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Identifier: 15834627

GI number: 15834627

Start: 1300

End: 2697

Strand: Reverse

Name: Not Available

Synonym: TC0002

Alternate gene names: 15834627

Gene position: 2697-1300 (Counterclockwise)

Preceding gene: 15834628

Following gene: NA

Centisome position: 0.25

GC content: 40.77

Gene sequence:

>1398_bases
ATGAAGATAATAGTTTCTCGTGGATTAGATCTGTCTTTAAAAGGAGCCCCTAAGGAATCGGGTTTTTGCGGAAAAGTGGA
TCCCGCTTTTGTTTCCGTGGATCTGAGACCTTTTGCTCCCCTACCACTTGGTGTGAAAGTTTCTCCAGGAGACCAGATTA
CAGCTGGTTCTCCCTTAGCGGAATATAAGTCTTTCCCAGGTGTTTTCATCACCTCGTCGGTTGATGGAGAGGTTATCGAA
ATCCGTAGAGGAAGTAAGCGGGCTCTTTTGGATATCGTGATTAAAAAAAAGCCTGGGGTTTCTCAAACGAAGTTCTCTTA
TGACCTCCACGCTTTATCTCAAAAGGAGCTTTTAGAAGTCTTTAAAAAAGAAGGGCTTTTTACCCTTTTTAAACAAAGAC
CTTTCAATATCCCAGCGCTCCCAACACAATCCCCTAGAGATGTTTTTATTAACTTAGCGGACAATCGTCCATTCACCCCA
TCTGTAGAAAAACATCTAAGTCTTTTCTCTTCAAAAGAAGATGGTTATTACATTTTTGTTGTGGGAGTTCAGGCTATAGC
AAAACTATTTGGTCTCAAACCACATATTGTTTCCACAGATAGGCTCTCTTTACCTACCCAAGATTTAATATCTGTAGCTC
ATTTACATACAATAGCTGGTCCTTACCCTTCGGGATCTCCTTCGACCCATATTCATCATATCGCACGAATTCGCAATGAC
AGGGATATCGTATTCACAATTAGCTTCCAAGAAGTCCTCTCTATCGGCCATCTATTCTTAAAGGGATTTTTCCTAGGACA
ACAAGTCGTTGCATTAGCAGGATCTGCTCTCCCGCCTTCTCAAAGGAAATATCTGATCACAGCAAAAGGAGCCAGCTTCA
AAGACTTGTTACCACAAGAAATCTTCTCTTCCAACGATGTCAGTTTAATTTCGGGGGATCCTCTTACAGGAAGATTGTGT
AACAAAGAAGAAAATCCTTGTTTAGGCATGCGGGACCATACCATAACGATTCTTCCAAACCCTAAAACCCGAGAGATGTT
TAGTTTCTTACGATTAGGATGGAATAAACTTACGGTCACCAGAACCTATCTCTCTGGATTCTTCAAGAGAAAACGCGTGT
TCATGGATATGAATACCAATTTACACGGGGAAAAACGCCCAATCATTGATTCTGAAATCTATGAGAAAGTTTCGGCAATT
GCAGTTCCTGTAGCCCCTCTTATTAAAGCTTTAGAAACTCAAAATTTTGAAGAAGCGTGTCGCTTGGGACTCTTAGAAGT
CTCCCCAGAAGATTTTGCTCTACCAACATTTATAGATCCTTCTAAAACAGAGATGTTTGCTATTGTAAAAGAAGCTCTCA
TCCGTTACGCGAAAGAAAATGTTTTGACACCTCTGTAA

Upstream 100 bases:

>100_bases
CTCAGGAAAATCTCCCACTCCCAAAGCAAAATCTAGCTCTCCGAAAAAAAGTAAGAAAAAAAATTGGATTCCCTTATAAA
AACTTCTATAATCCCGAGAC

Downstream 100 bases:

