coli, GI1790488, Length=394, Percent_Identity=35.7868020304569, Blast_Score=265, Evalue=5e-72,
Organism=Caenorhabditis elegans, GI71981858, Length=388, Percent_Identity=34.5360824742268, Blast_Score=233, Evalue=2e-61,
Organism=Caenorhabditis elegans, GI25147133, Length=384, Percent_Identity=35.4166666666667, Blast_Score=233, Evalue=2e-61,
Organism=Caenorhabditis elegans, GI17569539, Length=393, Percent_Identity=30.2798982188295, Blast_Score=202, Evalue=2e-52,
Organism=Caenorhabditis elegans, GI25147136, Length=203, Percent_Identity=38.423645320197, Blast_Score=141, Evalue=8e-34,
Organism=Caenorhabditis elegans, GI17569537, Length=393, Percent_Identity=26.4631043256997, Blast_Score=129, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI17550384, Length=260, Percent_Identity=30.3846153846154, Blast_Score=125, Evalue=3e-29,
Organism=Saccharomyces cerevisiae, GI6323055, Length=398, Percent_Identity=32.9145728643216, Blast_Score=214, Evalue=2e-56,
Organism=Saccharomyces cerevisiae, GI6322743, Length=422, Percent_Identity=31.042654028436, Blast_Score=188, Evalue=1e-48,
Organism=Drosophila melanogaster, GI24580972, Length=388, Percent_Identity=36.0824742268041, Blast_Score=244, Evalue=8e-65,
Organism=Drosophila melanogaster, GI24580970, Length=388, Percent_Identity=36.0824742268041, Blast_Score=244, Evalue=1e-64,
Organism=Drosophila melanogaster, GI19920542, Length=378, Percent_Identity=36.7724867724868, Blast_Score=243, Evalue=2e-64,
Organism=Drosophila melanogaster, GI24654046, Length=400, Percent_Identity=32.5, Blast_Score=228, Evalue=5e-60,
Organism=Drosophila melanogaster, GI19922362, Length=400, Percent_Identity=32.5, Blast_Score=228, Evalue=7e-60,

Paralogues:

None

Copy number: 6,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000796
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 44581; Mature: 44450

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLFEQLPSFSPDSILGLAQAFQEDPREDKINLLLGTYEREKSRYGGFSSVRKAQTVFFG
CCHHHHCCCCCCHHHHHHHHHHHCCCCCCCEEEEEECHHHHHHHCCCHHHHHHHHEEEEC
DEKDKNYLPIRGSSVFLDQMAALCFGEIDANRWTGVQAVGGTGALHLGALVYAKSSLAGK
CCCCCCEECCCCCHHHHHHHHHHHHHCCCCCCCCCEEECCCCCHHHHHHHHHHHHCCCCE
VYIPAQTWGNHSRIFSRLGLSLEHYPYYDQEKKDLDLQGLKASLRDAPEASLILLHCCCH
EEEECCCCCCHHHHHHHHCCCEECCCCCCCCCCCCCHHHHHHHHCCCCCHHEEEEEEECC
NPTGKDIPLSEWPEIIAIIKDRGLIPFFDMAYLGFANGIVEDRRPVRLCIEAGVATFVAG
CCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCHHCCCCHHHHHHHHHHHHHHHC
SCSKNFSLYGSRVGFFGVVHQDKTDLSRILSFLEEQIRGEYSSPAREGVAIVTSILENPY
CCCCCCEEECCCEEEEEEEECCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCC
LRQEWGLELNGIRQSLEEIRANFVIAMREVAGHSFDFIASQKGFFGYPGFSKEQVVFLRE
CHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHCCCCCCCCCCCCCCCCEEEEEH
ELGIYTTAGGRFNLNGITDKNINRVIHGFAKAYEYSRSVS
HCCEEEECCCEEEECCCCCCHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SLFEQLPSFSPDSILGLAQAFQEDPREDKINLLLGTYEREKSRYGGFSSVRKAQTVFFG
CHHHHCCCCCCHHHHHHHHHHHCCCCCCCEEEEEECHHHHHHHCCCHHHHHHHHEEEEC
DEKDKNYLPIRGSSVFLDQMAALCFGEIDANRWTGVQAVGGTGALHLGALVYAKSSLAGK
CCCCCCEECCCCCHHHHHHHHHHHHHCCCCCCCCCEEECCCCCHHHHHHHHHHHHCCCCE
VYIPAQTWGNHSRIFSRLGLSLEHYPYYDQEKKDLDLQGLKASLRDAPEASLILLHCCCH
EEEECCCCCCHHHHHHHHCCCEECCCCCCCCCCCCCHHHHHHHHCCCCCHHEEEEEEECC
NPTGKDIPLSEWPEIIAIIKDRGLIPFFDMAYLGFANGIVEDRRPVRLCIEAGVATFVAG
CCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCHHCCCCHHHHHHHHHHHHHHHC
SCSKNFSLYGSRVGFFGVVHQDKTDLSRILSFLEEQIRGEYSSPAREGVAIVTSILENPY
CCCCCCEEECCCEEEEEEEECCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCC
LRQEWGLELNGIRQSLEEIRANFVIAMREVAGHSFDFIASQKGFFGYPGFSKEQVVFLRE
CHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHCCCCCCCCCCCCCCCCEEEEEH
ELGIYTTAGGRFNLNGITDKNINRVIHGFAKAYEYSRSVS
HCCEEEECCCEEEECCCCCCHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]