>100_bases
TTTTTTAGGTGGTTCTTCAAAGAACTTTTTCCTTAAAAAGGAAGAGCGTCTCTAGCTAGCCATTCTAAAACCCATGGAGT
TGCATAGCTAATTATAGCCG

Product: Na(+)-translocating NADH-quinone reductase subunit A

Products: NA

Alternate protein names: Na(+)-NQR subunit A; Na(+)-translocating NQR subunit A; NQR complex subunit A; NQR-1 subunit A

Number of amino acids: Translated: 465; Mature: 465

Protein sequence:

>465_residues
MKIIVSRGLDLSLKGAPKESGFCGKVDPAFVSVDLRPFAPLPLGVKVSPGDQITAGSPLAEYKSFPGVFITSSVDGEVIE
IRRGSKRALLDIVIKKKPGVSQTKFSYDLHALSQKELLEVFKKEGLFTLFKQRPFNIPALPTQSPRDVFINLADNRPFTP
SVEKHLSLFSSKEDGYYIFVVGVQAIAKLFGLKPHIVSTDRLSLPTQDLISVAHLHTIAGPYPSGSPSTHIHHIARIRND
RDIVFTISFQEVLSIGHLFLKGFFLGQQVVALAGSALPPSQRKYLITAKGASFKDLLPQEIFSSNDVSLISGDPLTGRLC
NKEENPCLGMRDHTITILPNPKTREMFSFLRLGWNKLTVTRTYLSGFFKRKRVFMDMNTNLHGEKRPIIDSEIYEKVSAI
AVPVAPLIKALETQNFEEACRLGLLEVSPEDFALPTFIDPSKTEMFAIVKEALIRYAKENVLTPL

Sequences:

>Translated_465_residues
MKIIVSRGLDLSLKGAPKESGFCGKVDPAFVSVDLRPFAPLPLGVKVSPGDQITAGSPLAEYKSFPGVFITSSVDGEVIE
IRRGSKRALLDIVIKKKPGVSQTKFSYDLHALSQKELLEVFKKEGLFTLFKQRPFNIPALPTQSPRDVFINLADNRPFTP
SVEKHLSLFSSKEDGYYIFVVGVQAIAKLFGLKPHIVSTDRLSLPTQDLISVAHLHTIAGPYPSGSPSTHIHHIARIRND
RDIVFTISFQEVLSIGHLFLKGFFLGQQVVALAGSALPPSQRKYLITAKGASFKDLLPQEIFSSNDVSLISGDPLTGRLC
NKEENPCLGMRDHTITILPNPKTREMFSFLRLGWNKLTVTRTYLSGFFKRKRVFMDMNTNLHGEKRPIIDSEIYEKVSAI
AVPVAPLIKALETQNFEEACRLGLLEVSPEDFALPTFIDPSKTEMFAIVKEALIRYAKENVLTPL
>Mature_465_residues
MKIIVSRGLDLSLKGAPKESGFCGKVDPAFVSVDLRPFAPLPLGVKVSPGDQITAGSPLAEYKSFPGVFITSSVDGEVIE
IRRGSKRALLDIVIKKKPGVSQTKFSYDLHALSQKELLEVFKKEGLFTLFKQRPFNIPALPTQSPRDVFINLADNRPFTP
SVEKHLSLFSSKEDGYYIFVVGVQAIAKLFGLKPHIVSTDRLSLPTQDLISVAHLHTIAGPYPSGSPSTHIHHIARIRND
RDIVFTISFQEVLSIGHLFLKGFFLGQQVVALAGSALPPSQRKYLITAKGASFKDLLPQEIFSSNDVSLISGDPLTGRLC
NKEENPCLGMRDHTITILPNPKTREMFSFLRLGWNKLTVTRTYLSGFFKRKRVFMDMNTNLHGEKRPIIDSEIYEKVSAI
AVPVAPLIKALETQNFEEACRLGLLEVSPEDFALPTFIDPSKTEMFAIVKEALIRYAKENVLTPL

Specific function: NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to nqrE are probably involved in the second step, the conversion of ubisemiqui

COG id: COG1726

COG function: function code C; Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nqrA family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NQRA_CHLMU (Q9PLU3)

Other databases:

- EMBL:   AE002160
- PIR:   C81751
- RefSeq:   NP_296386.1
- GeneID:   1245525
- GenomeReviews:   AE002160_GR
- KEGG:   cmu:TC0002
- TIGR:   TC_0002
- HOGENOM:   HBG413878
- OMA:   EYGPILR
- ProtClustDB:   PRK05352
- BioCyc:   CMUR243161:TC_0002-MONOMER
- HAMAP:   MF_00425
- InterPro:   IPR008703
- InterPro:   IPR022615
- TIGRFAMs:   TIGR01936

Pfam domain/function: PF05896 NQRA; PF11973 NQRA_SLBB

EC number: NA

Molecular weight: Translated: 51590; Mature: 51590

Theoretical pI: Translated: 9.72; Mature: 9.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIIVSRGLDLSLKGAPKESGFCGKVDPAFVSVDLRPFAPLPLGVKVSPGDQITAGSPLA
CEEEEECCCEEEECCCCCCCCCCCCCCCEEEEEECCCCCCCCCCEEECCCCCCCCCCCHH
EYKSFPGVFITSSVDGEVIEIRRGSKRALLDIVIKKKPGVSQTKFSYDLHALSQKELLEV
HHHCCCCEEEEECCCCCEEEEECCCCCEEEEEEEECCCCCCCCEEEHHHHHCCHHHHHHH
FKKEGLFTLFKQRPFNIPALPTQSPRDVFINLADNRPFTPSVEKHLSLFSSKEDGYYIFV
HHHCCCEEEHHCCCCCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHCCCCCCEEEEE
VGVQAIAKLFGLKPHIVSTDRLSLPTQDLISVAHLHTIAGPYPSGSPSTHIHHIARIRND
EEHHHHHHHHCCCCCEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCC
RDIVFTISFQEVLSIGHLFLKGFFLGQQVVALAGSALPPSQRKYLITAKGASFKDLLPQE
CEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCHHHHCHHH
IFSSNDVSLISGDPLTGRLCNKEENPCLGMRDHTITILPNPKTREMFSFLRLGWNKLTVT
HHCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHCCCCCEEEE
RTYLSGFFKRKRVFMDMNTNLHGEKRPIIDSEIYEKVSAIAVPVAPLIKALETQNFEEAC
HHHHHHHHHHCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHCCCHHHHH
RLGLLEVSPEDFALPTFIDPSKTEMFAIVKEALIRYAKENVLTPL
CCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKIIVSRGLDLSLKGAPKESGFCGKVDPAFVSVDLRPFAPLPLGVKVSPGDQITAGSPLA
CEEEEECCCEEEECCCCCCCCCCCCCCCEEEEEECCCCCCCCCCEEECCCCCCCCCCCHH
EYKSFPGVFITSSVDGEVIEIRRGSKRALLDIVIKKKPGVSQTKFSYDLHALSQKELLEV
HHHCCCCEEEEECCCCCEEEEECCCCCEEEEEEEECCCCCCCCEEEHHHHHCCHHHHHHH
FKKEGLFTLFKQRPFNIPALPTQSPRDVFINLADNRPFTPSVEKHLSLFSSKEDGYYIFV
HHHCCCEEEHHCCCCCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHHHCCCCCCEEEEE
VGVQAIAKLFGLKPHIVSTDRLSLPTQDLISVAHLHTIAGPYPSGSPSTHIHHIARIRND
EEHHHHHHHHCCCCCEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCC
RDIVFTISFQEVLSIGHLFLKGFFLGQQVVALAGSALPPSQRKYLITAKGASFKDLLPQE
CEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCHHHHCHHH
IFSSNDVSLISGDPLTGRLCNKEENPCLGMRDHTITILPNPKTREMFSFLRLGWNKLTVT
HHCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHCCCCCEEEE
RTYLSGFFKRKRVFMDMNTNLHGEKRPIIDSEIYEKVSAIAVPVAPLIKALETQNFEEAC
HHHHHHHHHHCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHCCCHHHHH
RLGLLEVSPEDFALPTFIDPSKTEMFAIVKEALIRYAKENVLTPL
CCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10684935